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Jonathan B. Weitzman


Ph.D. in Biochemistry and Molecular Biology, University of Oxford, Oxford, UK

Current position

Director, UMR7216 Epigenetics and Cell Fate, CNRS/Université Paris-Diderot, France

Professor, Université Paris-Diderot, France

Publications (since 2005)

  1. Medjkane, S. and Weitzman, J. B. (2013). A reversible Warburg effect is induced by Theileria parasites to transform host leukocytes. Cell Cycle 12(14): 2167-2168.
  2. Medjkane, S., Perichon, M., Marsolier, J., Dairou, J. and Weitzman, J. B. (2013). Theileria induces oxidative stress and HIF1α activation that are essential for host leukocyte transformation. Oncogene.
  3. Marsolier, J., Pineau, S., Medjkane, S., Perichon, M., Yin, Q., Flemington, E., Weitzman, M. D. and Weitzman, J. B. (2013). OncomiR addiction is generated by a miR-155 feedback loop in Theileria-transformed leukocytes. PLoS Pathog 9(4): e1003222.
  4. Cock-Rada, A. and Weitzman, J. B. (2013). The methylation landscape of tumour metastasis. Biol Cell 105(2): 73-90.
  5. Weitzman, J. (2012). Epigenetics in health and disease. Joint Bone Spine 79(6): 565.
  6. Hafner, S. and Weitzman, J. (2012). Of mice and men--NAIP homologues face Legionella pneumophila. Microbes Infect 14(13): 1119-1122.
  7. Medjkane, S., Cock-Rada, A. and Weitzman, J. B. (2012). Role of the SMYD3 histone methyltransferase in tumorigenesis: local or global effects? Cell Cycle 11(10): 1865.
  8. Cock-Rada, A. M., Medjkane, S., Janski, N., Yousfi, N., Perichon, M., Chaussepied, M., Chluba, J., Langsley, G. and Weitzman, J. B. (2012). SMYD3 promotes cancer invasion by epigenetic upregulation of the metalloproteinase MMP-9. Cancer Res 72(3): 810-820.
  9. Chaussepied, M., Janski, N., Baumgartner, M., Lizundia, R., Jensen, K., Weir, W., Shiels, B. R., Weitzman, J. B., Glass, E. J., Werling, D. and Langsley, G. (2010). TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility. PLoS Pathog 6(11): e1001197.
  10. Marden, J. J., Zhang, Y., Oakley, F. D., Zhou, W., Luo, M., Jia, H. P., McCray, P. B., Jr., Yaniv, M., Weitzman, J. B. and Engelhardt, J. F. (2008). JunD protects the liver from ischemia/reperfusion injury by dampening AP-1 transcriptional activation. J Biol Chem 283(11): 6687-6695.
  11. Verde, P., Casalino, L., Talotta, F., Yaniv, M. and Weitzman, J. B. (2007). Deciphering AP-1 function in tumorigenesis: fra-ternizing on target promoters. Cell Cycle 6(21): 2633-2639.
  12. Wisniewska, M. B., Ameyar-Zazoua, M., Bakiri, L., Kaminska, B., Yaniv, M. and Weitzman, J. B. (2007). Dimer composition and promoter context contribute to functional cooperation between AP-1 and NFAT. J Mol Biol 371(3): 569-576.
  13. Lizundia, R., Chaussepied, M., Naissant, B., Masse, G. X., Quevillon, E., Michel, F., Monier, S., Weitzman, J. B. and Langsley, G. (2007). The JNK/AP-1 pathway upregulates expression of the recycling endosome rab11a gene in B cells transformed by Theileria. Cell Microbiol 9(8): 1936-1945.
  14. Casalino, L., Bakiri, L., Talotta, F., Weitzman, J. B., Fusco, A., Yaniv, M. and Verde, P. (2007). Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription. EMBO J 26(7): 1878-1890.
  15. Weitzman, J. B. (2006). Imaging with isotopes: high resolution and quantitation. J Biol 5(6): 17.
  16. Smart, D. E., Green, K., Oakley, F., Weitzman, J. B., Yaniv, M., Reynolds, G., Mann, J., Millward-Sadler, H. and Mann, D. A. (2006). JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation. Hepatology 44(6): 1432-1440.
  17. Weitzman, J. B. (2006). Getting the right dose of sex (chromosomes). J Biol 5(1): 1.
  18. Hilfiker-Kleiner, D., Hilfiker, A., Kaminski, K., Schaefer, A., Park, J. K., Michel, K., Quint, A., Yaniv, M., Weitzman, J. B. and Drexler, H. (2005). Lack of JunD promotes pressure overload-induced apoptosis, hypertrophic growth, and angiogenesis in the heart. Circulation 112(10): 1470-1477.
  19. Weitzman, J. B. (2005). A road map of yeast interactions. J Biol 4(2): 4.
  20. Miled, C., Pontoglio, M., Garbay, S., Yaniv, M. and Weitzman, J. B. (2005). A genomic map of p53 binding sites identifies novel p53 targets involved in an apoptotic network. Cancer Res 65(12): 5096-5104.
  21. Weitzman, J. B. (2005). Dishevelled nuclear shuttling. J Biol 4(1): 1.
  22. Ameyar-Zazoua, M., Wisniewska, M. B., Bakiri, L., Wagner, E. F., Yaniv, M. and Weitzman, J. B. (2005). AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene. Oncogene 24(14): 2298-2306.
Protocols by Jonathan B. Weitzman
  1. Ki67 Immunofluorescence on Bovine Cell Lines