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Chia-Yu Wang

Education

Ph.D in Nutritional Science, Department of Food Science and Human Nutrition, University of Florida, 2012

Current position

Research Fellow, Program in Anemia Signaling Research, Division of Nephrology, Program in Membrane Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

Publications (since 2003)

  1. Wang, C. Y. and Babitt, J. L. (2016). Hepcidin regulation in the anemia of inflammation. Curr Opin Hematol 23(3): 189-197.

  2. Canali, S., Core, A. B., Zumbrennen-Bullough, K. B., Merkulova, M., Wang, C. Y., Schneyer, A. L., Pietrangelo, A. and Babitt, J. L. (2016). Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice. Endocrinology 157(3): 1146-1162.

  3. Canali, S., Core, A. B., Zumbrennen-Bullough, K. B., Merkulova, M., Wang, C. Y., Schneyer, A. L., Pietrangelo, A. and Babitt, J. L. (2016). Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice. Endocrinology 157(3): 1146-1162.

  4. Jenkitkasemwong, S., Wang, C. Y., Coffey, R., Zhang, W., Chan, A., Biel, T., Kim, J. S., Hojyo, S., Fukada, T. and Knutson, M. D. (2015). SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis. Cell Metab 22(1): 138-150.

  5. Wang, C. Y., Meynard, D. and Lin, H. Y. (2014). The role of TMPRSS6/matriptase-2 in iron regulation and anemia. Front Pharmacol 5: 114.

  6. Guo, X., Zhang, Z., Zhang, F., Tao, Y., An, P., Wu, Q., Wang, C. Y., Knutson, M. D. and Wang, F. (2013). Fine-mapping and genetic analysis of the loci affecting hepatic iron overload in mice. PLoS One 8(5): e63280.

  7. Wang, C. Y. and Knutson, M. D. (2013). Hepatocyte divalent metal-ion transporter-1 is dispensable for hepatic iron accumulation and non-transferrin-bound iron uptake in mice. Hepatology 58(2): 788-798.

  8. Nam, H., Wang, C. Y., Zhang, L., Zhang, W., Hojyo, S., Fukada, T. and Knutson, M. D. (2013). ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders. Haematologica 98(7): 1049-1057.

  9. Wang, C. Y., Jenkitkasemwong, S., Duarte, S., Sparkman, B. K., Shawki, A., Mackenzie, B. and Knutson, M. D. (2012). ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading. J Biol Chem 287(41): 34032-34043.

  10. Jenkitkasemwong, S., Wang, C. Y., Mackenzie, B. and Knutson, M. D. (2012). Physiologic implications of metal-ion transport by ZIP14 and ZIP8. Biometals 25(4): 643-655.

  11. Lyu, L. C., Lo, C. C., Chen, H. F., Wang, C. Y. and Liu, D. M. (2009). A prospective study of dietary intakes and influential factors from pregnancy to postpartum on maternal weight retention in Taipei, Taiwan. Br J Nutr 102(12): 1828-1837.

Protocols by Chia-Yu Wang
  1. Measurement of Transferrin- and Non-transferrin-bound Iron Uptake by Mouse Tissues