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Carlos Cordon-Cardo

Education

Ph.D. in Cell Biology and Genetics, Cornell University Medical College, Graduate School of Medical Sciences, New York, 1985

Current position

Adjunct Professor, Departments of Pathology and Urology, CUMC (2011-present)
Irene Heinz Given & John LaPorte Given Professor and Chairman, Department of Pathology; Mount Sinai Health System. Professor, Department of Genetics and Genomic Sciences; Professor, Department of Oncological Sciences – Icahn School of Medicine at Mount Sinai. Professor and Director, Department of Pathology, Mount Sinai Hospital (2011-present)

Publications

  1. Sia, D., Losic, B., Moeini, A., Cabellos, L., Hao, K., Revill, K., Bonal, D., Miltiadous, O., Zhang, Z., Hoshida, Y., Cornella, H., Castillo-Martin, M., Pinyol, R., Kasai, Y., Roayaie, S., Thung, S. N., Fuster, J., Schwartz, M. E., Waxman, S., Cordon-Cardo, C., Schadt, E., Mazzaferro, V. and Llovet, J. M. (2015). Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma. Nat Commun 6: 6087.
  2. Di Sante, G., Pestell, T. G., Casimiro, M. C., Bisetto, S., Powell, M. J., Lisanti, M. P., Cordon-Cardo, C., Castillo-Martin, M., Bonal, D. M., Debattisti, V., Chen, K., Wang, L., He, X., McBurney, M. W. and Pestell, R. G. (2015). Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria. Am J Pathol 185(1): 266-279.
  3. Vidal, S. J., Rodriguez-Bravo, V., Quinn, S. A., Rodriguez-Barrueco, R., Lujambio, A., Williams, E., Sun, X., de la Iglesia-Vicente, J., Lee, A., Readhead, B., Chen, X., Galsky, M., Esteve, B., Petrylak, D. P., Dudley, J. T., Rabadan, R., Silva, J. M., Hoshida, Y., Lowe, S. W., Cordon-Cardo, C. and Domingo-Domenech, J. (2015). A targetable GATA2-IGF2 axis confers aggressiveness in lethal prostate cancer. Cancer Cell 27(2): 223-239.
  4. Danielson, L. S., Reavie, L., Coussens, M., Davalos, V., Castillo-Martin, M., Guijarro, M. V., Coffre, M., Cordon-Cardo, C., Aifantis, I., Ibrahim, S., Liu, C., Koralov, S. B. and Hernando, E. (2015). Limited miR-17-92 overexpression drives hematologic malignancies. Leuk Res 39(3): 335-341.
  5. Guarnerio, J., Riccardi, L., Taulli, R., Maeda, T., Wang, G., Hobbs, R. M., Song, M. S., Sportoletti, P., Bernardi, R., Bronson, R. T., Castillo-Martin, M., Cordon-Cardo, C., Lunardi, A. and Pandolfi, P. P. (2015). A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells. Cancer Discov 5(4): 396-409.
  6. Gaya, J. M., Lopez-Martinez, J. M., Karni-Schmidt, O., Bonal, D. M., Algaba, F., Palou, J., Villavicencio, H., Benson, M. C., Cordon-Cardo, C. and Castillo-Martin, M. (2015). △Np63 expression is a protective factor of progression in clinical high grade T1 bladder cancer. J Urol 193(4): 1144-1150.
  7. Lunardi, A., Varmeh, S., Chen, M., Taulli, R., Guarnerio, J., Ala, U., Seitzer, N., Ishikawa, T., Carver, B. S., Hobbs, R. M., Quarantotti, V., Ng, C., Berger, A. H., Nardella, C., Poliseno, L., Montironi, R., Castillo-Martin, M., Cordon-Cardo, C., Signoretti, S. and Pandolfi, P. P. (2015). Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis. Cancer Discov 5(5): 550-563.
  8. Ugalde-Olano, A., Egia, A., Fernandez-Ruiz, S., Loizaga-Iriarte, A., Zuniga-Garcia, P., Garcia, S., Royo, F., Lacasa-Viscasillas, I., Castro, E., Cortazar, A. R., Zabala-Letona, A., Martin-Martin, N., Arruabarrena-Aristorena, A., Torrano-Moya, V., Valcarcel-Jimenez, L., Sanchez-Mosquera, P., Caro-Maldonado, A., Gonzalez-Tampan, J., Cachi-Fuentes, G., Bilbao, E., Montero, R., Fernandez, S., Arrieta, E., Zorroza, K., Castillo-Martin, M., Serra, V., Salazar, E., Macias-Camara, N., Tabernero, J., Baselga, J., Cordon-Cardo, C., Aransay, A. M., Villar, A. D., Iovanna, J. L., Falcon-Perez, J. M., Unda, M., Bilbao, R. and Carracedo, A. (2015). Methodological aspects of the molecular and histological study of prostate cancer: focus on PTEN. Methods 77-78: 25-30.
  9. Nowak, D. G., Cho, H., Herzka, T., Watrud, K., DeMarco, D. V., Wang, V. M., Senturk, S., Fellmann, C., Ding, D., Beinortas, T., Kleinman, D., Chen, M., Sordella, R., Wilkinson, J. E., Castillo-Martin, M., Cordon-Cardo, C., Robinson, B. D. and Trotman, L. C. (2015). MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discov 5(6): 636-651.
  10. Shantha Kumara, H., Kirchoff, D., Caballero, O. L., Su, T., Ahmed, A., Herath, S. A., Njoh, L., Cekic, V., Simpson, A. J., Cordon-Cardo, C. and Whelan, R. L. (2015). Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target. Oncoscience 2(6): 607-614.
  11. Rodriguez-Barrueco, R., Yu, J., Saucedo-Cuevas, L. P., Olivan, M., Llobet-Navas, D., Putcha, P., Castro, V., Murga-Penas, E. M., Collazo-Lorduy, A., Castillo-Martin, M., Alvarez, M., Cordon-Cardo, C., Kalinsky, K., Maurer, M., Califano, A. and Silva, J. M. (2015). Inhibition of the autocrine IL-6-JAK2-STAT3-calprotectin axis as targeted therapy for HR-/HER2+ breast cancers. Genes Dev 29(15): 1631-1648.
  12. Epping, M. T., Lunardi, A., Nachmani, D., Castillo-Martin, M., Thin, T. H., Cordon-Cardo, C. and Pandolfi, P. P. (2015). TSPYL2 is an essential component of the REST/NRSF transcriptional complex for TGFβ signaling activation. Cell Death Differ 22(8): 1353-1362.
  13. Herranz, D., Ambesi-Impiombato, A., Sudderth, J., Sanchez-Martin, M., Belver, L., Tosello, V., Xu, L., Wendorff, A. A., Castillo, M., Haydu, J. E., Marquez, J., Mates, J. M., Kung, A. L., Rayport, S., Cordon-Cardo, C., DeBerardinis, R. J. and Ferrando, A. A. (2015). Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia. Nat Med 21(10): 1182-1189.
  14. Williams, E. S., Rodriquez-Bravo, V., Chippada-Venkata, U., De Ia Iglesia-Vicente, J., Gong, Y., Galsky, M., Oh, W., Cordon-Cardo, C. and Domingo-Domenech, J. (2015). Generation of Prostate Cancer Patient Derived Xenograft Models from Circulating Tumor Cells. J Vis Exp(105): 53182.
  15. Castillo-Martin, M., Collazo Lorduy, A., Gladoun, N., Hyun, G. and Cordon-Cardo, C. (2015). H-RAS mutation is a key molecular feature of pediatric urothelial bladder cancer. A detailed report of three cases. J Pediatr Urol. (Epub ahead of print)
  16. Puzio-Kuter, A. M., Laddha, S. V., Castillo-Martin, M., Sun, Y., Cordon-Cardo, C., Chan, C. S. and Levine, A. J. (2015). Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma. Cell Death Differ 22(11): 1785-1791.
  17. Barber, A. G., Castillo-Martin, M., Bonal, D. M., Jia, A. J., Rybicki, B. A., Christiano, A. M. and Cordon-Cardo, C. (2015). PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer. Cancer Med 4(8): 1258-1271.
  18. Cho, H., Herzka, T., Zheng, W., Qi, J., Wilkinson, J. E., Bradner, J. E., Robinson, B. D., Castillo-Martin, M., Cordon-Cardo, C. and Trotman, L. C. (2014). RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis. Cancer Discov 4(3): 318-333.
  19. Vidal, S. J., Quinn, S. A., de la Iglesia-Vicente, J., Bonal, D. M., Rodriguez-Bravo, V., Firpo-Betancourt, A., Cordon-Cardo, C. and Domingo-Domenech, J. (2014). Isolation of cancer stem cells from human prostate cancer samples. J Vis Exp(85).
  20. Llobet-Navas, D., Rodriguez-Barrueco, R., Castro, V., Ugalde, A. P., Sumazin, P., Jacob-Sendler, D., Demircan, B., Castillo-Martin, M., Putcha, P., Marshall, N., Villagrasa, P., Chan, J., Sanchez-Garcia, F., Pe'er, D., Rabadan, R., Iavarone, A., Cordon-Cardo, C., Califano, A., Lopez-Otin, C., Ezhkova, E. and Silva, J. M. (2014). The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland. Genes Dev 28(7): 765-782.
  21. Ye, F., Wang, L., Castillo-Martin, M., McBride, R., Galsky, M. D., Zhu, J., Boffetta, P., Zhang, D. Y. and Cordon-Cardo, C. (2014). Biomarkers for bladder cancer management: present and future. Am J Clin Exp Urol 2(1): 1-14.
  22. Donovan, M. J. and Cordon-Cardo, C. (2014). Genomic analysis in active surveillance: predicting high-risk disease using tissue biomarkers. Curr Opin Urol 24(3): 303-310.
  23. Aydin, I. T., Melamed, R. D., Adams, S. J., Castillo-Martin, M., Demir, A., Bryk, D., Brunner, G., Cordon-Cardo, C., Osman, I., Rabadan, R. and Celebi, J. T. (2014). FBXW7 mutations in melanoma and a new therapeutic paradigm. J Natl Cancer Inst 106(6): dju107.
  24. Barber, A. G., Castillo-Martin, M., Bonal, D. M., Rybicki, B. A., Christiano, A. M. and Cordon-Cardo, C. (2014). Characterization of desmoglein expression in the normal prostatic gland. Desmoglein 2 is an independent prognostic factor for aggressive prostate cancer. PLoS One 9(6): e98786.
  25. Jia, A. Y., Castillo-Martin, M., Bonal, D. M., Sanchez-Carbayo, M., Silva, J. M. and Cordon-Cardo, C. (2014). MicroRNA-126 inhibits invasion in bladder cancer via regulation of ADAM9. Br J Cancer 110(12): 2945-2954.
  26. Harcharik, S., Bernardo, S., Moskalenko, M., Pan, M., Sivendran, M., Bell, H., Hall, L. D., Castillo-Martin, M., Fox, K., Cordon-Cardo, C., Chang, R., Sivendran, S., Phelps, R. G. and Saenger, Y. (2014). Defining the role of CD2 in disease progression and overall survival among patients with completely resected stage-II to -III cutaneous melanoma. J Am Acad Dermatol 70(6): 1036-1044.
  27. Vidal, S. J., Rodriguez-Bravo, V., Galsky, M., Cordon-Cardo, C. and Domingo-Domenech, J. (2014). Targeting cancer stem cells to suppress acquired chemotherapy resistance. Oncogene 33(36): 4451-4463.
  28. Herranz, D., Ambesi-Impiombato, A., Palomero, T., Schnell, S. A., Belver, L., Wendorff, A. A., Xu, L., Castillo-Martin, M., Llobet-Navas, D., Cordon-Cardo, C., Clappier, E., Soulier, J. and Ferrando, A. A. (2014). A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia. Nat Med 20(10): 1130-1137.
  29. Van Batavia, J., Yamany, T., Molotkov, A., Dan, H., Mansukhani, M., Batourina, E., Schneider, K., Oyon, D., Dunlop, M., Wu, X. R., Cordon-Cardo, C. and Mendelsohn, C. (2014). Bladder cancers arise from distinct urothelial sub-populations. Nat Cell Biol 16(10): 982-991, 981-985.
  30. Donovan, M. J. and Cordon-Cardo, C. (2014). Overcoming tumor heterogeneity in the molecular diagnosis of urological cancers. Expert Rev Mol Diagn 14(8): 1023-1031.
  31. Llobet-Navas, D., Rodriguez-Barrueco, R., de la Iglesia-Vicente, J., Olivan, M., Castro, V., Saucedo-Cuevas, L., Marshall, N., Putcha, P., Castillo-Martin, M., Bardot, E., Ezhkova, E., Iavarone, A., Cordon-Cardo, C. and Silva, J. M. (2014). The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor β in mammary epithelial cells. Mol Cell Biol 34(23): 4216-4231.
  32. Jia, A. Y., Castillo-Martin, M., Domingo-Domenech, J., Bonal, D. M., Sanchez-Carbayo, M., Silva, J. M. and Cordon-Cardo, C. (2013). A common MicroRNA signature consisting of miR-133a, miR-139-3p, and miR-142-3p clusters bladder carcinoma in situ with normal umbrella cells. Am J Pathol 182(4): 1171-1179.
  33. Donovan, M. J. and Cordon-Cardo, C. (2013). Predicting high-risk disease using tissue biomarkers. Curr Opin Urol 23(3): 245-251.
  34. Haupt, S., Mitchell, C., Corneille, V., Shortt, J., Fox, S., Pandolfi, P. P., Castillo-Martin, M., Bonal, D. M., Cordon-Cardo, C., Lozano, G. and Haupt, Y. (2013). Loss of PML cooperates with mutant p53 to drive more aggressive cancers in a gender-dependent manner. Cell Cycle 12(11): 1722-1731.
  35. Guijarro, M. V., Dahiya, S., Danielson, L. S., Segura, M. F., Vales-Lara, F. M., Menendez, S., Popiolek, D., Mittal, K., Wei, J. J., Zavadil, J., Cordon-Cardo, C., Pandolfi, P. P. and Hernando, E. (2013). Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling. Am J Pathol 182(6): 2015-2027.
  36. Wang, G., Lunardi, A., Zhang, J., Chen, Z., Ala, U., Webster, K. A., Tay, Y., Gonzalez-Billalabeitia, E., Egia, A., Shaffer, D. R., Carver, B., Liu, X. S., Taulli, R., Kuo, W. P., Nardella, C., Signoretti, S., Cordon-Cardo, C., Gerald, W. L. and Pandolfi, P. P. (2013). Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion. Nat Genet 45(7): 739-746.
  37. Lunardi, A., Ala, U., Epping, M. T., Salmena, L., Clohessy, J. G., Webster, K. A., Wang, G., Mazzucchelli, R., Bianconi, M., Stack, E. C., Lis, R., Patnaik, A., Cantley, L. C., Bubley, G., Cordon-Cardo, C., Gerald, W. L., Montironi, R., Signoretti, S., Loda, M., Nardella, C. and Pandolfi, P. P. (2013). A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer. Nat Genet 45(7): 747-755.
  38. Yang, Y., Wu, J., Demir, A., Castillo-Martin, M., Melamed, R. D., Zhang, G., Fukunaga-Kanabis, M., Perez-Lorenzo, R., Zheng, B., Silvers, D. N., Brunner, G., Wang, S., Rabadan, R., Cordon-Cardo, C. and Celebi, J. T. (2013). GAB2 induces tumor angiogenesis in NRAS-driven melanoma. Oncogene 32(31): 3627-3637.
  39. Piovan, E., Yu, J., Tosello, V., Herranz, D., Ambesi-Impiombato, A., Da Silva, A. C., Sanchez-Martin, M., Perez-Garcia, A., Rigo, I., Castillo, M., Indraccolo, S., Cross, J. R., de Stanchina, E., Paietta, E., Racevskis, J., Rowe, J. M., Tallman, M. S., Basso, G., Meijerink, J. P., Cordon-Cardo, C., Califano, A. and Ferrando, A. A. (2013). Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia. Cancer Cell 24(6): 766-776.
  40. Charytonowicz, E., Terry, M., Coakley, K., Telis, L., Remotti, F., Cordon-Cardo, C., Taub, R. N. and Matushansky, I. (2012). PPARγ agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma. J Clin Invest 122(3): 886-898.
  41. Donovan, M. J., Khan, F. M., Powell, D., Bayer-Zubek, V., Cordon-Cardo, C., Costa, J., Eastham, J. and Scardino, P. (2012). Postoperative systems models more accurately predict risk of significant disease progression than standard risk groups and a 10-year postoperative nomogram: potential impact on the receipt of adjuvant therapy after surgery. BJU Int 109(1): 40-45.
  42. Donovan, M. J., Khan, F. M., Bayer-Zubek, V., Powell, D., Costa, J. and Cordon-Cardo, C. (2012). A systems-based modelling approach using transurethral resection of the prostate (TURP) specimens yielded incremental prognostic significance to Gleason when predicting long-term outcome in men with localized prostate cancer. BJU Int 109(2): 207-213.
  43. Charytonowicz, E., Matushansky, I., Domenech, J. D., Castillo-Martin, M., Ladanyi, M., Cordon-Cardo, C. and Ziman, M. (2012). PAX7-FKHR fusion gene inhibits myogenic differentiation via NF-kappaB upregulation. Clin Transl Oncol 14(3): 197-206.
  44. Shen, T. H., Gladoun, N., Castillo-Martin, M., Bonal, D., Domingo-Domenech, J., Charytonowicz, D. and Cordon-Cardo, C. (2012). A BAC-based transgenic mouse specifically expresses an inducible Cre in the urothelium. PLoS One 7(4): e35243.
  45. Hoffman, A., Baxter, R., Nasar, A., Gardner, T. R., Kumara, S., Cordon-Cardo, C., Ahmed, A., Newman, R. A., Zmora, O. and Whelan, R. L. (2012). Perioperative polyphenon E, a green tea extract, does not affect the wound complication rate in mice after sham laparotomy yet has an inhibitory effect on wound healing. Surg Innov 19(4): 399-406.
  46. Puerta-Gil, P., Garcia-Baquero, R., Jia, A. Y., Ocana, S., Alvarez-Mugica, M., Alvarez-Ossorio, J. L., Cordon-Cardo, C., Cava, F. and Sanchez-Carbayo, M. (2012). miR-143, miR-222, and miR-452 are useful as tumor stratification and noninvasive diagnostic biomarkers for bladder cancer. Am J Pathol 180(5): 1808-1815.
  47. Subramaniam, P. S., Whye, D. W., Efimenko, E., Chen, J., Tosello, V., De Keersmaecker, K., Kashishian, A., Thompson, M. A., Castillo, M., Cordon-Cardo, C., Dave, U. P., Ferrando, A., Lannutti, B. J. and Diacovo, T. G. (2012). Targeting nonclassical oncogenes for therapy in T-ALL. Cancer Cell 21(4): 459-472.
  48. Samon, J. B., Castillo-Martin, M., Hadler, M., Ambesi-Impiobato, A., Paietta, E., Racevskis, J., Wiernik, P. H., Rowe, J. M., Jakubczak, J., Randolph, S., Cordon-Cardo, C. and Ferrando, A. A. (2012). Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia. Mol Cancer Ther 11(7): 1565-1575.
  49. Zhong, M., De Angelo, P., Osborne, L., Paniz-Mondolfi, A. E., Geller, M., Yang, Y., Linehan, W. M., Merino, M. J., Cordon-Cardo, C. and Cai, D. (2012). Translocation renal cell carcinomas in adults: a single-institution experience. Am J Surg Pathol 36(5): 654-662.
  50. Domingo-Domenech, J., Vidal, S. J., Rodriguez-Bravo, V., Castillo-Martin, M., Quinn, S. A., Rodriguez-Barrueco, R., Bonal, D. M., Charytonowicz, E., Gladoun, N., de la Iglesia-Vicente, J., Petrylak, D. P., Benson, M. C., Silva, J. M. and Cordon-Cardo, C. (2012). Suppression of acquired docetaxel resistance in prostate cancer through depletion of notch- and hedgehog-dependent tumor-initiating cells. Cancer Cell 22(3): 373-388.
  51. Papa, A., Cordon-Cardo, C., Bernardi, R. and Pandolfi, P. P. (2012). Compound In Vivo Inactivation of Pml and p53 Uncovers a Functional Interaction in Angiosarcoma Suppression. Genes Cancer 3(9-10): 599-603.
  52. Shantha Kumara, H. M., Grieco, M. J., Caballero, O. L., Su, T., Ahmed, A., Ritter, E., Gnjatic, S., Cekic, V., Old, L. J., Simpson, A. J., Cordon-Cardo, C. and Whelan, R. L. (2012). MAGE-A3 is highly expressed in a subset of colorectal cancer patients. Cancer Immun 12: 16.
  53. Karni-Schmidt, O., Castillo-Martin, M., Shen, T. H., Gladoun, N., Domingo-Domenech, J., Sanchez-Carbayo, M., Li, Y., Lowe, S., Prives, C. and Cordon-Cardo, C. (2011). Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression. Am J Pathol 178(3): 1350-1360.
  54. Powell, M. J., Casimiro, M. C., Cordon-Cardo, C., He, X., Yeow, W. S., Wang, C., McCue, P. A., McBurney, M. W. and Pestell, R. G. (2011). Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation. Cancer Res 71(3): 964-975.
  55. Smith, B. H., Gazda, L. S., Conn, B. L., Jain, K., Asina, S., Levine, D. M., Parker, T. S., Laramore, M. A., Martis, P. C., Vinerean, H. V., David, E. M., Qiu, S., Cordon-Cardo, C., Hall, R. D., Gordon, B. R., Diehl, C. H., Stenzel, K. H. and Rubin, A. L. (2011). Three-dimensional culture of mouse renal carcinoma cells in agarose macrobeads selects for a subpopulation of cells with cancer stem cell or cancer progenitor properties. Cancer Res 71(3): 716-724.
  56. Smith, B. H., Gazda, L. S., Conn, B. L., Jain, K., Asina, S., Levine, D. M., Parker, T. S., Laramore, M. A., Martis, P. C., Vinerean, H. V., David, E. M., Qiu, S., North, A. J., Couto, C. G., Post, G. S., Waters, D. J., Cordon-Cardo, C., Hall, R. D., Gordon, B. R., Diehl, C. H., Stenzel, K. H. and Rubin, A. L. (2011). Hydrophilic agarose macrobead cultures select for outgrowth of carcinoma cell populations that can restrict tumor growth. Cancer Res 71(3): 725-735.
  57. Lunardi, A., Gaboli, M., Giorgio, M., Rivi, R., Bygrave, A., Antoniou, M., Drabek, D., Dzierzak, E., Fagioli, M., Salmena, L., Botto, M., Cordon-Cardo, C., Luzzatto, L., Pelicci, P. G., Grosveld, F. and Pandolfi, P. P. (2011). A Role for PML in Innate Immunity. Genes Cancer 2(1): 10-19.
  58. Kim, I. Y., Yan, X., Tohme, S., Ahmed, A., Cordon-Cardo, C., Shantha Kumara, H. M., Kim, S. K. and Whelan, R. L. (2012). CpG ODN, Toll like receptor (TLR)-9 agonist, inhibits metastatic colon adenocarcinoma in a murine hepatic tumor model. J Surg Res 174(2): 284-290.
  59. Charytonowicz, E., Matushansky, I., Castillo-Martin, M., Hricik, T., Cordon-Cardo, C. and Ziman, M. (2011). Alternate PAX3 and PAX7 C-terminal isoforms in myogenic differentiation and sarcomagenesis. Clin Transl Oncol 13(3): 194-203.
  60. Wosnitzer, M. S., Hruby, G. W., Murphy, A. M., Barlow, L. J., Cordon-Cardo, C., Mansukhani, M., Petrylak, D. P., Benson, M. C. and McKiernan, J. M. (2012). A comparison of the outcomes of neoadjuvant and adjuvant chemotherapy for clinical T2-T4aN0-N2M0 bladder cancer. Cancer 118(2): 358-364.
  61. Cebrian, V., Fierro, M., Orenes-Pinero, E., Grau, L., Moya, P., Ecke, T., Alvarez, M., Gil, M., Algaba, F., Bellmunt, J., Cordon-Cardo, C., Catto, J., Lopez-Beltran, A. and Sanchez-Carbayo, M. (2011). KISS1 methylation and expression as tumor stratification biomarkers and clinical outcome prognosticators for bladder cancer patients. Am J Pathol 179(2): 540-546.
  62. Chen, M., Pratt, C. P., Zeeman, M. E., Schultz, N., Taylor, B. S., O'Neill, A., Castillo-Martin, M., Nowak, D. G., Naguib, A., Grace, D. M., Murn, J., Navin, N., Atwal, G. S., Sander, C., Gerald, W. L., Cordon-Cardo, C., Newton, A. C., Carver, B. S. and Trotman, L. C. (2011). Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer Cell 20(2): 173-186.
  63. Wosnitzer, M. S., Domingo-Domenech, J., Castillo-Martin, M., Ritch, C., Mansukhani, M., Petrylack, D. P., Benson, M. C., McKiernan, J. M. and Cordon-Cardo, C. (2011). Predictive value of microtubule associated proteins tau and stathmin in patients with nonmuscle invasive bladder cancer receiving adjuvant intravesical taxane therapy. J Urol 186(5): 2094-2100.
Protocols by Carlos Cordon-Cardo
  1. In vivo Bioluminescence Imaging of Luciferase-labeled Cancer Cells