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Sébastien  Gillotin

Sébastien Gillotin


Ph.D. in Biochemistry, Department of Medicine, Imperial College London, 2007

Current position

Senior Reseach Associate, University of Cambridge, UK


  1. Masserdotti, G.^, Gillotin, S.^, Sutor, B., Drechsel, D., Irmler, M., Jorgensen, H. F., Sass, S., Theis, F. J., Beckers, J., Berninger, B., Guillemot, F. and Gotz, M*. (2015). Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes. Cell Stem Cell 17(1): 74-88. ^Equally contributing authors, *Corresponding authors
  2. Raposo, A. A., Vasconcelos, F. F., Drechsel, D., Marie, C., Johnston, C., Dolle, D., Bithell, A., Gillotin, S., van den Berg, D. L., Ettwiller, L., Flicek, P., Crawford, G. E., Parras, C. M., Berninger, B., Buckley, N. J., Guillemot, F. and Castro, D. S. (2015). Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis. Cell Rep.
  3. Gillotin, S. and Lu, X. (2011). The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53. FEBS Lett 585(12): 1778-1782.
  4. Gillotin, S., Yap, D. and Lu, X. (2010). Mutation at Ser392 specifically sensitizes mutant p53H175 to mdm2-mediated degradation. Cell Cycle 9(7): 1390-1398.
  5. Gillotin, S. (2009). iASPP, a potential drug target in cancer therapy. Leuk Res 33(9): 1175-1177.
  6. Slee, E. A., Gillotin, S., Bergamaschi, D., Royer, C., Llanos, S., Ali, S., Jin, B., Trigiante, G. and Lu, X. (2004). The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization. Oncogene 23(56): 9007-9016.
Protocols by Sébastien Gillotin
  1. Micro-chromatin Immunoprecipation (μChIP) Protocol for Real-time PCR Analysis of a Limited Amount of Cells