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Jian-Guo He

Education

Ph.D. in Hydrobiology, State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-sen University, 1991

Current position

Professor in Marine Biology and Hydrobiology, School of Marine Sciences, Sun Yat-Sen University, Guangzhou, PR China

Publications (since 2007)

  1. Jia, K. T., Wu, Y. Y., Liu, Z. Y., Mi, S., Zheng, Y. W., He, J., Weng, S. P., Li, S. C., He, J. G.* and Guo, C. J.* (2013). Mandarin fish caveolin 1 interaction with major capsid protein of infectious spleen and kidney necrosis virus and its role in early stages of infection. J Virol 87(6): 3027-3038.
  2. Jia, K. T., Liu, Z. Y., Guo, C. J.*, Xia, Q., Mi, S., Li, X. D., Weng, S. P. and He, J. G. (2013). The potential role of microfilaments in host cells for infection with infectious spleen and kidney necrosis virus infection. Virol J 10: 77.
  3. Liu, Z. Y., Jia, K. T., Li, C., Weng, S. P., Guo, C. J.* and He, J. G.* (2013). A truncated Danio rerio PKZ isoform functionally interacts with eIF2α and inhibits protein synthesis. Gene 527(1): 292-300.
  4. Li, C., Weng, S., Chen, Y., Yu, X., Lu, L., Zhang, H., He, J. and Xu, X. (2012). Analysis of Litopenaeus vannamei transcriptome using the next-generation DNA sequencing technique. PLoS One 7(10): e47442.
  5. Dong, C., Li, X., Weng, S., Xie, S. and He, J. (2013). Emergence of fatal European genotype CyHV-3/KHV in mainland China. Vet Microbiol 162(1): 239-244.
  6. Dong, C., Xiong, X., Luo, Y., Weng, S., Wang, Q. and He, J. (2013). Efficacy of a formalin-killed cell vaccine against infectious spleen and kidney necrosis virus (ISKNV) and immunoproteomic analysis of its major immunogenic proteins. Vet Microbiol 162(2-4): 419-428.
  7. Shuang, F., Luo, Y., Xiong, X. P., Weng, S., Li, Y., He, J. and Dong, C. (2013). Virions proteins of an RSIV-type megalocytivirus from spotted knifejaw Oplegnathus punctatus (SKIV-ZJ07). Virology 437(2): 89-99.
  8. Li, C., Chen, Y., Weng, S., Li, S., Zuo, H., Yu, X., Li, H., He, J. and Xu, X. (2013). Presence of Tube isoforms in Litopenaeus vannamei suggests various regulatory patterns of signal transduction in invertebrate NF-κB pathway. Dev Comp Immunol.
  9. Guo, C. J., Wu, Y. Y., Yang, L. S., Yang, X. B., He, J., Mi, S., Jia, K. T., Weng, S. P., Yu, X. Q. and He, J. G. (2012). Infectious spleen and kidney necrosis virus (a fish iridovirus) enters Mandarin fish fry cells via caveola-dependent endocytosis. J Virol 86(5): 2621-2631.
  10. Guo, C. J., Yang, L. S., Zhang, Y. F., Wu, Y. Y., Weng, S. P., Yu, X. Q. and He, J. G. (2012). A novel viral SOCS from infectious spleen and kidney necrosis virus: interacts with Jak1 and inhibits IFN-αinduced Stat1/3 activation. PLoS One 7(7): e41092.
  11. Guo, C. J., Yang, X. B., Wu, Y. Y., Yang, L. S., Mi, S., Liu, Z. Y., Jia, K. T., Huang, Y. X., Weng, S. P., Yu, X. Q. and He, J. G. (2011). Involvement of caveolin-1 in the Jak-Stat signaling pathway and infectious spleen and kidney necrosis virus infection in mandarin fish (Siniperca chuatsi). Mol Immunol 48(8): 992-1000.
  12. Guo, C. J., Chen, W. J., Yuan, L. Q., Yang, L. S., Weng, S. P., Yu, X. Q. and He, J. G. (2011). The viral ankyrin repeat protein (ORF124L) from infectious spleen and kidney necrosis virus attenuates nuclear factor-κB activation and interacts with IκB kinase β. J Gen Virol 92(Pt 7): 1561-1570.
  13. Guo, C. J., Liu, D., Wu, Y. Y., Yang, X. B., Yang, L. S., Mi, S., Huang, Y. X., Luo, Y. W., Jia, K. T., Liu, Z. Y., Chen, W. J., Weng, S. P., Yu, X. Q. and He, J. G. (2011). Entry of tiger frog virus (an Iridovirus) into HepG2 cells via a pH-dependent, atypical, caveola-mediated endocytosis pathway. J Virol 85(13): 6416-6426.
  14. Chen, W. J., Guo, C. J., Zhou, Z. C., Yuan, L. Q., Xiang, Z. M., Weng, S. P., Zhang, Y. F., Yu, X. Q. and He, J. G. (2011). Molecular cloning of IKKβ from the mandarin fish Siniperca chuatsi and its up-regulation in cells by ISKNV infection. Vet Immunol Immunopathol 139(1): 61-66.
  15. Wang, L., Zhou, Z. C., Guo, C. J., Rao, X. Y., Xiao, J., Weng, S. P., Yin, Z. X., Yu, X. Q. and He, J. G. (2009). The α inhibitor of NF-κB (IκBα) from the mandarin fish binds with p65 NF-κB. Fish Shellfish Immunol 26(3): 473-482..
  16. Guo, C. J., Zhang, Y. F., Yang, L. S., Yang, X. B., Wu, Y. Y., Liu, D., Chen, W. J., Weng, S. P., Yu, X. Q. and He, J. G. (2009). The JAK and STAT family members of the mandarin fish Siniperca chuatsi: molecular cloning, tissues distribution and immunobiological activity. Fish Shellfish Immunol 27(2): 349-359.
  17. Li, C., Chen, Y. X., Zhang, S., Lu, L., Chen, Y. H., Chai, J., Weng, S., Chen, Y. G., He, J. and Xu, X. (2012). Identification, characterization, and function analysis of the Cactus gene from Litopenaeus vannamei. PLoS One 7(11): e49711.
  18. Xu, X., Weng, S., Lin, T., Tang, J., Huang, L., Wang, J., Yu, X., Lu, L., Huang, Z. and He, J. (2010). VP23R of infectious spleen and kidney necrosis virus mediates formation of virus-mock basement membrane to provide attaching sites for lymphatic endothelial cells. J Virol 84(22): 11866-11875.
  19. Xiang, Z., Dong, C., Qi, L., Chen, W., Huang, L., Li, Z., Xia, Q., Liu, D., Huang, M., Weng, S. and He, J. (2010). Characteristics of the interferon regulatory factor pairs zfIRF5/7 and their stimulation expression by ISKNV Infection in zebrafish (Danio rerio). Dev Comp Immunol 34(12): 1263-1273.
  20. Dong, C., Weng, S., Shi, X., Xu, X., Shi, N. and He, J. (2008).Development of a mandarin fish Siniperca chuatsi fry cell line suitable for the study of infectious spleen and kidney necrosis virus (ISKNV). Virus Res 135(2): 273-281.
  21. Xu, X., Zhang, L., Weng, S., Huang, Z., Lu, J., Lan, D., Zhong, X., Yu, X., Xu, A. and He, J. (2008). A zebrafish (Danio rerio) model of infectious spleen and kidney necrosis virus (ISKNV) infection. Virology 376(1): 1-12.
  22. Yang, L. S., Yin, Z. X., Liao, J. X., Huang, X. D., Guo, C. J., Weng, S. P., Chan, S. M., Yu, X. Q. and He, J. G. (2007). A Toll receptor in shrimp. Mol Immunol 44(8): 1999-2008.
Protocols by Jian-Guo He
  1. Virus Overlay Assay (Far-Western blotting)