Education
Ph.D. in Imperial College of London, UK, 2012
Current Position
Assistant Head, Biomedical Sciences Industry Partnership Office, A*STAR, Singapore
Publications
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Leow, S. C., Poschmann, J., Too, P. G., Yin, J., Joseph, R., McFarlane, C., Dogra, S., Shabbir, A., Ingham, P. W., Prabhakar, S., Leow, M. K., Lee, Y. S., Ng, K. L., Chong, Y. S., Gluckman, P. D. and Stunkel, W. (2016). The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis. Development 143(6): 950-961.
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Koh, C. M., Khattar, E., Leow, S. C., Liu, C. Y., Muller, J., Ang, W. X., Li, Y., Franzoso, G., Li, S., Guccione, E. and Tergaonkar, V. (2015). Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity. J Clin Invest 125(5): 2109-2122.
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Li, L., Ng, D. S., Mah, W. C., Almeida, F. F., Rahmat, S. A., Rao, V. K., Leow, S. C., Laudisi, F., Peh, M. T., Goh, A. M., Lim, J. S., Wright, G. D., Mortellaro, A., Taneja, R., Ginhoux, F., Lee, C. G., Moore, P. K. and Lane, D. P. (2015). A unique role for p53 in the regulation of M2 macrophage polarization. Cell Death Differ 22(7): 1081-1093.
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Sukarieh, R., Joseph, R., Leow, S. C., Li, Y., Loffler, M., Aris, I. M., Tan, J. H., Teh, A. L., Chen, L., Holbrook, J. D., Ng, K. L., Lee, Y. S., Chong, Y. S., Summers, S. A., Gluckman, P. D. and Stunkel, W. (2014). Molecular pathways reflecting poor intrauterine growth are found in Wharton's jelly-derived mesenchymal stem cells. Hum Reprod 29(10): 2287-2301.
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Ghosh, A., Saginc, G., Leow, S. C., Khattar, E., Shin, E. M., Yan, T. D., Wong, M., Zhang, Z., Li, G., Sung, W. K., Zhou, J., Chng, W. J., Li, S., Liu, E. and Tergaonkar, V. (2012). Telomerase directly regulates NF-kappaB-dependent transcription. Nat Cell Biol 14(12): 1270-1281.
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Mauro, C., Leow, S. C., Anso, E., Rocha, S., Thotakura, A. K., Tornatore, L., Moretti, M., De Smaele, E., Beg, A. A., Tergaonkar, V., Chandel, N. S. and Franzoso, G. (2011). NF-kappaB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration. Nat Cell Biol 13(10): 1272-1279.
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Bist, P., Leow, S. C., Phua, Q. H., Shu, S., Zhuang, Q., Loh, W. T., Nguyen, T. H., Zhou, J. B., Hooi, S. C. and Lim, L. H. (2011). Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-kappaB: implication in breast cancer metastasis. Oncogene 30(28): 3174-3185.
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Fullwood, M. J., Liu, M. H., Pan, Y. F., Liu, J., Xu, H., Mohamed, Y. B., Orlov, Y. L., Velkov, S., Ho, A., Mei, P. H., Chew, E. G., Huang, P. Y., Welboren, W. J., Han, Y., Ooi, H. S., Ariyaratne, P. N., Vega, V. B., Luo, Y., Tan, P. Y., Choy, P. Y., Wansa, K. D., Zhao, B., Lim, K. S., Leow, S. C., Yow, J. S., Joseph, R., Li, H., Desai, K. V., Thomsen, J. S., Lee, Y. K., Karuturi, R. K., Herve, T., Bourque, G., Stunnenberg, H. G., Ruan, X., Cacheux-Rataboul, V., Sung, W. K., Liu, E. T., Wei, C. L., Cheung, E. and Ruan, Y. (2009). An oestrogen-receptor-alpha-bound human chromatin interactome. Nature 462(7269): 58-64.