LB
Luke Bown
  • Ph.D Student, Memorial University of Newfoundland
Research fields
  • Microbiology
Personal information

Education

B. Sc. (Hons), Memorial University of Newfoundland, 2014

Research focus

Streptomyces, natural products

Publications

Bown, L. †, Srivastava, S.K. †, Piercey, B.M. †, McIsaac, C.K., Tahlan, K. (2017). Mycobacterial Membrane Proteins QcrB and AtpE: Roles in Energetics, Antibiotic Targets and Associated Mechanisms of Resistance. The Journal of Membrane Biology: 1-13. (†Co-first authors)

Bown, L. & Bignell, D.R.D. (2017). Draft Genome Sequence of the Plant Pathogen Streptomyces sp. 11-1-2. Genome Announcements 5(37): e00968-17.

Bown,L., Li, Y., Berrue, F., Verhoeven, J., Dufour, S. and Bignell, D. (2017). Biosynthesis and evolution of coronafacoyl phytotoxin production in the common scab pathogen Streptomyces scabies. Applied and Environmental Microbiology, AEM-01169.

Bown, L. & Bignell, D.R. (2017). Purification of N-coronafacoyl Phytotoxins from Streptomyces scabies. Bio-protocol 7(7): e2214. DOI: 10.21769/BioProtoc.2214.

Hynes, A., Shakya, M., Mercer, R., Grüll, M., Bown, L., Davidson, F., Steffen, E., Matchem, H., Peach, M., Berger, T., Grebe, K., Zhaxybayeva, O. & Lang, A. (2016). Functional and evolutionary characterization of a gene transfer agent’s multi-locus “genome”. Molecular Biology and Evolution, 33(10): 2530-2543.

Bown, L.†, Altowairish, M.†, Fyans, J.K. & Bignell, D.R.D. (2016). Production of the Streptomyces scabies coronafacoyl phytotoxins involves a novel biosynthetic pathway with an F420-dependent oxidoreductase and a short-chain dehydrogenase/reductase. Molecular Microbiology, 101(1): 122-135. (†Co-first authors)

Fyans, J.K.†, Bown, L.† & Bignell, D.R.D. (2016). Isolation and characterization of plant pathogenic Streptomyces species associated with common scab-infected potato tubers in Newfoundland. Phytopathology, 106(2): 123-131. (†Co-first authors)

Cheng, Z., Bown, L., Tahlan, K. & Bignell, D.R.D. (2015). Regulation of coronafacoyl phytotoxin production by the PAS-LuxR family regulator CfaR in the common scab pathogen Streptomyces scabies. Plos ONE, 10(3): e0122450.
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