Education
Ph.D. in Biochemisty, Center of Exp. Gynecology & Eicosanoid research, Charité, Berlin & Department of Chemistry, National and Kapodistrian University of Athens, 2008
Current position
Post doctoral fellow, Institute of Pharmacology, Heart Research Center Göttingen (HRCG), University Medical Center Göttingen (UMG), Göttingen
Publications
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Ott, C., Martens, H., Hassouna, I., Oliveira, B., Erck, C., Zafeiriou, M. P., Peteri, U. K., Hesse, D., Gerhart, S., Altas, B., Kolbow, T., Stadler, H., Kawabe, H., Zimmermann, W. H., Nave, K. A., Schulz-Schaeffer, W., Jahn, O. and Ehrenreich, H. (2015). Widespread expression of erythropoietin receptor in brain and its induction by injury. Mol Med.
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Zafiriou, M. P., Noack, C., Unsold, B., Didie, M., Pavlova, E., Fischer, H. J., Reichardt, H. M., Bergmann, M. W., El-Armouche, A., Zimmermann, W. H. and Zelarayan, L. C. (2014). Erythropoietin responsive cardiomyogenic cells contribute to heart repair post myocardial infarction. Stem Cells 32(9): 2480-2491.
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Renger, A., Zafiriou, M. P., Noack, C., Pavlova, E., Becker, A., Sharkova, K., Bergmann, M. W., El-Armouche, A., Zimmermann, W. H. and Zelarayan, L. C. (2013). The four and a half LIM-domain 2 controls early cardiac cell commitment and expansion via regulating beta-catenin-dependent transcription. Stem Cells 31(5): 928-940.
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Zelarayan, L. C., Zafiriou, M. P. and Zimmermann, W. H. (2013). Emerging Concepts in Myocardial Pharmacoregeneration. In: Steinhoff, Gustav (Ed.). Regenerative Medicine- From Protocol to Patient. 25. Netherland: Springer
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Noack, C., Zafiriou, M. P., Schaeffer, H. J., Renger, A., Pavlova, E., Dietz, R., Zimmermann, W. H., Bergmann, M. W. and Zelarayan, L. C. (2012). Krueppel-like factor 15 regulates Wnt/beta-catenin transcription and controls cardiac progenitor cell fate in the postnatal heart. EMBO Mol Med 4(9): 992-1007.
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Zafiriou, M. P., Zelarayan, L. C., Noack, C., Renger, A., Nigam, S. and Siafaka-Kapadai, A. (2011). Hepoxilin A(3) protects beta-cells from apoptosis in contrast to its precursor, 12-hydroperoxyeicosatetraenoic acid. Biochim Biophys Acta 1811(6): 361-369.
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Zelarayan, L. C., Noack, C., Zafiriou, M. P., Renger, A. and Bergmann, M. W. (2010). Wnt signaling molecules in left ventricular remodeling: focus on dishevelled 1. Hypertension 55(4): 852-854.
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Deva, R., Sczepanski, M., Saha, S., Zafiriou, M. P., Kerstin, N., Jakobsson, P. J., Inoue, Y. and Nigam, S. (2010). C. albicans activates cyclooxygenase but not its product prostaglandin E(2)in HPV 16-stabilized cells. Eur J Obstet Gynecol Reprod Biol 152(2): 205-209.
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Zelarayan, L., Renger, A., Noack, C., Zafiriou, M. P., Gehrke, C., van der Nagel, R., Dietz, R., de Windt, L. and Bergmann, M. W. (2009). NF-kappaB activation is required for adaptive cardiac hypertrophy. Cardiovasc Res 84(3): 416-424.
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Zelarayan, L. C., Noack, C., Sekkali, B., Kmecova, J., Gehrke, C., Renger, A., Zafiriou, M. P., van der Nagel, R., Dietz, R., de Windt, L. J., Balligand, J. L. and Bergmann, M. W. (2008). Beta-Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation. Proc Natl Acad Sci U S A 105(50): 19762-19767.
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Nigam, S., Zafiriou, M. P., Deva, R., Kerstin, N., Geilen, C., Ciccoli, R., Sczepanski, M. and Lohse, M. (2008). Hepoxilin A3 (HXA3) synthase deficiency is causative of a novel ichthyosis form. FEBS Lett 582(2): 279-285.
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Zafiriou, M. P., Deva, R., Ciccoli, R., Siafaka-Kapadai, A. and Nigam, S. (2007). Biological role of hepoxilins: upregulation of phospholipid hydroperoxide glutathione peroxidase as a cellular response to oxidative stress? Prostaglandins Leukot Essent Fatty Acids 77(3-4): 209-215.
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Nigam, S., Zafiriou, M. P., Deva, R., Ciccoli, R. and Roux-Van der Merwe, R. (2007). Structure, biochemistry and biology of hepoxilins: an update. FEBS J 274(14): 3503-3512.
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Ciccoli, R., Sahi, S., Singh, S., Prakash, H., Zafiriou, M. P., Ishdorj, G., Kock, J. L. and Nigam, S. (2005). Oxygenation by COX-2 (cyclo-oxygenase-2) of 3-HETE (3-hydroxyeicosatetraenoic acid), a fungal mimetic of arachidonic acid, produces a cascade of novel bioactive 3-hydroxyeicosanoids. Biochem J 390(Pt 3): 737-747.
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Karava, V., Zafiriou, P. M., Fasia, L., Anagnostopoulos, D., Boutou, E., Vorgias, C. E., Maccarrone, M. and Siafaka-Kapadai, A. (2005). Anandamide metabolism by Tetrahymena pyriformis in vitro. Characterization and identification of a 66 kDa fatty acid amidohydrolase. Biochimie 87(11): 967-974.
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Nigam, S. and Zafiriou, M. P. (2005). Hepoxilin A3 synthase. Biochem Biophys Res Commun 338(1): 161-168.