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Gabriella Castoria

Education

M.D., University Federico II- Naples, 1981

Current position

Full Professor of General Pathology at Department of Biochemistry, Biophysics and General Pathology - Second University of Naples

Publications (since 2005)

Peer reviewed journals

  1. Tesei, A., Leonetti, C., Di Donato, M., Gabucci, E., Porru, M., Varchi, G., Guerrini, A., Amadori, D., Arienti, C., Pignatta, S., Paganelli, G., Caraglia, M., Castoria, G. and Zoli, W. (2013). Effect of small molecules modulating androgen receptor (SARMs) in human prostate cancer models. PLoS One 8(5): e62657
  2. Varchi, G., Guerrini, A., Tesei, A., Brigliadori, G., Bertucci, C., Di Donato, M. and Castoria, G. (2012). Nonsteroidal Androgen Receptor Ligands: Versatile Syntheses and Biological Data. ACS Medicinal Chemistry Letters 3(6): 454-458.
  3. Giovannelli, P., Di Donato, M., Giraldi, T., Migliaccio, A., Castoria, G. and Auricchio, F. (2012). Targeting rapid action of sex-steroid receptors in breast and prostate cancers. Front Biosci (Elite Ed) 4: 453-461.
  4. Castoria, G., Giovannelli, P., Lombardi, M., De Rosa, C., Giraldi, T., de Falco, A., Barone, M. V., Abbondanza, C., Migliaccio, A. and Auricchio, F. (2012). Tyrosine phosphorylation of estradiol receptor by Src regulates its hormone-dependent nuclear export and cell cycle progression in breast cancer cells. Oncogene 31(46): 4868-4877.
  5. Migliaccio, A., Castoria, G., de Falco, A., Bilancio, A., Giovannelli, P., Di Donato, M., Marino, I., Yamaguchi, H., Appella, E. and Auricchio, F. (2012). Polyproline and Tat transduction peptides in the study of the rapid actions of steroid receptors. Steroids 77(10): 974-978.
  6. Migliaccio, A., Castoria, G. and Auricchio, F. (2011). Analysis of androgen receptor rapid actions in cellular signaling pathways: receptor/Src association. Methods Mol Biol 776: 361-370.
  7. Giovannelli, P., Di Donato, M., Giraldi, T., Migliaccio, A., Castoria, G. and Auricchio, F. (2011). Targeting rapid action of sex steroid receptors in breast and prostate cancers. Front Biosci 16: 2224-2232.
  8. Castoria, G., D'Amato, L., Ciociola, A., Giovannelli, P., Giraldi, T., Sepe, L., Paolella, G., Barone, M. V., Migliaccio, A. and Auricchio, F. (2011). Androgen-induced cell migration: role of androgen receptor/filamin A association. PLoS One 6(2): e17218.
  9. Giraldi, T., Giovannelli, P., Di Donato, M., Castoria, G., Migliaccio, A. and Auricchio, F. (2010). Steroid signaling activation and intracellular localization of sex steroid receptors. J Cell Commun Signal 4(4): 161-172.
  10. Migliaccio, A., Castoria, G., Giovannelli, P. and Auricchio, F. (2010). Cross talk between epidermal growth factor (EGF) receptor and extra nuclear steroid receptors in cell lines. Mol Cell Endocrinol 327(1-2): 19-24
  11. Castoria, G., Migliaccio, A., Giovannelli, P. and Auricchio, F. (2010). Cell proliferation regulated by estradiol receptor: Therapeutic implications. Steroids 75(8-9): 524-52.
  12. Genua, M., Pandini, G., Sisci, D., Castoria, G., Maggiolini, M., Vigneri, R. and Belfiore, A. (2009). Role of cyclic AMP response element-binding protein in insulin-like growth factor-i receptor up-regulation by sex steroids in prostate cancer cells. Cancer Res 69(18): 7270-7277.
  13. Castoria, G., Migliaccio, A. and Auricchio, F. (2009). Signaling-dependent nuclear export of estradiol receptor controls cell cycle progression in breast cancer cells. Mol Cell Endocrinol 308(1-2): 26-31.
  14. Lombardi, M., Castoria, G., Migliaccio, A., Barone, M. V., Di Stasio, R., Ciociola, A., Bottero, D., Yamaguchi, H., Appella, E. and Auricchio, F. (2008). Hormone-dependent nuclear export of estradiol receptor and DNA synthesis in breast cancer cells. J Cell Biol 182(2): 327-340.
  15. Auricchio, F., Migliaccio, A. and Castoria, G. (2008). Sex-steroid hormones and EGF signalling in breast and prostate cancer cells: targeting the association of Src with steroid receptors. Steroids 73(9-10): 880-884.
  16. Castoria, G., Migliaccio, A., D'Amato, L., Di Stasio, R., Ciociola, A., Lombardi, M., Bilancio, A., Di Domenico, M., de Falco, A. and Auricchio, F. (2008). Integrating signals between cAMP and MAPK pathways in breast cancer. Front Biosci 13: 1318-1327.
  17. Varricchio, L., Migliaccio, A., Castoria, G., Yamaguchi, H., de Falco, A., Di Domenico, M., Giovannelli, P., Farrar, W., Appella, E. and Auricchio, F. (2007). Inhibition of estradiol receptor/Src association and cell growth by an estradiol receptor alpha tyrosine-phosphorylated peptide. Mol Cancer Res 5(11): 1213-1221.
  18. Migliaccio, A., Varricchio, L., De Falco, A., Castoria, G., Arra, C., Yamaguchi, H., Ciociola, A., Lombardi, M., Di Stasio, R., Barbieri, A., Baldi, A., Barone, M. V., Appella, E. and Auricchio, F. (2007). Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth. Oncogene 26(46): 6619-6629.
  19. Migliaccio, A., Castoria, G. and Auricchio, F. (2007). Src-dependent signalling pathway regulation by sex-steroid hormones: therapeutic implications. Int J Biochem Cell Biol 39(7-8): 1343-1348.
  20. Barone, M. V., Gimigliano, A., Castoria, G., Paolella, G., Maurano, F., Paparo, F., Maglio, M., Mineo, A., Miele, E., Nanayakkara, M., Troncone, R. and Auricchio, S. (2007). Growth factor-like activity of gliadin, an alimentary protein: implications for coeliac disease. Gut 56(4): 480-488.
  21. Migliaccio, A., Castoria, G., Di Domenico, M., Ciociola, A., Lombardi, M., De Falco, A., Nanayakkara, M., Bottero, D., De Stasio, R., Varricchio, L. and Auricchio, F. (2006). Crosstalk between EGFR and extranuclear steroid receptors. Ann N Y Acad Sci 1089: 194-200.
  22. Migliaccio, A., Castoria, G., Di Domenico, M., Ballare, C., Beato, M. and Auricchio, F. (2005). The progesterone receptor/estradiol receptor association and the progestin-triggered S-phase entry. Ernst Schering Res Found Workshop(52): 39-54.
  23. Migliaccio, A., Di Domenico, M., Castoria, G., Nanayakkara, M., Lombardi, M., de Falco, A., Bilancio, A., Varricchio, L., Ciociola, A. and Auricchio, F. (2005). Steroid receptor regulation of epidermal growth factor signaling through Src in breast and prostate cancer cells: steroid antagonist action. Cancer Res 65(22): 10585-10593.

Books

  1. *Castoria, G. and Migliaccio, A. (2012). Advances in rapid sex-steroid action: new challenges and new chances in breast and prostate cancers, Springer.
    *Co-Editor of the book
Protocols by Gabriella Castoria
  1. Estradiol Receptor (ER) Chromatin Immunoprecipitation in MCF-7 Cells