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Yuval Rinkevich


Ph.D. in Biology, Technion, Israel Institute of Technology, Haifa

Current position

Young Investigator Group Leader,Institute for Lung Biology and Disease, elmholtz Zentrum Munchen.
Basic Life Science Research Associate, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University.


  1. Corey, D. M., Rinkevich, Y. and Weissman, I. L. (2016). Dynamic Patterns of Clonal Evolution in Tumor Vasculature Underlie Alterations in Lymphocyte-Endothelial Recognition to Foster Tumor Immune Escape. Cancer Res 76(6): 1348-1353.

  2. Walmsley, G. G., Hu, M. S., Maan, Z. N., Rinkevich, Y., Weissman, I. L. and Longaker, M. T. (2015) (Editorial) En1 fibroblasts and melanoma. Melanoma Management, 2(3):191-192. (IF: NA)

  3. Walmsley, G. G., Rinkevich, Y., Hu, M. S., Montoro, D. T., Lo, D. D., McArdle, A., Maan, Z. N., Morrison, S. D., Duscher, D., Whittam, A. J., Wong, V. W., Weissman, I. L., Gurtner, G. C. and Longaker, M. T. (2015). Live fibroblast harvest reveals surface marker shift in vitro. Tissue Eng Part C Methods 21(3): 314-321.

  4. Rinkevich, Y., Walmsley, G. G., Hu, M. S., Maan, Z. N., Newman, A. M., Drukker, M., Januszyk, M., Krampitz, G. W., Gurtner, G. C., Lorenz, H. P., Weissman, I. L. and Longaker, M. T. (2015). Skin fibrosis. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential. Science 348(6232): aaa2151.

  5. Rinkevich, Y., Montoro, D. T., Muhonen, E., Walmsley, G. G., Lo, D., Hasegawa, M., Januszyk, M., Connolly, A. J., Weissman, I. L. and Longaker, M. T. (2014). Clonal analysis reveals nerve-dependent and independent roles on mammalian hind limb tissue maintenance and regeneration. Proc Natl Acad Sci U S A 111(27): 9846-9851.

  6. Rinkevich, Y., Montoro, D. T., Contreras-Trujillo, H., Harari-Steinberg, O., Newman, A. M., Tsai, J. M., Lim, X., Van-Amerongen, R., Bowman, A., Januszyk, M., Pleniceanu, O., Nusse, R., Longaker, M. T., Weissman, I. L. and Dekel, B. (2014). In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration. Cell Rep 7(4): 1270-1283.

  7. Rinkevich, Y., Voskoboynik, A., Rosner, A., Rabinowitz, C., Paz, G., Oren, M., Douek, J., Alfassi, G., Moiseeva, E., Ishizuka, K. J., Palmeri, K. J., Weissman, I. L. and Rinkevich, B. (2013). Repeated, long-term cycling of putative stem cells between niches in a basal chordate. Dev Cell 24(1): 76-88.

  8. Rinkevich, Y., Mori, T., Sahoo, D., Xu, P. X., Bermingham, J. R., Jr. and Weissman, I. L. (2012). Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature. Nat Cell Biol 14(12): 1251-1260.

  9. Drukker, M., Tang, C., Ardehali, R., Rinkevich, Y., Seita, J., Lee, A. S., Mosley, A. R., Weissman, I. L. and Soen, Y. (2012). Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. Nat Biotechnol 30(6): 531-542.

  10. Rinkevich, Y., Lindau, P., Ueno, H., Longaker, M. T. and Weissman, I. L. (2011). Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. Nature 476(7361): 409-413.

  11. Rinkevich, Y., Rosner, A., Rabinowitz, C., Lapidot, Z., Moiseeva, E. and Rinkevich, B. (2010). Piwi positive cells that line the vasculature epithelium, underlie whole body regeneration in a basal chordate. Dev Biol 345(1): 94-104.

  12. Rosner, A., Moiseeva, E., Rinkevich, Y., Lapidot, Z. and Rinkevich, B. (2009). Vasa and the germ line lineage in a colonial urochordate. Dev Biol 331(2): 113-128.

  13. Voskoboynik, A., Soen, Y., Rinkevich, Y., Rosner, A., Ueno, H., Reshef, R., Ishizuka, K. J., Palmeri, K. J., Moiseeva, E., Rinkevich, B. and Weissman, I. L. (2008). Identification of the endostyle as a stem cell niche in a colonial chordate. Cell Stem Cell 3(4): 456-464.

  14. Rinkevich, Y., Rinkevich, B. and Reshef, R. (2008). Cell signaling and transcription factor genes expressed during whole body regeneration in a colonial chordate. BMC Dev Biol 8: 100.

  15. Rinkevich, Y., Paz, G., Rinkevich, B. and Reshef, R. (2007). Systemic bud induction and retinoic acid signaling underlie whole body regeneration in the urochordate Botrylloides leachi. PLoS Biol 5(4): e71.

  16. Rinkevich, Y., Douek, J., Haber, O., Rinkevich, B. and Reshef, R. (2007). Urochordate whole body regeneration inaugurates a diverse innate immune signaling profile. Dev Biol 312(1): 131-146.

  17. Halevy, O., Piestun, Y., Allouh, M. Z., Rosser, B. W., Rinkevich, Y., Reshef, R., Rozenboim, I., Wleklinski-Lee, M. and Yablonka-Reuveni, Z. (2004). Pattern of Pax7 expression during myogenesis in the posthatch chicken establishes a model for satellite cell differentiation and renewal. Dev Dyn 231(3): 489-502.

Protocols by Yuval Rinkevich
  1. Denervation of Mouse Lower Hind Limb by Sciatic and Femoral Nerve Transection