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Ming Zeng


Ph.D. in Microbiology, Immunology and Cancer Biology program, University of Minnesota, Minneapolis, MN, 2012

Current position

Postdoctoral Research Fellow in Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center


  1. Wang, T., Zhan, X., Bu, C. H., Lyon, S., Pratt, D., Hildebrand, S., Choi, J. H., Zhang, Z. and Zeng, M. et al. (2015). Real‐time resolution of point mutations that cause phenovariance in mice. (Early edition)
  2. Zeng, M., Hu, Z., Shi, X., Li, X., Zhan, X., Li, X. D., Wang, J., Choi, J. H., Wang, K. W., Purrington, T., Tang, M., Fina, M., DeBerardinis, R. J., Moresco, E. M., Pedersen, G., McInerney, G. M., Hedestam, G. B., Chen, Z. J. and Beutler, B. (2014). MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses. Science 346(6216): 1486-1492.
  3. Li, Q.*, Zeng, M.*, Duan, L.*, Voss, J. E.*, Smith, A. J., Pambuccian, S., Shang, L., Wietgrefe, S., Southern, P. J., Reilly, C. S., Skinner, P. J., Zupancic, M. L., Carlis, J. V., Piatak, M., Jr., Waterman, D., Reeves, R. K., Masek-Hammerman, K., Derdeyn, C. A., Alpert, M. D., Evans, D. T., Kohler, H., Muller, S., Robinson, J., Lifson, J. D., Burton, D. R., Johnson, R. P. and Haase, A. T. (2014). Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry. J Immunol 193(6): 3113-3125. (*Co-first author) (Selected as the cover of this issue)
  4. Ko, S. Y., Pegu, A., Rudicell, R. S., Yang, Z. Y., Joyce, M. G., Chen, X., Wang, K., Bao, S., Kraemer, T. D., Rath, T., Zeng, M., Schmidt, S. D., Todd, J. P., Penzak, S. R., Saunders, K. O., Nason, M. C., Haase, A. T., Rao, S. S., Blumberg, R. S., Mascola, J. R. and Nabel, G. J. (2014). Enhanced neonatal Fc receptor function improves protection against primate SHIV infection. Nature 514(7524): 642-645.
  5. Zeng, M., Paiardini, M., Engram, J. C., Beilman, G. J., Chipman, J. G., Schacker, T. W., Silvestri, G. and Haase, A. T. (2012). Critical role of CD4 T cells in maintaining lymphoid tissue structure for immune cell homeostasis and reconstitution. Blood 120(9): 1856-1867.
  6. Zeng, M., Southern, P. J., Reilly, C. S., Beilman, G. J., Chipman, J. G., Schacker, T. W. and Haase, A. T. (2012). Lymphoid tissue damage in HIV-1 infection depletes naive T cells and limits T cell reconstitution after antiretroviral therapy. PLoS Pathog 8(1): e1002437.
  7. Zeng, M., Haase, A. T. and Schacker, T. W. (2012). Lymphoid tissue structure and HIV-1 infection: life or death for T cells. Trends Immunol 33(6): 306-314.
  8. Zeng, M.*, Smith, A. J.*, Wietgrefe, S. W., Southern, P. J., Schacker, T. W., Reilly, C. S., Estes, J. D., Burton, G. F., Silvestri, G., Lifson, J. D., Carlis, J. V. and Haase, A. T. (2011). Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections. J Clin Invest 121(3): 998-1008. (*Co-first author)
  9. Bosinger, S. E., Li, Q., Gordon, S. N., Klatt, N. R., Duan, L., Xu, L., Francella, N., Sidahmed, A., Smith, A. J., Cramer, E. M., Zeng, M., Masopust, D., Carlis, J. V., Ran, L., Vanderford, T. H., Paiardini, M., Isett, R. B., Baldwin, D. A., Else, J. G., Staprans, S. I., Silvestri, G., Haase, A. T. and Kelvin, D. J. (2009). Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. J Clin Invest 119(12): 3556-3572.
  10. Estes, J. D., Gordon, S. N., Zeng, M., Chahroudi, A. M., Dunham, R. M., Staprans, S. I., Reilly, C. S., Silvestri, G. and Haase, A. T. (2008). Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques. J Immunol 180(10): 6798-6807.
Protocols by Ming Zeng
  1. Ex vivo Co-culture of Lymphoid Tissue Stromal Cells and T Cells