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Martin  Zacharias

Martin Zacharias


Ph.D. in Biophysics, Free University of Berlin, 1991
Habilitation in Biophysics, Humboldt University of Berlin, 1999

Current position

Professor of Theoretical Biophysics, Technical University of Munich, Germany

Publications (selected)

  1. Pelz, B., Žoldák, G., Zeller, F., Zacharias, M. and Rief, M. (2016). Subnanometre enzyme mechanics probed by single-molecule force spectroscopy. Nat Commun 7: 10848.
  2. Schindler, C. E., de Vries, S. J. and Zacharias, M. (2015). Fully Blind Peptide-Protein Docking with pepATTRACT. Structure 23(8): 1507-1515.
  3. de Vries, S. J., Schindler, C. E., Chauvot de Beauchêne, I. and Zacharias, M. (2015). A web interface for easy flexible protein-protein docking with ATTRACT. Biophys J 108(3): 462-465.
  4. Ostermeir, K. and Zacharias, M. (2014). Hamiltonian replica-exchange simulations with adaptive biasing of peptide backbone and side chain dihedral angles. J Comput Chem 35(2): 150-158.
  5. Kannan, S. and Zacharias, M. (2014). Role of tryptophan side chain dynamics on the Trp-cage mini-protein folding studied by molecular dynamics simulations. PLoS One 9(2): e88383.
  6. Braun, N., Zacharias, M., Peschek, J., Kastenmuller, A., Zou, J., Hanzlik, M., Haslbeck, M., Rappsilber, J., Buchner, J. and Weinkauf, S. (2011). Multiple molecular architectures of the eye lens chaperone alphaB-crystallin elucidated by a triple hybrid approach. Proc Natl Acad Sci U S A 108(51): 20491-20496.
  7. Zeller, F. and Zacharias, M. (2014). Adaptive Biasing Combined with Hamiltonian Replica Exchange to Improve Umbrella Sampling Free Energy Simulations. J Chem Theory Comput 10(2): 703-710.
  8. Saini, S. K., Ostermeir, K., Ramnarayan, V. R., Schuster, H., Zacharias, M. and Springer, S. (2013). Dipeptides promote folding and peptide binding of MHC class I molecules. Proc Natl Acad Sci U S A 110(38): 15383-15388.
Protocols by Martin Zacharias
  1. Development and Application of a Fully Blind Flexible Peptide-protein Docking Protocol, pepATTRACT