Welcome guest, Login | Register


Mingfang Lu


Ph.D. in Immunology,  UT-Southwestern Medical Center at Dallas, Dallas, TX, 2003

Current Position

Investigator, Department of Immunology, Shanghai Medical College, Fudan University, Shanghai, 200032, China


  1. Huang, Y. L., Morales-Rosado, J., Ray, J., Myers, T. G., Lu, M. and Munford, R. S. Toll-like receptor (TLR) 1/2 and 4 agonists prolong triglyceride retention in macrophages. Submitted
  2. Janelsin, B. M., Myles, I. A., Lu, M. and Datta, S. K. Altered LPS inactivation due to acyloxyacyl hydrolase deficiency in colonic lamina propria dendritic cells impairs mucosal Th17 immunity.Submitted
  3. Lu, M., Varley, A. W. and Munford, R. S. (2013). Persistently active microbial molecules prolong innate immune tolerance in vivo. PLoS Pathog 9(5): e1003339.
  4. Lu, M. and Munford, R. S. (2011). The transport and inactivation kinetics of bacterial lipopolysaccharide influence its immunological potency in vivo. J Immunol 187(6): 3314-3320.
  5. Munford, R., Lu, M. and Varley, A. (2009). Chapter 2: Kill the bacteria...and also their messengers? Adv Immunol 103: 29-48.
  6. Lu, M., Varley, A. W., Ohta, S., Hardwick, J. and Munford, R. S. (2008). Host inactivation of bacterial lipopolysaccharide prevents prolonged tolerance following gram-negative bacterial infection. Cell Host Microbe 4(3): 293-302.
  7. Shao, B., Lu, M., Katz, S. C., Varley, A. W., Hardwick, J., Rogers, T. E., Ojogun, N., Rockey, D. C., Dematteo, R. P. and Munford, R. S. (2007). A host lipase detoxifies bacterial lipopolysaccharides in the liver and spleen. J Biol Chem 282(18): 13726-13735.
  8. Lu, M., Zhang, M., Takashima, A., Weiss, J., Apicella, M. A., Li, X. H., Yuan, D. and Munford, R. S. (2005). Lipopolysaccharide deacylation by an endogenous lipase controls innate antibody responses to Gram-negative bacteria. Nat Immunol 6(10): 989-994.
  9. Feulner, J. A., Lu, M., Shelton, J. M., Zhang, M., Richardson, J. A. and Munford, R. S. (2004). Identification of acyloxyacyl hydrolase, a lipopolysaccharide-detoxifying enzyme, in the murine urinary tract. Infect Immun 72(6): 3171-3178.
  10. Lu, M., Zhang, M., Kitchens, R. L., Fosmire, S., Takashima, A. and Munford, R. S. (2003). Stimulus-dependent deacylation of bacterial lipopolysaccharide by dendritic cells. J Exp Med 197(12): 1745-1754.
  11. Lu, M. and Jiang, W. D. (1996).Pharmacokinetics of Imported Nisoldipine in Chinese Healthy Volunteers. Chinese Journal of Clinical Pharmacology. 12:93-98
Protocols by Mingfang Lu
  1. Harvest and Culture of Mouse Peritoneal Macrophages