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Longping V. Tse

Longping V. Tse


Ph.D. in Microbiology and Immunology, Cornell University, Ithaca, New York, 2013

Current position

Postdoctoral researcher, Gene Therapy Center, University of North Carolina at Chapel Hill (2014-present)


  1. Tse, L. V., Moller-Tank, S. and Asokan, A. (2015). Strategies to circumvent humoral immunity to adeno-associated viral vectors. Expert Opin Biol Ther 15(6): 845-855.   
  2. Tse, L. V., Zhang, Y. and Whittaker, G. R. (2013). Immunoplaque assay (influenza virus). Bio-protocol 3(21): e959.
  3. Feng, K. H., Gonzalez, G., Deng, L., Yu, H., Tse, V. L., Huang, L., Huang, K., Wasik, B. R., Zhou, B., Wentworth, D. E., Holmes, E. C., Chen, X., Varki, A., Murcia, P. R. and Parrish, C. R. (2015). Equine and Canine Influenza H3N8 Viruses Show Minimal Biological Differences Despite Phylogenetic Divergence. J Virol 89(13): 6860-6873.
  4. Tse, L. V. and Whittaker, G. R. (2015). Modification of the hemagglutinin cleavage site allows indirect activation of avian influenza virus H9N2 by bacterial staphylokinase. Virology 482: 1-8.
  5. Tse, L. V., Hamilton, A. M., Friling, T. and Whittaker, G. R. (2014). A novel activation mechanism of avian influenza virus H9N2 by furin. J Virol 88(3): 1673-1683. 
  6. Tse, L. V., Marcano, V. C., Huang, W., Pocwierz, M. S. and Whittaker, G. R. (2013). Plasmin-mediated activation of pandemic H1N1 influenza virus hemagglutinin is independent of the viral neuraminidase. J Virol 87(9): 5161-5169.
  7. Regan, A. D., Millet, J. K., Tse, L. P., Chillag, Z., Rinaldi, V. D., Licitra, B. N., Dubovi, E. J., Town, C. D. and Whittaker, G. R. (2012). Characterization of a recombinant canine coronavirus with a distinct receptor-binding (S1) domain. Virology 430(2): 90-99.
  8. Guo, H., Tse, L. V., Nieh, A. W., Czornyj, E., Williams, S., Oukil, S., Liu, V. B. and Miller, J. F. (2011). Target site recognition by a diversity-generating retroelement. PLoS Genet 7(12): e1002414.
  9. Sun, X., Tse, L. V., Ferguson, A. D. and Whittaker, G. R. (2010). Modifications to the hemagglutinin cleavage site control the virulence of a neurotropic H1N1 influenza virus. J Virol 84(17): 8683-8690.
  10. Guo, H., Tse, L. V., Barbalat, R., Sivaamnuaiphorn, S., Xu, M., Doulatov, S. and Miller, J. F. (2008). Diversity-generating retroelement homing regenerates target sequences for repeated rounds of codon rewriting and protein diversification. Mol Cell 31(6): 813-823.
Protocols by Longping V. Tse
  1. Immunoplaque Assay (Influenza Virus)
  2. Virus Binding and Internalization Assay for Adeno-associated Virus