How glycoproteomics helps in understanding of disease and finding associated marker?

Thanks for the question. We will see in the webinar that glycoproteomics methods can shed light on the glycosylation status not only of "healthy" cells, but also in presence of disease. For example, glycoproteomics has helped understanding if alterations to the glycosylation landscape are at the basis of an observed human disease, guiding the selection of possible candidate proteins to further investigate, while proposing a molecular mechanism for pathogenesis. These topics will be covered during the webinar, where I will bring the example of how protein O-mannosylation is a crucial modification in human health and disease.