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Marcel Vergés


Ph.D. in Cell Biology, University of Barcelona, 1994

Current position

Tenure-track Lecturer, Medical Sciences Deparment, School of Medicine, University of Girona

Senior Researcher, Cardiovascular Genetics Center, Girona Biomedical Research Institute, Spain


  1. Riuro, H., Beltran-Alvarez, P., Tarradas, A., Selga, E., Campuzano, O., Verges, M., Pagans, S., Iglesias, A., Brugada, J., Brugada, P., Vazquez, F. M., Perez, G. J., Scornik, F. S. and Brugada, R. (2013). A missense mutation in the sodium channel beta2 subunit reveals SCN2B as a new candidate gene for Brugada syndrome. Hum Mutat 34(7): 961-966.
  2. Cuartero, Y., Mellado, M., Capell, A., Alvarez-Dolado, M. and Verges, M. (2012). Retromer regulates postendocytic sorting of beta-secretase in polarized Madin-Darby canine kidney cells. Traffic 13(10): 1393-1410.
  3. Su, T., Bryant, D. M., Luton, F., Verges, M., Ulrich, S. M., Hansen, K. C., Datta, A., Eastburn, D. J., Burlingame, A. L., Shokat, K. M. and Mostov, K. E. (2010). A kinase cascade leading to Rab11-FIP5 controls transcytosis of the polymeric immunoglobulin receptor. Nat Cell Biol 12(12): 1143-1153.
  4. Fuster, J. J., Gonzalez, J. M., Edo, M. D., Viana, R., Boya, P., Cervera, J., Verges, M., Rivera, J. and Andres, V. (2010). Tumor suppressor p27(Kip1) undergoes endolysosomal degradation through its interaction with sorting nexin 6. FASEB J 24(8): 2998-3009.
  5. Verges, M. (2008). Retromer: multipurpose sorting and specialization in polarized transport. Int Rev Cell Mol Biol 271: 153-198. (Review/Book Chapter)
  6. Verges, M. (2007). Retromer and sorting nexins in development. Front Biosci 12: 3825-3851.
  7. Verges, M., Sebastian, I. and Mostov, K. E. (2007). Phosphoinositide 3-kinase regulates the role of retromer in transcytosis of the polymeric immunoglobulin receptor. Exp Cell Res 313(4): 707-718. (corresponding author: M. Vergés)
  8. Mostov, K., Brakeman, P., Datta, A., Gassama, A., Katz, L., Kim, M., Leroy, P., Levin, M., Liu, K., Martin, F., O'Brien, L. E., Verges, M., Su, T., Tang, K., Tanimizu, N., Yamaji, T. and Yu, W. (2005). Formation of multicellular epithelial structures. Novartis Found Symp 269: 193-200; discussion 200-195, 223-130. (Book Chapter)
  9. Verges, M., Luton, F., Gruber, C., Tiemann, F., Reinders, L. G., Huang, L., Burlingame, A. L., Haft, C. R. and Mostov, K. E. (2004). The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor. Nat Cell Biol 6(8): 763-769.
  10. Verges, M., Bensadoun, A., Herz, J., Belcher, J. D. and Havel, R. J. (2004). Endocytosis of hepatic lipase and lipoprotein lipase into rat liver hepatocytes in vivo is mediated by the low density lipoprotein receptor-related protein. J Biol Chem 279(10): 9030-9036.
  11. Mostov, K. E., Verges, M. and Altschuler, Y. (2000). Membrane traffic in polarized epithelial cells. Curr Opin Cell Biol 12(4): 483-490.
  12. Luton, F., Verges, M., Vaerman, J. P., Sudol, M. and Mostov, K. E. (1999). The SRC family protein tyrosine kinase p62yes controls polymeric IgA transcytosis in vivo. Mol Cell 4(4): 627-632. (The two first authors contributed equally to this work)
  13. Verges, M., Havel, R. J. and Mostov, K. E. (1999). A tubular endosomal fraction from rat liver: biochemical evidence of receptor sorting by default. Proc Natl Acad Sci U S A 96(18): 10146-10151.
  14. Bergeron, N., Kotite, L., Verges, M., Blanche, P., Hamilton, R. L., Krauss, R. M., Bensadoun, A. and Havel, R. J. (1998). Lamellar lipoproteins uniquely contribute to hyperlipidemia in mice doubly deficient in apolipoprotein E and hepatic lipase. Proc Natl Acad Sci U S A 95(26): 15647-15652.
  15. Verges, M., Castro, A., Jaumot, M., Bachs, O. and Enrich, C. (1997). Cyclin A is present in the endocytic compartment of rat liver cells and increases during liver regeneration. Biochem Biophys Res Commun 230(1): 49-53.
  16. Enrich, C., Verges, M. and Evans, W. H. (1995). Functional identification of three major phosphoproteins in endocytic fractions from rat liver. A comparative in vivo and in vitro study. Eur J Biochem 231(3): 802-808.
  17. Castro, A., Jaumot, M., Verges, M., Agell, N. and Bachs, O. (1994). Microsomal localization of cyclin A and cdk2 in proliferating rat liver cells. Biochem Biophys Res Commun 201(3): 1072-1078.
  18. Enrich, C., Verges, M. and Evans, W. H. (1992). Reorganization of the endocytic compartment in regenerating liver. Exp Cell Res 201(2): 399-407.
  19. Enrich, C., Verges, M. and Evans, W. H. (1992). Differential expression of asialoglycoprotein receptor subunits in the endocytic compartment during liver regeneration. J Cell Physiol 150(2): 344-352.

Protocols by Marcel Vergés
  1. Cell Surface Protein Biotinylation and Analysis