Welcome guest, Login | Register


Julia M. Martinez Gomez


Ph.D. in Sciences, University of Zurich, 2008

Current position

Research Fellow, Immunology Programme, Department of Microbiology, National University of Singapore


  1. Martínez Gómez JM, Chen L, Schwarz H, Karrasch T (2013). CD137 facilitates the resolution of acute DSS-induced colonic inflammation in mice. Submitted for publication.
  2. Martínez Gómez JM, Koh HQV, Yan B, Lin WW, Ang LTM ,Zainul Rahim SZ, Schwarz H, Alonso S (2013). The CD137 ligand (CD137L) signaling pathway contributes to the adaptive immune responses to M. tuberculosis infection. Under review.
  3. Tang, Q., Jiang, D., Alonso, S., Pant, A., Martinez Gomez, J. M., Kemeny, D. M., Chen, L. and Schwarz, H. (2013). CD137 ligand signaling enhances myelopoiesis during infections. Eur J Immunol. [Epub ahead of print]
  4. Martinez Gomez, J. M., Croxford, J. L., Yeo, K. P., Angeli, V., Schwarz, H. and Gasser, S. (2012). Development of experimental autoimmune encephalomyelitis critically depends on CD137 ligand signaling. J Neurosci 32(50): 18246-18252.
  5. Yeo, Y. A., Martinez Gomez, J. M., Croxford, J. L., Gasser, S., Ling, E. A. and Schwarz, H. (2012). CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. J Neuroinflammation 9: 173.
  6. Lin, W., Mathys, V., Ang, E. L., Koh, V. H., Martinez Gomez, J. M., Ang, M. L., Zainul Rahim, S. Z., Tan, M. P., Pethe, K. and Alonso, S. (2012). Urease activity represents an alternative pathway for Mycobacterium tuberculosis nitrogen metabolism. Infect Immun 80(8): 2771-2779.
  7. Senti, G., Crameri, R., Kuster, D., Johansen, P., Martinez-Gomez, J. M., Graf, N., Steiner, M., Hothorn, L. A., Gronlund, H., Tivig, C., Zaleska, A., Soyer, O., van Hage, M., Akdis, C. A., Akdis, M., Rose, H. and Kundig, T. M. (2012). Intralymphatic immunotherapy for cat allergy induces tolerance after only 3 injections. J Allergy Clin Immunol 129(5): 1290-1296.
  8. Tang, Q., Jiang, D., Shao, Z., Martinez Gomez, J. M. and Schwarz, H. (2011). Species difference of CD137 ligand signaling in human and murine monocytes. PLoS One 6(1): e16129.
  9. Johansen, P., Mohanan, D., Martinez-Gomez, J. M., Kundig, T. M. and Gander, B. (2010). Lympho-geographical concepts in vaccine delivery. J Control Release 148(1): 56-62.
  10. Martinez-Gomez, J. M., Johansen, P., Erdmann, I., Senti, G., Crameri, R. and Kundig, T. M. (2009). Intralymphatic injections as a new administration route for allergen-specific immunotherapy. Int Arch Allergy Immunol 150(1): 59-65
  11. Martinez-Gomez, J. M., Johansen, P., Rose, H., Steiner, M., Senti, G., Rhyner, C., Crameri, R. and Kundig, T. M. (2009). Targeting the MHC class II pathway of antigen presentation enhances immunogenicity and safety of allergen immunotherapy. Allergy 64(1): 172-178
  12. Martinez Gomez, J. M., Csaba, N., Fischer, S., Sichelstiel, A., Kundig, T. M., Gander, B. and Johansen, P. (2008). Surface coating of PLGA microparticles with protamine enhances their immunological performance through facilitated phagocytosis. J Control Release 130(2): 161-167.
  13. Martinez Gomez, J. M., Fischer, S., Csaba, N., Kundig, T. M., Merkle, H. P., Gander, B. and Johansen, P. (2007). A protective allergy vaccine based on CpG- and protamine-containing PLGA microparticles. Pharm Res 24(10): 1927-1935.
  14. Johansen, P., Senti, G., Maria Martinez Gomez, J. and Kundig, T. M. (2008). Medication with antihistamines impairs allergen-specific immunotherapy in mice. Clin Exp Allergy 38(3): 512-519.
  15. Johansen, P., Martinez Gomez, J. M. and Gander, B. (2007). Development of synthetic biodegradable microparticulate vaccines: a roller coaster story. Expert Rev Vaccines 6(4): 471-474.
  16. 5. Senti, G., Martinez Gomez, J. M., Rettig, L., Wuthrich, B., Kundig, T. M. and Johansen, P. (2006). Immunotherapeutic targeting of allergic disease. Inflamm Allergy Drug Targets 5(4): 243-252.
  17. Johansen, P., Senti, G., Martinez Gomez, J. M., Storni, T., von Beust, B. R., Wuthrich, B., Bot, A. and Kundig, T. M. (2005). Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy. Clin Exp Allergy 35(12): 1591-1598.
  18. Johansen, P., Senti, G., Martinez Gomez, J. M., Wuthrich, B., Bot, A. and Kundig, T. M. (2005). Heat denaturation, a simple method to improve the immunotherapeutic potential of allergens. Eur J Immunol 35(12): 3591-3598.
  19. Senti, G., Johansen, P., Martinez Gomez, J., Prinz Varicka, B. M. and Kundig, T. M. (2005). Efficacy and safety of allergen-specific immunotherapy in rhinitis, rhinoconjunctivitis, and bee/wasp venom allergies. Int Rev Immunol 24(5-6): 519-531.
  20. Mohajeri, M. H., Gaugler, M. N., Martinez, J., Tracy, J., Li, H., Crameri, A., Kuehnle, K., Wollmer, M. A. and Nitsch, R. M. (2004). Assessment of the bioactivity of antibodies against beta-amyloid peptide in vitro and in vivo. Neurodegener Dis 1(4-5): 160-167.
Protocols by Julia M. Martinez Gomez
  1. Isolation of Infiltrating Leukocytes from the Spinal Cord of Mice