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Ritu   Chakravarti

Ritu Chakravarti


Ph.D in Biotechnology, Indian Institute of Technology Delhi, India

Current Position

Assistant Professor in the Department of Surgery at University of Toledo College of Medicine and Life Sciences


  1. Chakravarti, R., Gupta, K., Swain, M., Willard, B., Scholtz, J., Svensson, L. G., Roselli, E. E., Pettersson, G., Johnston, D. R., Soltesz, E. G., Yamashita, M., Stuehr, D., Daly, T. M. and Hoffman, G. S. (2015). 14-3-3 in Thoracic Aortic Aneurysms: Identification of a Novel Autoantigen in Large Vessel Vasculitis. Arthritis Rheumatol 67(7): 1913-1921.
  2. Chakravarti, R., Gupta, K., Majors, A., Ruple, L., Aronica, M. and Stuehr, D. J. (2015). Novel insights in mammalian catalase heme maturation: effect of NO and thioredoxin-1. Free Radic Biol Med 82: 105-113.
  3. Zhang, H., Amick, J., Chakravarti, R., Santarriaga, S., Schlanger, S., McGlone, C., Dare, M., Nix, J. C., Scaglione, K. M., Stuehr, D. J., Misra, S. and Page, R. C. (2015). A bipartite interaction between Hsp70 and CHIP regulates ubiquitination of chaperoned client proteins. Structure 23(3): 472-482.
  4. Revsbech, I. G., Shen, X., Chakravarti, R., Jensen, F. B., Thiel, B., Evans, A. L., Kindberg, J., Frobert, O., Stuehr, D. J., Kevil, C. G. and Fago, A. (2014). Hydrogen sulfide and nitric oxide metabolites in the blood of free-ranging brown bears and their potential roles in hibernation. Free Radic Biol Med 73: 349-357.
  5. Chakravarti, R. and Stuehr, D. J. (2012). Thioredoxin-1 regulates cellular heme insertion by controlling S-nitrosation of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem 287(20): 16179-16186.
  6. Hannibal, L., Collins, D., Brassard, J., Chakravarti, R., Vempati, R., Dorlet, P., Santolini, J., Dawson, J. H. and Stuehr, D. J. (2012). Heme binding properties of glyceraldehyde-3-phosphate dehydrogenase. Biochemistry 51(43): 8514-8529.
  7. Aytekin, M., Aulak, K. S., Haserodt, S., Chakravarti, R., Cody, J., Minai, O. A. and Dweik, R. A. (2012). Abnormal platelet aggregation in idiopathic pulmonary arterial hypertension: role of nitric oxide. Am J Physiol Lung Cell Mol Physiol 302(6): L512-520.
  8. Chakravarti, R., Aulak, K. S., Fox, P. L. and Stuehr, D. J. (2010). GAPDH regulates cellular heme insertion into inducible nitric oxide synthase. Proc Natl Acad Sci U S A 107(42): 18004-18009.
  9. Waheed, S. M., Ghosh, A., Chakravarti, R., Biswas, A., Haque, M. M., Panda, K. and Stuehr, D. J. (2010). Nitric oxide blocks cellular heme insertion into a broad range of heme proteins. Free Radic Biol Med 48(11): 1548-1558.
  10. Valiyaveettil, M., Bentley, A. A., Gursahaney, P., Hussien, R., Chakravarti, R., Kureishy, N., Prag, S. and Adams, J. C. (2008). Novel role of the muskelin-RanBP9 complex as a nucleocytoplasmic mediator of cell morphology regulation. J Cell Biol 182(4): 727-739.
  11. Chakravarti, R. and Adams, J. C. (2006). Comparative genomics of the syndecans defines an ancestral genomic context associated with matrilins in vertebrates. BMC Genomics 7: 83.
  12. Chakravarti, R., Sapountzi, V. and Adams, J. C. (2005). Functional role of syndecan-1 cytoplasmic V region in lamellipodial spreading, actin bundling, and cell migration. Mol Biol Cell 16(8): 3678-3691.
Protocols by Ritu Chakravarti
  1. Biochemical Analysis of Caspase-8-dependent Proteolysis of IRF3 in Virus-infected Cells
  2. Qualitative and Quantitative Assay for Detection of Circulating Autoantibodies against Human Aortic Antigen