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Georgios   Nikolaidis

Georgios Nikolaidis


Ph.D. in Molecular Oncology, Department of Molecular & Clinical Cancer Medicine, University of Liverpool, 2012

Current position

Research Associate, University of Crete Medical School, Heraklion, Greece


  1. Shaw, R. J., Hobkirk, A. J., Nikolaidis, G., Woolgar, J. A., Triantafyllou, A., Brown, J. S., Liloglou, T. and Risk, J. M. (2013). Molecular Staging of Surgical Margins in Oral Squamous Cell Carcinoma Using Promoter Methylation of p16(INK4A), Cytoglobin, E-cadherin, and TMEFF2. Ann Surg Oncol 20(8): 2796-2802.
  2. Gkirtzimanaki, K., Gkouskou, K. K., Oleksiewicz, U., Nikolaidis, G., Vyrla, D., Liontos, M., Pelekanou, V., Kanellis, D. C., Evangelou, K., Stathopoulos, E. N., Field, J. K., Tsichlis, P. N., Gorgoulis, V., Liloglou, T. and Eliopoulos, A. G. (2013). TPL2 kinase is a suppressor of lung carcinogenesis. Proc Natl Acad Sci U S A 110(16): E1470-1479.
  3. Nikolaidis, G., Raji, O. Y., Markopoulou, S., Gosney, J. R., Bryan, J., Warburton, C., Walshaw, M., Sheard, J., Field, J. K. and Liloglou, T. (2012). DNA methylation biomarkers offer improved diagnostic efficiency in lung cancer. Cancer Res 72(22): 5692-5701.
  4. Gray, S. G., Baird, A. M., O'Kelly, F., Nikolaidis, G., Almgren, M., Meunier, A., Dockry, E., Hollywood, D., Ekstrom, T. J., Perry, A. S. and O'Byrne, K. J. (2012). Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor. Int J Mol Med 30(6): 1505-1511.
  5. Markopoulou, S., Nikolaidis, G. and Liloglou, T. (2012). DNA methylation biomarkers in biological fluids for early detection of respiratory tract cancer. Clin Chem Lab Med 50(10): 1723-1731.
  6. Daskalos, A., Oleksiewicz, U., Filia, A., Nikolaidis, G., Xinarianos, G., Gosney, J. R., Malliri, A., Field, J. K. and Liloglou, T. (2011). UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer. Cancer 117(5): 1027-1037.
  7. Schache, A. G., Hall, G., Woolgar, J. A., Nikolaidis, G., Triantafyllou, A., Lowe, D., Risk, J. M., Shaw, R. J. and Liloglou, T. (2010). Quantitative promoter methylation differentiates carcinoma ex pleomorphic adenoma from pleomorphic salivary adenoma. Br J Cancer 103(12): 1846-1851.
  8. Knight, L. J., Burrage, J., Bujac, S. R., Haggerty, C., Graham, A., Gibson, N. J., Ellison, G., Growcott, J. W., Brooks, A. N., Hughes, A. M., Xinarianos, G., Nikolaidis, G., Field, J. K. and Liloglou, T. (2009). Epigenetic silencing of the endothelin-B receptor gene in non-small cell lung cancer. Int J Oncol 34(2): 465-471.
  9. Daskalos, A., Nikolaidis, G., Xinarianos, G., Savvari, P., Cassidy, A., Zakopoulou, R., Kotsinas, A., Gorgoulis, V., Field, J. K. and Liloglou, T. (2009). Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer. Int J Cancer 124(1): 81-87.
  10. Pateras, I. S., Apostolopoulou, K., Koutsami, M., Evangelou, K., Tsantoulis, P., Liloglou, T., Nikolaidis, G., Sigala, F., Kittas, C., Field, J. K., Kotsinas, A. and Gorgoulis, V. G. (2006). Downregulation of the KIP family members p27(KIP1) and p57(KIP2) by SKP2 and the role of methylation in p57(KIP2) inactivation in nonsmall cell lung cancer. Int J Cancer 119(11): 2546-2556.
  11. Xinarianos, G., McRonald, F. E., Risk, J. M., Bowers, N. L., Nikolaidis, G., Field, J. K. and Liloglou, T. (2006). Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer. Hum Mol Genet 15(13): 2038-2044.
Protocols by Georgios Nikolaidis
  1. Quantitative Methylation Specific PCR (qMSP)