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Immunology

Infant Rabbit Colonization Competition Assays

Authors: Yang Fu
Yang FuAffiliation: Department of Microbiology and Immunobiology, Harvard Medical School, Boston, USA
For correspondence: yang_fu@hms.harvard.edu
Bio-protocol author page: a1395
 and John J. Mekalanos
John J. MekalanosAffiliation: Department of Microbiology and Immunobiology, Harvard Medical School, Boston, USA
For correspondence: john_mekalanos@hms.harvard.edu
Bio-protocol author page: a1396
date: 6/5/2014, 3058 views, 0 Q&A
DOI: https://doi.org/10.21769/BioProtoc.1147.

[Abstract] Enteric pathogenic bacteria such as Vibrio cholerae and enteropathogenic Escherichia coli (E. coli) cause life-threatening diarrheal diseases that have afflicted humans for centuries. Understanding the effectors required for intestinal colonization is very important to research on bacteria pathogenesis, and is also important to testing new therapeutics ...

Gastric Aspiration Models

Authors: Bruce A. Davidson
Bruce A. DavidsonAffiliation: Department of Anesthesiology, and Pathology and Anatomical Sciences, State University of New York at Buffalo, Buffalo, USA
For correspondence: bdavidso@buffalo.edu
Bio-protocol author page: a1019
 and Ravi Alluri
Ravi AlluriAffiliation: Department of Anesthesiology, and Pathology and Anatomical Sciences, State University of New York at Buffalo, Buffalo, USA
Bio-protocol author page: a1020
date: 11/20/2013, 7440 views, 0 Q&A
DOI: https://doi.org/10.21769/BioProtoc.968.

[Abstract] The procedures described below are for producing gastric aspiration pneumonitis in mice with alterations for rats and rabbits described parenthetically. We use 4 different injury vehicles delivered intratracheally to investigate the inflammatory responses to gastric aspiration:
1) Normal saline (NS) as the injury vehicle control
2) NS + HCl, pH = 1.25 ...

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Gastric Aspiration Models

Authors: Bruce A. Davidson
Bruce A. DavidsonAffiliation: Department of Anesthesiology, and Pathology and Anatomical Sciences, State University of New York at Buffalo, Buffalo, USA
For correspondence: bdavidso@buffalo.edu
Bio-protocol author page: a1019
 and Ravi Alluri
Ravi AlluriAffiliation: Department of Anesthesiology, and Pathology and Anatomical Sciences, State University of New York at Buffalo, Buffalo, USA
Bio-protocol author page: a1020
date: 11/20/2013, 7440 views, 0 Q&A
DOI: https://doi.org/10.21769/BioProtoc.968.

[Abstract] The procedures described below are for producing gastric aspiration pneumonitis in mice with alterations for rats and rabbits described parenthetically. We use 4 different injury vehicles delivered intratracheally to investigate the inflammatory responses to gastric aspiration:
1) Normal saline (NS) ...

Infant Rabbit Colonization Competition Assays

Authors: Yang Fu
Yang FuAffiliation: Department of Microbiology and Immunobiology, Harvard Medical School, Boston, USA
For correspondence: yang_fu@hms.harvard.edu
Bio-protocol author page: a1395
 and John J. Mekalanos
John J. MekalanosAffiliation: Department of Microbiology and Immunobiology, Harvard Medical School, Boston, USA
For correspondence: john_mekalanos@hms.harvard.edu
Bio-protocol author page: a1396
date: 6/5/2014, 3058 views, 0 Q&A
DOI: https://doi.org/10.21769/BioProtoc.1147.

[Abstract] Enteric pathogenic bacteria such as Vibrio cholerae and enteropathogenic Escherichia coli (E. coli) cause life-threatening diarrheal diseases that have afflicted humans for centuries. Understanding the effectors required for intestinal colonization is very important to research on bacteria pathogenesis, ...
1