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Maria Li Lung

Education

BS, Microbiology, Cornell University, Ithaca, New York, USA, 1974. PhD, Medical Microbiology, Cancer Biology Research Laboratory, Stanford University, Stanford, California, USA, 1978

Current position

Chair Professor of Department of Clinical Oncology, Director of Laboratory of Cancer Molecular Genomics, University of Hong Kong, Hong Kong. Director, Center for Nasopharyngeal Carcinoma Research (2010-2018)

Publications

  1. Lung, H. L., Cheung, A. K., Ko, J. M., Cheng, Y., Stanbridge, E. J. and Lung, M. L. (2012). Deciphering the molecular genetic basis of NPC through functional approaches. Semin Cancer Biol 22(2): 87-95.
  2. Lung, M. L. (2012). Unlocking the Rosetta Stone enigma for nasopharyngeal carcinoma: genetics, viral infection, and epidemiological factors. Semin Cancer Biol 22(2): 77-78.
  3. Cheung, A. K., Ko, J. M., Lung, H. L., Chan, K. W., Stanbridge, E. J., Zabarovsky, E., Tokino, T., Kashima, L., Suzuki, T., Kwong, D. L., Chua, D., Tsao, S. W. and Lung, M. L. (2011). Cysteine-rich intestinal protein 2 (CRIP2) acts as a repressor of NF-kappaB-mediated proangiogenic cytokine transcription to suppress tumorigenesis and angiogenesis. Proc Natl Acad Sci U S A 108(20): 8390-8395.
  4. Lo, P. H., Lung, H. L., Cheung, A. K., Apte, S. S., Chan, K. W., Kwong, F. M., Ko, J. M., Cheng, Y., Law, S., Srivastava, G., Zabarovsky, E. R., Tsao, S. W., Tang, J. C., Stanbridge, E. J. and Lung, M. L. (2010). Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis. Cancer Res 70(13): 5567-5576.
  5. Cheung, A. K., Lung, H. L., Ko, J. M., Cheng, Y., Stanbridge, E. J., Zabarovsky, E. R., Nicholls, J. M., Chua, D., Tsao, S. W., Guan, X. Y. and Lung, M. L. (2009). Chromosome 14 transfer and functional studies identify a candidate tumor suppressor gene, mirror image polydactyly 1, in nasopharyngeal carcinoma. Proc Natl Acad Sci U S A 106(34): 14478-14483.
  6. Cheung, A. K., Lung, H. L., Hung, S. C., Law, E. W., Cheng, Y., Yau, W. L., Bangarusamy, D. K., Miller, L. D., Liu, E. T., Shao, J. Y., Kou, C. W., Chua, D., Zabarovsky, E. R., Tsao, S. W., Stanbridge, E. J. and Lung, M. L. (2008). Functional analysis of a cell cycle-associated, tumor-suppressive gene, protein tyrosine phosphatase receptor type G, in nasopharyngeal carcinoma. Cancer Res 68(19): 8137-8145.
  7. Lung, H. L., Cheung, A. K., Xie, D., Cheng, Y., Kwong, F. M., Murakami, Y., Guan, X. Y., Sham, J. S., Chua, D., Protopopov, A. I., Zabarovsky, E. R., Tsao, S. W., Stanbridge, E. J. and Lung, M. L. (2006). TSLC1 is a tumor suppressor gene associated with metastasis in nasopharyngeal carcinoma. Cancer Res 66(19): 9385-9392.
  8. Cheng, Y., Poulos, N. E., Lung, M. L., Hampton, G., Ou, B., Lerman, M. I. and Stanbridge, E. J. (1998). Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3. Proc Natl Acad Sci U S A 95(6): 3042-3047.
Protocols by Maria Li Lung
  1. In vitro Human Umbilical Vein Endothelial Cells (HUVEC) Tube-formation Assay
  2. In vivo Matrigel Plug Angiogenesis Assay
  3. Subcellular Fractionation of Cultured Human Cell Lines