Education
Ph.D in Physiology, Sun Yat-sen University, China, 2006
Current position
Assistant Professor, Biological Sciences, University of Toledo, United States
Publications
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Du, J., Price, M. P., Taugher, R. J., Grigsby, D., Ash, J. J., Stark, A. C., Hossain Saad, M. Z., Singh, K., Mandal, J., Wemmie, J. A. and Welsh, M. J. (2017). Transient acidosis while retrieving a fear-related memory enhances its lability. Elife 6.
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Du, J., Zubayer, H. S. and Mandal, J. (2017). Protons: A neurotransmitter in the brain. Edorium J Cell Biol (3): 1-3.
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Yue, Z., Xie, J., Yu, A. S., Stock, J., Du, J. and Yue, L. (2015). Role of TRP channels in the cardiovascular system. Am J Physiol Heart Circ Physiol 308(3): H157-182.
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Du, J., Reznikov, L. R. and Welsh, M. J. (2014). Expression and activity of acid-sensing ion channels in the mouse anterior pituitary. PLoS One 9(12): e115310.
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Du, J., Reznikov, L. R., Price, M. P., Zha, X. M., Lu, Y., Moninger, T. O., Wemmie, J. A. and Welsh, M. J. (2014). Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala. Proc Natl Acad Sci U S A 111(24): 8961-8966.
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Kreple, C. J., Lu, Y., Taugher, R. J., Schwager-Gutman, A. L., Du, J., Stump, M., Wang, Y., Ghobbeh, A., Fan, R., Cosme, C. V., Sowers, L. P., Welsh, M. J., Radley, J. J., LaLumiere, R. T. and Wemmie, J. A. (2014). Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity. Nat Neurosci 17(8): 1083-1091.
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Reznikov, L. R., Dong, Q., Chen, J. H., Moninger, T. O., Park, J. M., Zhang, Y., Du, J., Hildebrand, M. S., Smith, R. J., Randak, C. O., Stoltz, D. A. and Welsh, M. J. (2013). CFTR-deficient pigs display peripheral nervous system defects at birth. Proc Natl Acad Sci U S A 110(8): 3083-3088.
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Vralsted, V. C., Price, M. P., Du, J., Schnizler, M., Wunsch, A. M., Ziemann, A. E., Welsh, M. J. and Wemmie, J. A. (2011). Expressing acid-sensing ion channel 3 in the brain alters acid-evoked currents and impairs fear conditioning. Genes Brain Behav 10(4): 444-450.
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Zuo, W. L., Du, J. Y., Huang, J. H., Li, S., Zhang, G., Chen, S. L., Ruan, Y. C., Cheng, C. H. and Zhou, W. L. (2011). Tyrosine phosphorylation modulates store-operated calcium entry in cultured rat epididymal basal cells. J Cell Physiol 226(4): 1069-1073.
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Xie, J., Sun, B., Du, J., Yang, W., Chen, H. C., Overton, J. D., Runnels, L. W. and Yue, L. (2011). Phosphatidylinositol 4,5-bisphosphate (PIP(2)) controls magnesium gatekeeper TRPM6 activity. Sci Rep 1: 146.
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Du, J., Xie, J., Zhang, Z., Tsujikawa, H., Fusco, D., Silverman, D., Liang, B. and Yue, L. (2010). TRPM7-mediated Ca2+ signals confer fibrogenesis in human atrial fibrillation. Circ Res 106(5): 992-1003.
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Du, J., Xie, J. and Yue, L. (2009). Intracellular calcium activates TRPM2 and its alternative spliced isoforms. Proc Natl Acad Sci U S A 106(17): 7239-7244.
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Du, J., Xie, J. and Yue, L. (2009). Modulation of TRPM2 by acidic pH and the underlying mechanisms for pH sensitivity. J Gen Physiol 134(6): 471-488.
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Heeringa, S. F., Moller, C. C., Du, J., Yue, L., Hinkes, B., Chernin, G., Vlangos, C. N., Hoyer, P. F., Reiser, J. and Hildebrandt, F. (2009). A novel TRPC6 mutation that causes childhood FSGS. PLoS One 4(11): e7771.
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Xiang, H., Wang, L., Cui, J., Du, J., Wang, K. and Xu, A. (2009). Effects of recombinant neurotoxins on single Na(+) channels in isolated rat hippocampal neurons. J Biochem Mol Toxicol 23(4): 244-255.
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Du, J. Y., Zuo, W. L., Ruan, Y. C., Yang, Z. H., Chen, M. H., Chen, S. L., Li, S., Wu, Z. L., Xiang, H. and Zhou, W. L. (2009). Stimulating effects of dopamine on chloride transport across the rat caudal epididymal epithelium in culture. Biol Reprod 80(1): 13-23.
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Ruan, Y. C., Wang, Z., Du, J. Y., Zuo, W. L., Guo, J. H., Zhang, J., Wu, Z. L., Wong, H. Y., Chung, Y. W., Chan, H. C. and Zhou, W. L. (2008). Regulation of smooth muscle contractility by the epithelium in rat vas deferens: role of ATP-induced release of PGE2. J Physiol 586(20): 4843-4857.
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Chen, M., Du, J., Jiang, W., Zuo, W., Wang, F., Li, M., Chan, H. and Zhou, W. (2008). Functional expression of cystic fibrosis transmembrane conductance regulator in rat oviduct epithelium. Acta Biochim Biophys Sin (Shanghai) 40(10): 864-872.
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Yang, Z. H., Yu, H. J., Pan, A., Du, J. Y., Ruan, Y. C., Ko, W. H., Chan, H. C. and Zhou, W. L. (2008). Cellular mechanisms underlying the laxative effect of flavonol naringenin on rat constipation model. PLoS One 3(10): e3348.
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Zhou, W. L., Zuo, W. L., Ruan, Y. C., Wang, Z., Du, J. Y., Xiong, Y. and Chan, H. C. (2007). The role of extracellular ATP in the male reproductive tract. Sheng Li Xue Bao 59(4): 487-494.
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Zhang, L., Tang, S. B., Xiang, H., Du, J. Y., Huang, B., Luo, Y. and Chen, X. G. (2007). Effect of supernatant fluid of retinal cells on dynamics of sodium ion channels of neuron-like cells derived from embryonic stem cells. Chin J Ocul Fundus Dis 23: 91-93.
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Li, M., Du, J., Jiang, J., Ratzan, W., Su, L. T., Runnels, L. W. and Yue, L. (2007). Molecular determinants of Mg2+ and Ca2+ permeability and pH sensitivity in TRPM6 and TRPM7. J Biol Chem 282(35): 25817-25830.
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Zhong, X. F., Li, Y. P., Ge, J., Huang, B., Peng, F. H., Du, J. Y., Lin, J. X., Wu, Z. L. and Liu, J. B. (2006). Isolation and culture of tumor stem cells in human retinoblastomas. Chinese Journal of pathophysiology 22(6): 1177-1181.
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Du, J. Y., Ruan, Y. C., Zuo, W. L., Yang, Z. H., Chen, M. H., Wu, Z. L., Xiang, H. and Zhou, W. L. (2006). Cellular mechanisms of carbachol-stimulated Cl- secretion in rat epididymal epithelium. Biol Reprod 75(3): 407-413.
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Du, J. Y., Zuo, W. L., Chen, M. H., Xiang, H. and Zhou, W. L. (2006). Involvement of muscarinic acetylcholine receptors in chloride secretion by cultured rat epididymal epithelium. Cell Biol Int 30(9): 741-746.
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Ou, J., Wang, L., Ding, X., Du, J., Zhang, Y., Chen, H. and Xu, A. (2004). Stationary phase protein overproduction is a fundamental capability of Escherichia coli. Biochem Biophys Res Commun 314(1): 174-180.
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Wang, L., Ou, J., Peng, L., Zhong, X., Du, J., Liu, Y., Huang, Y., Liu, W., Zhang, Y., Dong, M. and Xu, A. L. (2004). Functional expression and characterization of four novel neurotoxins from sea anemone Anthopleura sp. Biochem Biophys Res Commun 313(1): 163-170.