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Jennifer L. Larson-Casey

Jennifer L. Larson-Casey


Ph.D. in Anatomy amd Cell, University of North Dakota, Grand Forks, ND, 2012

Current Position

Instructor, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL


  1. Larson-Casey, J. L., Deshane, J. S., Ryan, A. J., Thannickal, V. J. and Carter, A. B. (2016). Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis. Immunity 44(3): 582-596.

  2. He, C., Larson-Casey, J. L., Gu, L., Ryan, A. J., Murthy, S. and Carter, A. B. (2016). Cu,Zn-Superoxide Dismutase-Mediated Redox Regulation of Jumonji Domain Containing 3 Modulates Macrophage Polarization and Pulmonary Fibrosis. Am J Respir Cell Mol Biol 55(1): 58-71.

  3. Slusser-Nore, A., Larson-Casey, J. L., Zhang, R., Zhou, X. D., Somji, S., Garrett, S. H., Sens, D. A. and Dunlevy, J. R. (2016). SPARC Expression Is Selectively Suppressed in Tumor Initiating Urospheres Isolated from As+3- and Cd+2-Transformed Human Urothelial Cells (UROtsa) Stably Transfected with SPARC. PLoS One 11(1): e0147362.

  4. Osborn-Heaford, H. L., Murthy, S., Gu, L., Larson-Casey, J. L., Ryan, A. J., Shi, L., Glogauer, M., Neighbors, J. D., Hohl, R. and Brent Carter, A. (2015). Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosis. Free Radic Biol Med 86: 47-56.

  5. Murthy, S., Larson-Casey, J. L., Ryan, A. J., He, C., Kobzik, L. and Carter, A. B. (2015). Alternative activation of macrophages and pulmonary fibrosis are modulated by scavenger receptor, macrophage receptor with collagenous structure. FASEB J 29(8): 3527-3536.

  6. Larson-Casey, J. L., Murthy, S., Ryan, A. J. and Carter, A. B. (2014). Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis. J Biol Chem 289(52): 36204-36219.

  7. Ryan, A. J., Larson-Casey, J. L., He, C., Murthy, S. and Carter, A. B. (2014). Asbestos-induced disruption of calcium homeostasis induces endoplasmic reticulum stress in macrophages. J Biol Chem 289(48): 33391-33403.

  8. Somji, S., Cao, L., Mehus, A., Zhou, X. D., Sens, M. A., Dunlevy, J. R., Garrett, S. H., Zheng, Y., Larson, J. L. and Sens, D. A. (2011). Comparison of expression patterns of keratin 6, 7, 16, 17, and 19 within multiple independent isolates of As(+3)- and Cd (+2)-induced bladder cancer : keratin 6, 7, 16, 17, and 19 in bladder cancer. Cell Biol Toxicol 27(6): 381-396.

  9. Larson, J., Yasmin, T., Sens, D. A., Zhou, X. D., Sens, M. A., Garrett, S. H., Dunlevy, J. R., Cao, L. and Somji, S. (2010). SPARC gene expression is repressed in human urothelial cells (UROtsa) exposed to or malignantly transformed by cadmium or arsenite. Toxicol Lett 199(2): 166-172.

  10. Larson, J. L., Somji, S., Zhou, X. D., Sens, M. A., Garrett, S. H., Sens, D. A. and Dunlevy, J. R. (2010). Beclin-1 expression in normal bladder and in Cd2+ and As3+ exposed and transformed human urothelial cells (UROtsa). Toxicol Lett 195(1): 15-22.

Protocols by Jennifer L. Larson-Casey
  1. Determination of H2O2 Generation by pHPA Assay
  2. Assay to Evaluate BAL Fluid Regulation of Fibroblast α-SMA Expression