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Yan Zhang


Ph.D., School of Dentistry, Hiroshima University, Japan, 2000

Current position

Group Leader, Professor, Cancer and Stem Cell Biology, School of Life Sciences, Sun Yat-sen University, Guangzhou Higher Education Mega Center, P. R. China; Sun Yat-sen University-Griffith University Joint Laboratory for Drug Discovery

Director, Biomedical Center, Institute of Dongguan Sun Yat-sen University, P. R. China

Selected Publications (since 2011)

  1. Zhang, H., Wu, H., Zheng, J., Yu, P., Xu, L., Jiang, P., Gao, J., Wang, H. and Zhang, Y.* (2013). Transforming growth factor beta1 signal is crucial for dedifferentiation of cancer cells to cancer stem cells in osteosarcoma. Stem Cells 31(3): 433-446.
  2. Yang, T., Fang, S., Zhang, H. X., Xu, L. X., Zhang, Z. Q., Yuan, K. T., Xue, C. L., Yu, H. L., Zhang, S., Li, Y. F., Shi, H. P. and Zhang, Y.* (2013). N-3 PUFAs have antiproliferative and apoptotic effects on human colorectal cancer stem-like cells in vitro. J Nutr Biochem 24(5): 744-753.
  3. Shi, X., Zhang, Y., Zheng, J. and Pan, J.* (2012). Reactive oxygen species in cancer stem cells. Antioxid Redox Signal 16(11): 1215-1228.
  4. Zeng, T., Gao, H., Yu, P., He, H., Ouyang, X., Deng, L. and Zhang, Y.* (2011). Up-regulation of kin17 is essential for proliferation of breast cancer. PLoS One 6(9): e25343.
  5. Zhu, Y., Yu, F., Jiao, Y., Feng, J., Tang, W., Yao, H., Gong, C., Chen, J., Su, F., Zhang, Y.* and Song, E. (2011). Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5. Clin Cancer Res 17(22): 7105-7115.
  6. Sun, D., Wang, X., Zhang, H., Deng, L. and Zhang, Y.* (2011). MMP9 mediates MICA shedding in human osteosarcomas. Cell Biol Int 35(6): 569-574.
    *Coresponding author

Book Chapter

  1. Zheng, J. and Zhang.Y. (2012). The microenvironment of cancer stem cell. Nutrition for Cancer. Beijing: People's Medical Publishing House. August, Chaper 5.
Protocols by Yan Zhang
  1. Chemosensitivity Assay