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Ilgen Mender

Education

Ph.D. in Biochemistry Program, University of Texas Southwestern Medical Center, Department of Cell Biology, Shay/Wright Lab, Dallas, Texas, USA, 2014

Current position

Postdoctoral Researcher in Postdoctoral Scholar Program for Certificate in Research, University of Texas Southwestern Medical Center, Department of Cell Biology, Shay/Wright Lab, Dallas, Texas, USA (2015-present)
Advisor: Jerry W. Shay, Ph.D.

Publications

Peer-Reviewed Journal Articles

  1. Mender, I., Gryaznov, S., Dikmen, Z. G., Wright, W. E. and Shay, J. W. (2015). Induction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2'-deoxyguanosine. Cancer Discov 5(1): 82-95.
  2. Hosler, G. A., Davoli, T., Mender, I., Litzner, B., Choi, J., Kapur, P., Shay, J. W. and Wang, R. C. (2015). A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT. J Cutan Pathol 42(2): 108-117.
  3. Mender, I., Senturk, S., Ozgunes, N., Akcali, K. C., Kletsas, D., Gryaznov, S., Can, A., Shay, J. W. and Dikmen, Z. G. (2013). Imetelstat (a telomerase antagonist) exerts offtarget effects on the cytoskeleton. Int J Oncol 42(5): 1709-1715.

Invited Reviews/Book Chapter/Protocol Journal

  1. Mender, I., Gryaznov, S. and Shay, J. W. (2015). A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells. Oncoscience 2(8): 693-695. (Research Perspective)
  2. Mender I., Dikmen ZG., Shay JW. Cancer cell immortality: targeting telomerase. Cancer Medicine, in press (Book Chapter).
  3. Mender I., Dikmen ZG., Dogan P. Diseases related with dysfunctional telomeres. Hacettepe Medical Journal, 2008; 39(4), 163-167 (Review).
Protocols by Ilgen Mender
  1. Telomere Dysfunction Induced Foci (TIF) Analysis
  2. Telomerase Repeated Amplification Protocol (TRAP)
  3. Telomere Restriction Fragment (TRF) Analysis