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Wei Zheng


Ph.D. in Genetics, Laboratory of Genetics, University of Wisconsin-Madison, 2007

Current position

She is an associate research scientist in Keck Biostatistics Resources at Yale University. Her research focuses on population genetics and genomics.


  1. Guan, Q.*, Zheng, W.*, Tang, S.*, Liu, X., Zinkel, R. A., Tsui, K. W., Yandell, B. S. and Culbertson, M. R. (2006). Impact of nonsense-mediated mRNA decay on the global expression profile of budding yeast. PLoS Genet 2(11): e203. * co-first authors.
  2. Zheng, W., Finkel, J. S., Landers, S. M., Long, R. M. and Culbertson, M. R. (2008). Nonsense-mediated decay of ash1 nonsense transcripts in Saccharomyces cerevisiae. Genetics 180(3): 1391-1405.
  3. Lefrancois, P., Zheng, W. and Snyder, M. (2010). ChIP-Seq using high-throughput DNA sequencing for genome-wide identification of transcription factor binding sites. Methods Enzymol 470: 77-104.
  4. Zheng, W., Zhao, H., Mancera, E., Steinmetz, L. M. and Snyder, M. (2010). Genetic analysis of variation in transcription factor binding in yeast. Nature 464(7292): 1187-1191.
  5. Li, L.*, Zheng, W.*, Lee, J. S.*, Zhang, X., Ferguson, J., Yan, X. and Zhao, H. (2011). Collapsing-based and kernel-based single-gene analyses applied to Genetic Analysis Workshop 17 mini-exome data. BMC Proc 5(Suppl 9 Genetic Analysis Workshop 17: Unraveling Human Exome DataS Ghosh, H Bickeboller, J Bailey, JE Bailey-Wilson, R Cantor, W Daw, AL DeStefano, CD Engelman, A Hinrichs, J Houwing-Duistermaat, IR Konig, J Kent Jr., N Pankratz, A Paterson, E Pugh, Y Sun, A Thomas, N Tintle, X Zhu, JW MacCluer and L Almasy): S117. * co-first authors.
  6. Kang, J., Zheng, W., Li, L., Lee, J. S., Yan, X. and Zhao, H. (2011). Use of Bayesian networks to dissect the complexity of genetic disease: application to the Genetic Analysis Workshop 17 simulated data. BMC Proc 5 Suppl 9: S37.
  7. Li, G., Ferguson, J., Zheng, W., Lee, J. S., Zhang, X., Li, L., Kang, J., Yan, X. and Zhao, H. (2011). Large-scale risk prediction applied to Genetic Analysis Workshop 17 mini-exome sequence data. BMC Proc 5 Suppl 9: S46.
  8. Yan, X., Li, L., Lee, J. S., Zheng, W., Ferguson, J. and Zhao, H. (2011). Detecting functional rare variants by collapsing and incorporating functional annotation in Genetic Analysis Workshop 17 mini-exome data. BMC Proc 5 Suppl 9: S27.
  9. Zheng, W., Gianoulis, T. A., Karczewski, K. J., Zhao, H. and Snyder, M. (2011). Regulatory variation within and between species. Annu Rev Genomics Hum Genet 12: 327-346.
Protocols by Wei Zheng
  1. Illumina Sequencing Library Construction from ChIP DNA
  2. [Bio101] Yeast Transcription Factor Chromatin Immunoprecipitation
  3. [Bio101] Yeast in situ Hybridization
  4. [Bio101] qPCR of Yeast ChIP DNA
  5. [Bio101] Preparation of Taq DNA Polymerase
  6. [Bio101] RNA Extraction from Yeast
  7. [Bio101] Polyribosome Profiling