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Tsvetan  Serchov

Tsvetan Serchov


Ph.D. in Neuroscience, International Graduate School of Neuroscience/Department of Molecular Neurchemistry, Ruhr University Bochum, Germany 2007

Current position

Postdoc, Molecular Psychiatry, Department of Psychiatry, University Hospital Freiburg, Germany


  1. Serchov, T., Heumann, R., van Calker, D. and Biber, K. (2016). Signaling pathways regulating Homer1a expression: implications for antidepressant therapy. Biol Chem 397(3): 207-214.

  2. Serchov, T., Clement, H. W., Schwarz, M. K., Iasevoli, F., Tosh, D. K., Idzko, M., Jacobson, K. A., de Bartolomeis, A., Normann, C., Biber, K. and van Calker, D. (2015). Increased Signaling via Adenosine A1 Receptors, Sleep Deprivation, Imipramine, and Ketamine Inhibit Depressive-like Behavior via Induction of Homer1a. Neuron 87(3): 549-562.

  3. Serchov, T., Jilg, A., Wolf, C. T., Radtke, I., Stehle, J. H. and Heumann, R. (2016). Ras Activity Oscillates in the Mouse Suprachiasmatic Nucleus and Modulates Circadian Clock Dynamics. Mol Neurobiol 53(3): 1843-1855.

  4. Shieh, C. H., Heinrich, A., Serchov, T., van Calker, D. and Biber, K. (2014). P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-alpha in cultured mouse microglia. Glia 62(4): 592-607.

  5. Serchov, T., Atas, H. C., Normann, C., van Calker, D. and Biber, K. (2012). Genetically controlled upregulation of adenosine A(1) receptor expression enhances the survival of primary cortical neurons. Mol Neurobiol 46(2): 535-544.

  6. Charlot, C., Dubois-Pot, H., Serchov, T., Tourrette, Y. and Wasylyk, B. (2010). A review of post-translational modifications and subcellular localization of Ets transcription factors: possible connection with cancer and involvement in the hypoxic response. Methods Mol Biol 647: 3-30.

  7. Serchov, T., Dubois-Pot-Schneider, H., Charlot, C., Rosl, F. and Wasylyk, B. (2010). Involvement of net and Hif1alpha in distinct yet intricately linked hypoxia-induced signaling pathways. J Biol Chem 285(28): 21223-21232.

  8. Makwana, M., Serchov, T., Hristova, M., Bohatschek, M., Gschwendtner, A., Kalla, R., Liu, Z., Heumann, R. and Raivich, G. (2009). Regulation and function of neuronal GTP-Ras in facial motor nerve regeneration. J Neurochem 108(6): 1453-1463.

  9. Chakrabarty, K., Serchov, T., Mann, S. A., Dietzel, I. D. and Heumann, R. (2007). Enhancement of dopaminergic properties and protection mediated by neuronal activation of Ras in mouse ventral mesencephalic neurones. Eur J Neurosci 25(7): 1971-1981.

  10. Serchov, T. and Heumann, R. (2006). Constitutive activation of ras in neurons: implications for the regulation of the mammalian circadian clock. Chronobiol Int 23(1-2): 191-200.

Protocols by Tsvetan Serchov
  1. Light/Dark Transition Test to Assess Anxiety-like Behavior in Mice
  2. Sucrose Preference Test to Measure Anhedonic Behaviour in Mice