Education

Ph.D, Duke University, USA, 1999

Current position

Professor, Beijing Institute for Brain Disorders, Capital Medical University, China

Publications

1. Wang, Y. L. and Zhang, C. X. (2017). Putting a brake on synaptic vesicle endocytosis. Cell Mol Life Sci 74(16): 2917-2927. 

2. Du, C., Wang, Y., Zhang, F., Yan, S., Guan, Y., Gong, X., Zhang, T., Cui, X., Wang, X. and Zhang, C. X. (2017). Synaptotagmin-11 inhibits cytokine secretion and phagocytosis in microglia. Glia 65(10): 1656-1667. 

3. Wang, C., Wang, Y., Hu, M., Chai, Z., Wu, Q., Huang, R., Han, W., Zhang, C. X. and Zhou, Z. (2016). Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. EMBO Rep 17(1): 47-63.

4. Kuo, S. T., Wu, Q. H., Liu, B., Xie, Z. L., Wu, X., Shang, S. J., Zhang, X. Y., Kang, X. J., Liu, L. N., Zhu, F. P., Wang, Y. S., Hu, M. Q., Xu, H. D., Zhou, L., Liu, B., Chai, Z. Y., Zhang, Q. F., Liu, W., Teng, S. S., Wang, C. H., Guo, N., Dou, H. Q., Zuo, P. L., Zheng, L. H., Zhang, C. X., Zhu, D. S., Wang, L., Wang, S. R. and Zhou, Z. (2014). Importing, caring, breeding, genotyping, and phenotyping a genetic mouse in a Chinese university. J Mol Neurosci 53(3): 487-492. 

5. Zuo, P. L., Yao, W., Sun, L., Kuo, S. T., Li, Q., Wang, S. R., Dou, H. Q., Xu, H. D., Zhang, C. X., Kang, X. J., Zhou, Z. and Zhang, B. (2013). Impulse-dependent extracellular resting dopamine concentration in rat striatum in vivo. Neurochem Int 62(1): 50-57. 

6. Zhang, B., Zhang, X. Y., Luo, P. F., Huang, W., Zhu, F. P., Liu, T., Du, Y. R., Wu, Q. H., Lu, J., Xiu, Y., Liu, L. N., Huang, H. P., Guo, S., Zheng, H., Zhang, C. X. and Zhou, Z. (2012). Action potential-triggered somatic exocytosis in mesencephalic trigeminal nucleus neurons in rat brain slices. J Physiol 590(4): 753-762. 

7. Huang, H. P., Zhu, F. P., Chen, X. W., Xu, Z. Q., Zhang, C. X. and Zhou, Z. (2012). Physiology of quantal norepinephrine release from somatodendritic sites of neurons in locus coeruleus. Front Mol Neurosci 5: 29. 

8. Zhang, B., Sun, L., Yang, Y. M., Huang, H. P., Zhu, F. P., Wang, L., Zhang, X. Y., Guo, S., Zuo, P. L., Zhang, C. X., Ding, J. P., Wang, L. Y. and Zhou, Z. (2011). Action potential bursts enhance transmitter release at a giant central synapse. J Physiol 589(Pt 9): 2213-2227. 

9. Xiong, W., Liu, T., Wang, Y., Chen, X., Sun, L., Guo, N., Zheng, H., Zheng, L., Ruat, M., Han, W., Zhang, C. X. and Zhou, Z. (2011). An inhibitory effect of extracellular Ca2+ on Ca2+-dependent exocytosis. PLoS One 6(10): e24573.

10. Wang, S. R., Yao, W., Huang, H. P., Zhang, B., Zuo, P. L., Sun, L., Dou, H. Q., Li, Q., Kang, X. J., Xu, H. D., Hu, M. Q., Jin, M., Zhang, L., Mu, Y., Peng, J. Y., Zhang, C. X., Ding, J. P., Li, B. M. and Zhou, Z. (2011). Role of vesicle pools in action potential pattern-dependent dopamine overflow in rat striatum in vivo. J Neurochem 119(2): 342-353. 

11. Liu, T., Sun, L., Xiong, Y., Shang, S., Guo, N., Teng, S., Wang, Y., Liu, B., Wang, C., Wang, L., Zheng, L., Zhang, C. X., Han, W. and Zhou, Z. (2011). Calcium triggers exocytosis from two types of organelles in a single astrocyte. J Neurosci 31(29): 10593-10601. 

12. Liu, T., Shang, S. J., Liu, B., Wang, C. H., Wang, Y. S., Xiong, W., Zheng, L. H., Zhang, C. X. and Zhou, Z. (2011). Two distinct vesicle pools for depolarization-induced exocytosis in somata of dorsal root ganglion neurons. J Physiol 589(Pt 14): 3507-3515. 

13. Zheng, H., Fan, J., Xiong, W., Zhang, C., Wang, X. B., Liu, T., Liu, H. J., Sun, L., Wang, Y. S., Zheng, L. H., Wang, B. R., Zhang, C. X. and Zhou, Z. (2009). Action potential modulates Ca2+-dependent and Ca2+-independent secretion in a sensory neuron. Biophys J 96(6): 2449-2456. 

14. Chen, X.-W., Mu, Y., Huang, H.-P., Guo, N., Zhang, B., Fan, S.-Y., Xiong, J.-X., Wang, S.-R., Xiong, W., Huang, W., Liu, T., Zheng, L.-H., Zhang, C. X., Li, L.-H., Yu, Z.-P., Hu, Z.-A. and Zhou, Z. (2008). Hypocretin-1 Potentiates NMDA Receptor-Mediated Somatodendritic Secretion from Locus Ceruleus Neurons. The Journal of Neuroscience 28(12): 3202-3208. 

15. Chen, X. W., Huang, W., Yan, J. A., Fan, H. X., Guo, N., Lu, J., Xiu, Y., Gu, J. L., Zhang, C. X., Ruan, H. Z., Hu, Z. A., Yu, Z. P. and Zhou, Z. (2008). Reinvestigation of the effect of orexin A on catecholamine release from adrenal chromaffin cells. Neurosci Lett 436(2): 181-184. 

16. Chen, X. W., Feng, Y. Q., Hao, C. J., Guo, X. L., He, X., Zhou, Z. Y., Guo, N., Huang, H. P., Xiong, W., Zheng, H., Zuo, P. L., Zhang, C. X., Li, W. and Zhou, Z. (2008). DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release. J Cell Biol 181(5): 791-801. 

17. Zhang, C. X. and Hsieh, T. S. (2007). Preparation of membrane proteins from Drosophila embryos. CSH Protoc 2007: pdb.prot4711. 

18. Yu, X., Chen, X. W., Zhou, P., Yao, L., Liu, T., Zhang, B., Li, Y., Zheng, H., Zheng, L. H., Zhang, C. X., Bruce, I., Ge, J. B., Wang, S. Q., Hu, Z. A., Yu, H. G. and Zhou, Z. (2007). Calcium influx through If channels in rat ventricular myocytes. Am J Physiol Cell Physiol 292(3): C1147-1155. 

19. Le Clainche, C., Pauly, B. S., Zhang, C. X., Engqvist-Goldstein, A. E., Cunningham, K. and Drubin, D. G. (2007). A Hip1R-cortactin complex negatively regulates actin assembly associated with endocytosis. Embo j 26(5): 1199-1210. 

20. Bradley, S. V., Hyun, T. S., Oravecz-Wilson, K. I., Li, L., Waldorff, E. I., Ermilov, A. N., Goldstein, S. A., Zhang, C. X., Drubin, D. G., Varela, K., Parlow, A., Dlugosz, A. A. and Ross, T. S. (2007). Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1. Hum Mol Genet 16(11): 1279-1292. 

21. Zhang, C. X., Engqvist-Goldstein, A. E., Carreno, S., Owen, D. J., Smythe, E. and Drubin, D. G. (2005). Multiple roles for cyclin G-associated kinase in clathrin-mediated sorting events. Traffic 6(12): 1103-1113. 

22. Engqvist-Goldstein, A. E., Zhang, C. X., Carreno, S., Barroso, C., Heuser, J. E. and Drubin, D. G. (2004). RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery. Mol Biol Cell 15(4): 1666-1679. 

23. Carreno, S., Engqvist-Goldstein, A. E., Zhang, C. X., McDonald, K. L. and Drubin, D. G. (2004). Actin dynamics coupled to clathrin-coated vesicle formation at the trans-Golgi network. J Cell Biol 165(6): 781-788. 

24. Zhang, C. X., Rothwell, W. F., Sullivan, W. and Hsieh, T. S. (2000). Discontinuous actin hexagon, a protein essential for cortical furrow formation in Drosophila, is membrane associated and hyperphosphorylated. Mol Biol Cell 11(3): 1011-1022. 

25. Zhang, C. X., Chen, A. D., Gettel, N. J. and Hsieh, T. S. (2000). Essential functions of DNA topoisomerase I in Drosophila melanogaster. Dev Biol 222(1): 27-40. 

26. Rothwell, W. F., Zhang, C. X., Zelano, C., Hsieh, T. S. and Sullivan, W. (1999). The Drosophila centrosomal protein Nuf is required for recruiting Dah, a membrane associated protein, to furrows in the early embryo. J Cell Sci 112 ( Pt 17): 2885-2893. 

27. Brown, S. D., Zhang, C. X., Chen, A. D. and Hsieh, T. S. (1998). Structure of the Drosophila DNA topoisomerase I gene and expression of messages with different lengths in the 3' untranslated region. Gene 211(2): 195-203. 

28. Zhang, C. X., Lee, M. P., Chen, A. D., Brown, S. D. and Hsieh, T. (1996). Isolation and characterization of a Drosophila gene essential for early embryonic development and formation of cortical cleavage furrows. The Journal of Cell Biology 134(4): 923-934.