Welcome guest, Login | Register

Home


Chang-Duk Jun

Education

Ph.D. in Immunology, Kyungpook National University, 1996

Current position

Professor, School of Life Sciences, Gwangju Institute of Science and Technology

Publication (since 2011)

  1. Kim, C. H., Kim, Y. D., Choi, E. K., Kim, H. R., Na, B. R., Im, S. H. and Jun, C. D. (2016). Nuclear Speckle-Related Protein 70 Binds to Serine/Arginine-Rich Splicing Factor-1 and -2 Via an Arginine/Serine-Like Region and Counteracts Their Alternative Splicing Activity. J Biol Chem. (Epub ahead of print)
  2. Kwon, H. K., Kim, G. C., Hwang, J. S., Kim, Y., Chae, C. S., Nam, J. H., Jun, C. D., Rudra, D., Surh, C. D. and Im, S. H. (2016). Transcription factor NFAT1 controls allergic contact hypersensitivity through regulation of activation induced cell death program. Sci Rep 6: 19453.
  3. Lee, H. S., Choi, E. J., Choi, H., Lee, K. S., Kim, H. R., Na, B. R., Kwon, M. S., Jeong, G. S., Choi, H. G., Choi, E. Y. and Jun, C. D. (2015). Oral Administration of 4-Hydroxy-3-Methoxycinnamaldehyde Attenuates Atopic Dermatitis by Inhibiting T Cell and Keratinocyte Activation. PLoS One 10(12): e0144521.
  4. Na, B. R. and Jun, C. D. (2015). TAGLN2-mediated actin stabilization at the immunological synapse: implication for cytotoxic T cell control of target cells. BMB Rep 48(7): 369-370.
  5. Na, B. R., Kim, H. R., Piragyte, I., Oh, H. M., Kwon, M. S., Akber, U., Lee, H. S., Park, D. S., Song, W. K., Park, Z. Y., Im, S. H., Rho, M. C., Hyun, Y. M., Kim, M. and Jun, C. D. (2015). TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse. J Cell Biol 209(1): 143-162.
  6. Jang, S. H., Jun, C. D. and Park, Z. Y. (2015). Label-free quantitative phosphorylation analysis of human transgelin2 in Jurkat T cells reveals distinct phosphorylation patterns under PKA and PKC activation conditions. Proteome Sci 13: 14.
  7. Akber, U., Na, B. R., Ko, Y. S., Lee, H. S., Kim, H. R., Kwon, M. S., Park, Z. Y., Choi, E. J., Han, W. C., Lee, S. H., Oh, H. M. and Jun, C. D. (2015). Phytocomponent 4-hydroxy-3-methoxycinnamaldehyde ablates T-cell activation by targeting protein kinase C-θ and its downstream pathways. Int Immunopharmacol 25(1): 130-140.
  8. Hwang, J. S., Kim, G. C., Park, E., Kim, J. E., Chae, C. S., Hwang, W., Lee, C., Hwang, S. M., Wang, H. S., Jun, C. D., Rudra, D. and Im, S. H. (2015). NFAT1 and JunB cooperatively regulate IL-31 gene expression in CD4+ T cells in health and disease. J Immunol 194(4): 1963-1974.
  9. Choi, D. B., Park, M. R., Kim, H. R., Jun, C. D., Kim, H. J., Shim, H., Kim, Y. D., Choi, C., Choi, K. H., Yun, K. J., Chae, S. C., Park, R., Choe, S. K., Lee, Y. J. and Park, D. S. (2014). Aberrant proteomic expression of NSRP70 and its clinical implications and connection to the transcriptional level in adult acute leukemia. Leuk Res 38(10): 1252-1259.
  10. So, J. S., Kim, G. C., Song, M., Lee, C. G., Park, E., Kim, H. J., Kim, Y. S., Jun, C. D. and Im, S. H. (2014). 6-Methoxyflavone inhibits NFAT translocation into the nucleus and suppresses T cell activation. J Immunol 193(6): 2772-2783.
  11. Park, S. H., Kim, H. R., Jun, C. D., Song, W. K. and Park, S. G. (2014). Spin90 deficiency increases CXCL13-mediated B cell migration. Scand J Immunol 80(3): 191-197.
  12. Kwon, M. S., Park, K. R., Kim, Y. D., Na, B. R., Kim, H. R., Choi, H. J., Piragyte, I., Jeon, H., Chung, K. H., Song, W. K., Eom, S. H. and Jun, C. D. (2013). Swiprosin-1 is a novel actin bundling protein that regulates cell spreading and migration. PLoS One 8(8): e71626.
  13. Huh, Y. H., Kim, S. H., Chung, K. H., Oh, S., Kwon, M. S., Choi, H. W., Rhee, S., Ryu, J. H., Park, Z. Y., Jun, C. D. and Song, W. K. (2013). Swiprosin-1 modulates actin dynamics by regulating the F-actin accessibility to cofilin. Cell Mol Life Sci 70(24): 4841-4854.
  14. Na, B. R., Kim, H. R., Kwon, M. S., Lee, H. S., Piragyte, I., Choi, E. J., Choi, H. K., Han, W. C., Lee, S. H. and Jun, C. D. (2013). Aplotaxene blocks T cell activation by modulation of protein kinase C-θ-dependent pathway. Food Chem Toxicol 62: 23-31.
  15. Kim, H. R., Na, B. R., Kwon, M. S., Ko, Y. S., Han, W. C. and Jun, C. D. (2013). Dynamic motile T cells highly respond to the T cell stimulation via PI3K-Akt and NF-kappaB pathways. PLoS One 8(3): e59793.
  16. Park, H. Y., Jun, C. D., Jeon, S. J., Choi, S. S., Kim, H. R., Choi, D. B., Kwak, S., Lee, H. S., Cheong, J. S., So, H. S., Lee, Y. J. and Park, D. S. (2012). Serum YKL-40 levels correlate with infarct volume, stroke severity, and functional outcome in acute ischemic stroke patients. PLoS One 7(12): e51722.
  17. Kim, H. R., Jun, C. D., Lee, K. S., Cho, J. H., Jeong, E. T., Yang, S. H., Lee, Y. J. and Park, D. S. (2012). Levels of YKL-40 in pleural effusions and blood from patients with pulmonary or pleural disease. Cytokine 58(3): 336-343.
  18. Lee, H. S., Kim, Y. D., Na, B. R., Kim, H. R., Choi, E. J., Han, W. C., Choi, H. K., Lee, S. H. and Jun, C. D. (2012). Phytocomponent p-Hydroxycinnamic acid inhibits T-cell activation by modulation of protein kinase C-θ-dependent pathway. Int Immunopharmacol 12(1): 131-138.
  19. Kim, H. R., Jeon, B. H., Lee, H. S., Im, S. H., Araki, M., Araki, K., Yamamura, K., Choi, S. C., Park, D. S. and Jun, C. D. (2011). IGSF4 is a novel TCR z-chain-interacting protein that enhances TCR-mediated signaling. J Exp Med 208(12): 2545-2560.
  20. Choi, H., Lee, S., Jun, C. D. and Park, Z. Y. (2011). Development of an off-line capillary column IMAC phosphopeptide enrichment method for label-free phosphorylation relative quantification. J Chromatogr B Analyt Technol Biomed Life Sci 879(28): 2991-2997.
  21. Choi, E. J., Lee, S., Chae, J. R., Lee, H. S., Jun, C. D. and Kim, S. H. (2011). Eupatilin inhibits lipopolysaccharide-induced expression of inflammatory mediators in macrophages. Life Sci 88(25-26): 1121-1126.
  22. Choi, E. J., Lee, S., Hwang, J. S., Im, S. H., Jun, C. D., Lee, H. S. and Kim, S. H. (2011). DA-9601 suppresses 2, 4-dinitrochlorobenzene and dust mite extract-induced atopic dermatitis-like skin lesions. Int Immunopharmacol 11(9): 1260-1264.
  23. Kim, Y. D., Lee, J. Y., Oh, K. M., Araki, M., Araki, K., Yamamura, K. and Jun, C. D. (2011). NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo. Nucleic Acids Res 39(10): 4300-4314.
  24. Oh, H. M., Kwon, M. S., Kim, H. J., Jeon, B. H., Kim, H. R., Choi, H. O., Na, B. R., Eom, S. H., Song, N. W. and Jun, C. D. (2011). Intermediate monomer-dimer equilibrium structure of native ICAM-1: implication for enhanced cell adhesion. Exp Cell Res 317(2): 163-172.

Protocols by Chang-Duk Jun
  1. In vitro Assessment of Immunological Synapse Formation by Flow Cytometry