Micheline Guillotte
  • Institut Pasteur
Research fields
  • Microbiology
Personal information

Education

Degree from the Ecole Pratique des Hautes Etudes in Paris. Ministry of National Education, 1986

Current position

Engineer 2 at Institut Pasteur, Paris

Publications

  1. Filippone, C., Bassot, S., Betsem, E., Tortevoye, P., Guillotte, M., Mercereau-Puijalon, O., Plancoulaine, S., Calattini, S. and Gessain, A. (2012). A new and frequent human T-cell leukemia virus indeterminate Western blot pattern: epidemiological determinants and PCR results in central African inhabitants. J Clin Microbiol 50(5): 1663-1672.
  2. Vigan-Womas, I., Guillotte, M., Juillerat, A., Hessel, A., Raynal, B., England, P., Cohen, J. H., Bertrand, O., Peyrard, T., Bentley, G. A., Lewit-Bentley, A. and Mercereau-Puijalon, O. (2012). Structural basis for the ABO blood-group dependence of Plasmodium falciparum rosetting. PLoS Pathog 8(7): e1002781.
  3. Migot-Nabias, F., Lokossou, A. G., Vigan-Womas, I., Guitard, E., Guillotte, M., Noukpo, J. M., Mercereau-Puijalon, O., Dugoujon, J. M. and Garcia, A. (2011). Combined effects of Gm or Km immunoglobulin allotypes and age on antibody responses to Plasmodium falciparum VarO rosetting variant in Benin. Microbes Infect 13(8-9): 771-775.
  4. Janes, J. H., Wang, C. P., Levin-Edens, E., Vigan-Womas, I., Guillotte, M., Melcher, M., Mercereau-Puijalon, O. and Smith, J. D. (2011). Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family. PLoS Pathog 7(5): e1002032.
  5. Deplaine, G., Lavazec, C., Bischoff, E., Natalang, O., Perrot, S., Guillotte-Blisnick, M., Coppee, J. Y., Pradines, B., Mercereau-Puijalon, O. and David, P. H. (2011). Artesunate tolerance in transgenic Plasmodium falciparum parasites overexpressing a tryptophan-rich protein. Antimicrob Agents Chemother 55(6): 2576-2584.
  6. Juillerat, A., Lewit-Bentley, A., Guillotte, M., Gangnard, S., Hessel, A., Baron, B., Vigan-Womas, I., England, P., Mercereau-Puijalon, O. and Bentley, G. A. (2011). Structure of a Plasmodium falciparum PfEMP1 rosetting domain reveals a role for the N-terminal segment in heparin-mediated rosette inhibition. Proc Natl Acad Sci U S A 108(13): 5243-5248.
  7. Vigan-Womas, I., Guillotte, M., Juillerat, A., Vallieres, C., Lewit-Bentley, A., Tall, A., Baril, L., Bentley, G. A. and Mercereau-Puijalon, O. (2011). Allelic diversity of the Plasmodium falciparum erythrocyte membrane protein 1 entails variant-specific red cell surface epitopes. PLoS ONE 6(1): e16544.
  8. Deplaine, G., Safeukui, I., Jeddi, F., Lacoste, F., Brousse, V., Perrot, S., Biligui, S., Guillotte, M., Guitton, C., Dokmak, S., Aussilhou, B., Sauvanet, A., Cazals Hatem, D., Paye, F., Thellier, M., Mazier, D., Milon, G., Mohandas, N., Mercereau-Puijalon, O., David, P. H. and Buffet, P. A. (2011). The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro. Blood 117(8): e88-95.
  9. Vigan-Womas, I., Lokossou, A., Guillotte, M., Juillerat, A., Bentley, G., Garcia, A., Mercereau-Puijalon, O. and Migot-Nabias, F. (2010). The humoral response to Plasmodium falciparum VarO rosetting variant and its association with protection against malaria in Beninese children. Malar J 9: 267.
  10. Juillerat, A., Igonet, S., Vigan-Womas, I., Guillotte, M., Gangnard, S., Faure, G., Baron, B., Raynal, B., Mercereau-Puijalon, O. and Bentley, G. A. (2010). Biochemical and biophysical characterisation of DBL1alpha1-varO, the rosetting domain of PfEMP1 from the VarO line of Plasmodium falciparum. Mol Biochem Parasitol 170(2): 84-92.
  11. Noranate, N., Prugnolle, F., Jouin, H., Tall, A., Marrama, L., Sokhna, C., Ekala, M. T., Guillotte, M., Bischoff, E., Bouchier, C., Patarapotikul, J., Ohashi, J., Trape, J. F., Rogier, C. and Mercereau-Puijalon, O. (2009). Population diversity and antibody selective pressure to Plasmodium falciparum MSP1 block2 locus in an African malaria-endemic setting. BMC Microbiol 9: 219.
  12. Vigan-Womas, I., Guillotte, M., Le Scanf, C., Igonet, S., Petres, S., Juillerat, A., Badaut, C., Nato, F., Schneider, A., Lavergne, A., Contamin, H., Tall, A., Baril, L., Bentley, G. A. and Mercereau-Puijalon, O. (2008). An in vivo and in vitro model of Plasmodium falciparum rosetting and autoagglutination mediated by varO, a group A var gene encoding a frequent serotype. Infect Immun 76(12): 5565-5580.
  13. Mercereau-Puijalon, O., Guillotte, M. and Vigan-Womas, I. (2008). Rosetting in Plasmodium falciparum: a cytoadherence phenotype with multiple actors. Transfus Clin Biol 15(1-2): 62-71.
  14. Le Scanf, C., Vigan-Womas, I., Contamin, H., Guillotte, M., Bischoff, E. and Mercereau-Puijalon, O. (2008). Rosetting is associated with increased Plasmodium falciparum in vivo multiplication rate in the Saimiri sciureus monkey. Microbes Infect 10(4): 447-451.
  15. Noranate, N., Durand, R., Tall, A., Marrama, L., Spiegel, A., Sokhna, C., Pradines, B., Cojean, S., Guillotte, M., Bischoff, E., Ekala, M. T., Bouchier, C., Fandeur, T., Ariey, F., Patarapotikul, J., Le Bras, J., Trape, J. F., Rogier, C. and Mercereau-Puijalon, O. (2007). Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use. PLoS ONE 2(1): e139.
  16. Legrand, E., Volney, B., Lavergne, A., Tournegros, C., Florent, L., Accrombessi, D., Guillotte, M., Mercereau-Puijalon, O. and Esterre, P. (2005). Molecular analysis of two local falciparum malaria outbreaks on the French Guiana coast confirms the msp1 B-K1/varD genotype association with severe malaria. Malar J 4: 26.
  17. Silva, M. D., Cooke, B. M., Guillotte, M., Buckingham, D. W., Sauzet, J. P., Le Scanf, C., Contamin, H., David, P., Mercereau-Puijalon, O. and Bonnefoy, S. (2005). A role for the Plasmodium falciparum RESA protein in resistance against heat shock demonstrated using gene disruption. Mol Microbiol 56(4): 990-1003.
  18. Rogier, C., Tall, A., Faye, J., Guillote, M., Blanc, C., Trape, J. F., Spiegel, A., Marrama, L., Nabeth, P., Fontenille, D., Druilhe, P. and Puijalon, O. (2003). [Cohorts and bio-libraries for studying malaria in tropical areas]. Rev Epidemiol Sante Publique 51(1 Pt 2): 175-182.
  19. Perraut, R., Guillotte, M., Drame, I., Diouf, B., Molez, J. F., Tall, A., Trape, J. F., Mercereau-Puijalon, O., Spiegel, A. and Garraud, O. (2002). Evaluation of anti-Plasmodium falciparum antibodies in Senegalese adults using different types of crude extracts from various strains of parasite. Microbes Infect 4(1): 31-35.
  20. Perraut,R., Moralès-Betoulle, S., Le Scanf, C., Bourreau, E., Guillotte M., Michel, J.C. & Mercereau-Puijalon O. (2001). Evaluation of immunogenicity and protective efficacy of carrier-free Plasmodium falciparum R23 antigen in pre-exposed Saimiri sciureus monkeys. Vaccine 19: 59-67.
  21. Mahieux, R., Horal, P., Mauclere, P., Mercereau-Puijalon, O., Guillotte, M., Meertens, L., Murphy, E. and Gessain, A. (2000). Human T-cell lymphotropic virus type 1 gag indeterminate western blot patterns in Central Africa: relationship to Plasmodium falciparum infection. J Clin Microbiol 38(11): 4049-4057.
  22. Bischoff, E., Guillotte, M., Mercereau-Puijalon, O. and Bonnefoy, S. (2000). A member of the Plasmodium falciparum Pf60 multigene family codes for a nuclear protein expressed by readthrough of an internal stop codon. Mol Microbiol 35(5): 1005-1016.
  23. Le Scanf, C., Fandeur, T., Bonnefoy, S., Guillotte, M. and Mercereau-Puijalon, O. (1999). Novel target antigens of the variant-specific immune response to Plasmodium falciparum identified by differential screening of an expression library. Infect Immun 67(1): 64-73.
  24. Le Scanf, C., Fandeur, T., Bonnefoy, S., Guillotte, M. and Mercereau-Puijalon, O. (1999). Novel target antigens of the variant-specific immune response to Plasmodium falciparum identified by differential screening of an expression library. Infect Immun 67(1): 64-73.
  25. Bonnefoy, S., Bischoff, E., Guillotte, M. and Mercereau-Puijalon, O. (1997). Evidence for distinct prototype sequences within the Plasmodium falciparum Pf60 multigene family. Mol Biochem Parasitol 87(1): 1-11.
  26. Carcy, B., Bonnefoy, S., Guillotte, M., Le Scanf, C., Grellier, P., Schrevel, J., Fandeur, T. and Mercereau-Puijalon, O. (1994). A large multigene family expressed during the erythrocytic schizogony of Plasmodium falciparum. Mol Biochem Parasitol 68(2): 221-233.
  27. Bonnefoy, S., Gysin, J., Blisnick, T., Guillotte, M., Carcy, B., Pereira da Silva, L. and Mercereau-Puijalon, O. (1994). Immunogenicity and antigenicity of a Plasmodium falciparum protein fraction (90-110 kDa) able to protect squirrel monkeys against asexual blood stages. Vaccine 12(1): 32-40.
  28. Bonnefoy, S., Guillotte, M., Langsley, G. and Mercereau-Puijalon, O. (1992). Plasmodium falciparum: characterization of gene R45 encoding a trophozoite antigen containing a central block of six amino acid repeats. Exp Parasitol 74(4): 441-451.
  29. Mercereau-Puijalon, O., Guillotte, M. and Doyen, N. (1992). Cross-reaction of antibodies to the nine-amino acid repeats of Plasmodium falciparum antigen 11.1 with human serum albumin. Eur J Immunol 22(2): 381-385.
  30. Mercereau-Puijalon, O., Fandeur, T., Guillotte, M. and Bonnefoy, S. (1991). Parasite features impeding malaria immunity: antigenic diversity, antigenic variation and poor immunogenicity. Res Immunol 142(8): 690-697.
  31. Mattei, D., Berzins, K., Wahlgren, M., Udomsangpetch, R., Perlmann, P., Griesser, H. W., Scherf, A., Muller-Hill, B., Bonnefoy, S., Guillotte, M. and et al. (1989). Cross-reactive antigenic determinants present on different Plasmodium falciparum blood-stage antigens. Parasite Immunol 11(1): 15-29.
  32. Bonnefoy, S., Mattei, D., Dubremetz, J. F., Guillotte, M., Jouin, H., Ozaki, L. S., Sibilli, L. and Mercereau-Puijalon, O. (1988). Plasmodium falciparum: molecular analysis of a putative protective antigen, the thermostable 96-kDa protein. Exp Parasitol 65(1): 69-83.
  33. Mattei, D., Langsley, G., Braun-Breton, C., Guillotte, M., Dubremetz, J. F. and Mercereau-Puijalon, O. (1988). The S-antigen of Plasmodium falciparum Palo Alto represents a new S-antigen serotype. Mol Biochem Parasitol 27(2-3): 171-180.
  34. Kahane, B., Sibilli, L., Scherf, A., Jaureguiberry, G., Langsley, G., Ozaki, L. S., Guillotte, M., Muller-Hill, B., Pereira da Silva, L. and Mercereau-Puijalon, O. (1987). The polymorphic 11.1 locus of Plasmodium falciparum. Mol Biochem Parasitol 26(1-2): 77-85.
  35. Mercereau-Puijalon, O., Langsley, G., Mattei, D., Guillotte M., Blisnick, T., Berzins, K., Griesser, H.W., Scherf, A., Muller-Hill, B. and Pereira Da Silva, L. (1987). Presence of cross reacting on several blood stage antigens of Plasmodium falciparum. Molecular Strategies of parasitic invasion UCLA Symposia and Molecular and Cellular Biology, New Series, 42, (N. Agabian,H. ,Goodman, N. Nogueira.,ed.) Alan R Liss,New York, 343-354.
  36. Mercereau-Puijalon, O., Blisnick, T., Fandeur, T., Dedet, J. P., Roussilhon, C., Guillotte, M., Kahane, B., Breton, C., Siffert, O., Griesser, H. W. and et al. (1986). Immunogenicity of Plasmodium falciparum antigenic determinants produced by Escherichia coli recombinant clones. Ann Inst Pasteur Immunol 137D(1): 63-78.
  37. Ozaki, L. S., Mattei, D., Jendoubi, M., Druihle, P., Blisnick, T., Guillotte, M., Puijalon, O. and Da Silva, L. P. (1986). Plaque antibody selection: rapid immunological analysis of a large number of recombinant phage clones positive to sera raised against Plasmodium falciparum antigens. J Immunol Methods 89(2): 213-219.
  38. Guillotte M.(1986). Dipl?me de l'Ecole Pratique des Hautes Etudes "Clonage de gènes codant pour les antigènes de Plasmoduim falciparum, analyse de deux antigènes des stades érytthrocytaires".
  39. Langsley, G., Scherf, A., Mercereau-Puijalon, O., Koenen, M., Kahane, B., Mattei, D., Guillotte, M., Sibilli, L., Garner, I., Muller-Hill, B. and et al. (1985). Characterisation of P. falciparum antigenic determinants isolated from a genomic expression library by differential antibody screening. Nucleic Acids Res 13(11): 4191-4202.
  40. Nivet, C., Guillotte, M. and Pereira da Silva, L. (1983). Plasmodium falciparum: one-step growth in a semi-defined medium and the stimulatory effect of human seric lipoproteins and liposomes. Exp Parasitol 55(1): 147-151.
  41. Hommel, M., David, P. H., Guillotte, M. and Pereira da Silva, L. (1982). Protection against Plasmodium chabaudi malaria. I.--Vaccination of mice with merozoites and Freund's adjuvants. Ann Immunol (Paris) 133C(1): 57-67.
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