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Roop   Mallik

Roop Mallik


Ph.D in Department of Condensed Matter Physics, Tata Institute of Fundamental Research, Mumbai, India

Current Position

Associate Professor, Department of Biological Sciences, Tata Institute of Fundamental Research
Senior Research Fellow, Department of Biotechnology Alliance, Wellcome Trust

Publications (selected)

  1. Pathak, D. and Mallik, R. (2016). Lipid - Motor Interactions: Soap Opera or Symphony? Curr Opin Cell Biol. [Epub ahead of print]
  2. Rai, A., Pathak, D., Thakur, S., Singh, S., Dubey, A. K. and Mallik, R. (2016). Dynein Clusters into Lipid Microdomains on Phagosomes to Drive Rapid Transport toward Lysosomes. Cell 164(4): 722-734.
  3. Chanduri, M., Rai, A., Malla, A. B., Wu, M., Fiedler, D., Mallik, R. and Bhandari, R. (2016). Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport. Biochem J 473(19): 3031-3047.
  4. Barak, P., Rai, A., Dubey, A. K., Rai, P. and Mallik, R. (2014). Reconstitution of microtubule-dependent organelle transport. Methods Enzymol 540: 231-248.
  5. Mallik, R., Rai, A. K., Barak, P., Rai, A. and Kunwar, A. (2013). Teamwork in microtubule motors. Trends Cell Biol 23(11): 575-582.
  6. Rai, A. K., Rai, A., Ramaiya, A. J., Jha, R. and Mallik, R. (2013). Molecular adaptations allow dynein to generate large collective forces inside cells. Cell 152(1-2): 172-182.
  7. Barak, P., Rai, A., Rai, P. and Mallik, R. (2013). Quantitative optical trapping on single organelles in cell extract. Nat Methods 10(1): 68-70.
Protocols by Roop Mallik
  1. Isolation of Latex Bead Phagosomes from Dictyostelium for in vitro Functional Assays