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Masamitsu Tanaka

Education

M.D. in Hamamatsu University School of Medicine, 1992

Current position

Professor in Molecular Medicine and Biochemistry, Akita University Graduate School of Medicine, Akita, Japan

Publications (since 2007)

  1. Tanaka, M., Kuriyama, S., Itoh, G., Kohyama, A., Iwabuchi, Y., Shibata, H., Yashiro, M. and Aiba, N. (2016). Identification of anti-cancer chemical compounds using Xenopus embryos. Cancer Sci.
  2. Tanaka, M., Shimamura, S., Kuriyama, S., Maeda, D., Goto, A. and Aiba, N. (2016). SKAP2 Promotes Podosome Formation to Facilitate Tumor-Associated Macrophage Infiltration and Metastatic Progression. Cancer Res 76(2): 358-369.
  3. Kuriyama, S., Yoshida, M., Yano, S., Aiba, N., Kohno, T., Minamiya, Y., Goto, A. and Tanaka, M. (2016). LPP inhibits collective cell migration during lung cancer dissemination. Oncogene 35(8): 952-964.
  4. Sugiyama, S., Yoshino, Y., Kuriyama, S., Inoue, M., Komine, K., Otsuka, K., Kohyama, A., Yamakoshi, H., Ishioka, C., Tanaka, M., Iwabuchi, Y. and Shibata, H. (2016). A Curcumin Analog, GO-Y078, Effectively Inhibits Angiogenesis through Actin Disorganization. Anticancer Agents Med Chem 16(5): 633-647.
  5. Tsuji, T., Satoyoshi, R., Aiba, N., Kubo, T., Yanagihara, K., Maeda, D., Goto, A., Ishikawa, K., Yashiro, M. and Tanaka, M. (2015). Agr2 mediates paracrine effects on stromal fibroblasts that promote invasion by gastric signet-ring carcinoma cells. Cancer Res 75(2): 356-366.
  6. Satoyoshi, R., Aiba, N., Yanagihara, K., Yashiro, M. and Tanaka, M. (2015). Tks5 activation in mesothelial cells creates invasion front of peritoneal carcinomatosis. Oncogene 34(24): 3176-3187.
  7. Satoyoshi, R., Kuriyama, S., Aiba, N., Yashiro, M. and Tanaka, M. (2015). Asporin activates coordinated invasion of scirrhous gastric cancer and cancer-associated fibroblasts. Oncogene 34(5): 650-660.
  8. Kuriyama, S., Theveneau, E., Benedetto, A., Parsons, M., Tanaka, M., Charras, G., Kabla, A. and Mayor, R. (2014). In vivo collective cell migration requires an LPAR2-dependent increase in tissue fluidity. J Cell Biol 206(1): 113-127.
  9. Shimamura, S., Sasaki, K. and Tanaka, M. (2013). The Src substrate SKAP2 regulates actin assembly by interacting with WAVE2 and cortactin proteins. J Biol Chem 288(2): 1171-1183.
  10. Tanaka, M., Kuriyama, S. and Aiba, N. (2012). Nm23-H1 regulates contact inhibition of locomotion, which is affected by ephrin-B1. J Cell Sci 125(Pt 18): 4343-4353.
  11. Otsuka, K., Satoyoshi, R., Nanjo, H., Miyazawa, H., Abe, Y., Tanaka, M., Yamamoto, Y. and Shibata, H. (2012). Acquired/intratumoral mutation of KRAS during metastatic progression of colorectal carcinogenesis. Oncol Lett 3(3): 649-653.
  12. Yagi, R., Tanaka, M., Sasaki, K., Kamata, R., Nakanishi, Y., Kanai, Y. and Sakai, R. (2011). ARAP3 inhibits peritoneal dissemination of scirrhous gastric carcinoma cells by regulating cell adhesion and invasion. Oncogene 30(12): 1413-1421.
  13. Tanaka, M., Kamata, R., Yanagihara, K. and Sakai, R. (2010). Suppression of gastric cancer dissemination by ephrin-B1-derived peptide. Cancer Sci 101(1): 87-93.
  14. Tanaka, M., Sasaki, K., Kamata, R., Hoshino, Y., Yanagihara, K. and Sakai, R. (2009). A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis. Mol Cell Biol 29(2): 402-413.
  15. Uekita, T., Tanaka, M., Takigahira, M., Miyazawa, Y., Nakanishi, Y., Kanai, Y., Yanagihara, K. and Sakai, R. (2008). CUB-domain-containing protein 1 regulates peritoneal dissemination of gastric scirrhous carcinoma. Am J Pathol 172(6): 1729-1739.
  16. Tanaka, M., Sasaki, K., Kamata, R. and Sakai, R. (2007). The C-terminus of ephrin-B1 regulates metalloproteinase secretion and invasion of cancer cells. J Cell Sci 120(Pt 13): 2179-2189.
  17. Tanaka, M., Kamata, R., Takigahira, M., Yanagihara, K. and Sakai, R. (2007). Phosphorylation of ephrin-B1 regulates dissemination of gastric scirrhous carcinoma. Am J Pathol 171(1): 68-78.
Protocols by Masamitsu Tanaka
  1. 3D Gel Invasion Assay of Gastric Cancer cells with Fibroblasts