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Gerhard H. Braus

Education

Ph.D. in Microbiology, Swiss Federal Institute of Technology (ETH) Zürich, Switzerland, 1987

Current position

Professor of Molecular Microbiology and Genetics, Georg-August Univesität Göttingen

Publications (more than 200)

10 selected publications and 5 selected reviews:

  1. Lin, C. J., Sasse, C., Gerke, J., Valerius, O., Irmer, H., Frauendorf, H., Heinekamp, T., Strassburger, M., Tran, V. T., Herzog, B., Braus-Stromeyer, S. A. and Braus, G. H. (2015). Transcription Factor SomA Is Required for Adhesion, Development and Virulence of the Human Pathogen Aspergillus fumigatus. PLoS Pathog 11(11): e1005205.
  2. Sarikaya-Bayram, O., Bayram, O., Feussner, K., Kim, J. H., Kim, H. S., Kaever, A., Feussner, I., Chae, K. S., Han, D. M., Han, K. H. and Braus, G. H. (2014). Membrane-bound methyltransferase complex VapA-VipC-VapB guides epigenetic control of fungal development. Dev Cell 29(4): 406-420. (Journal cover)
  3. Ahmed, Y. L., Gerke, J., Park, H. S., Bayram, Ö., Neumann, P., Ni, M., Dickmanns, A., Kim, S. C., Yu, J. H.#, Braus, G. H.# and Ficner, R# (2013). The velvet family of fungal regulators contains a DNA-binding domain structurally similar to NF-kappaB. PLoS Biol 11(12): e1001750. (#Corresponding authors)
  4. Christmann, M., Schmaler, T., Gordon, C., Huang, X., Bayram, O., Schinke, J., Stumpf, S., Dubiel, W. and Braus, G. H. (2013). Control of multicellular development by the physically interacting deneddylases DEN1/DenA and COP9 signalosome. PLoS Genet 9(2): e1003275.
  5. Bayram, O., Bayram, O. S., Ahmed, Y. L., Maruyama, J., Valerius, O., Rizzoli, S. O., Ficner, R., Irniger, S. and Braus, G. H. (2012). The Aspergillus nidulans MAPK module AnSte11-Ste50-Ste7-Fus3 controls development and secondary metabolism. PLoS Genet 8(7): e1002816. (Journal cover)
  6. Sarikaya Bayram, O., Bayram, O., Valerius, O., Park, H. S., Irniger, S., Gerke, J., Ni, M., Han, K. H., Yu, J. H. and Braus, G. H. (2010). LaeA control of velvet family regulatory proteins for light-dependent development and fungal cell-type specificity. PLoS Genet 6(12): e1001226. (Journal cover)
  7. Bayram, O., Krappmann, S., Ni, M., Bok, J. W., Helmstaedt, K., Valerius, O., Braus-Stromeyer, S., Kwon, N. J., Keller, N. P., Yu, J. H. and Braus, G. H. (2008). VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism. Science 320(5882): 1504-1506.
  8. Busch, S., Schwier, E. U., Nahlik, K., Bayram, O., Helmstaedt, K., Draht, O. W., Krappmann, S., Valerius, O., Lipscomb, W. N. and Braus, G. H. (2007). An eight-subunit COP9 signalosome with an intact JAMM motif is required for fungal fruit body formation. Proc Natl Acad Sci U S A 104(19): 8089-8094.
  9. alagan, J. E., Calvo, S. E., Cuomo, C., Ma, L. J., Wortman, J. R., Batzoglou, S., Lee, S. I., Basturkmen, M., Spevak, C. C., Clutterbuck, J., Kapitonov, V., Jurka, J., Scazzocchio, C., Farman, M., Butler, J., Purcell, S., Harris, S., Braus, G. H., Draht, O., Busch, S., D'Enfert, C., Bouchier, C., Goldman, G. H., Bell-Pedersen, D., Griffiths-Jones, S., Doonan, J. H., Yu, J., Vienken, K., Pain, A., Freitag, M., Selker, E. U., Archer, D. B., Penalva, M. A., Oakley, B. R., Momany, M., Tanaka, T., Kumagai, T., Asai, K., Machida, M., Nierman, W. C., Denning, D. W., Caddick, M., Hynes, M., Paoletti, M., Fischer, R., Miller, B., Dyer, P., Sachs, M. S., Osmani, S. A. and Birren, B. W. (2005). Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae. Nature 438(7071): 1105-1115.
  10. Helmstaedt, K., Strittmatter, A., Lipscomb, W. N. and Braus, G. H. (2005). Evolution of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase-encoding genes in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 102(28): 9784-9789.

Selected reviews:

  1. Popova, B., Kleinknecht, A. and Braus, G. H. (2015). Posttranslational Modifications and Clearing of α-Synuclein Aggregates in Yeast. Biomolecules 5(2): 617-634.
  2. Sarikaya-Bayram, O., Palmer, J. M., Keller, N., Braus, G. H. and Bayram, O. (2015). One Juliet and four Romeos: VeA and its methyltransferases. Front Microbiol 6: 1.
  3. Bayram, O. and Braus, G. H. (2012). Coordination of secondary metabolism and development in fungi: the velvet family of regulatory proteins. FEMS Microbiol Rev 36(1): 1-24.
  4. Braus, G. H., Irniger, S. and Bayram, O. (2010). Fungal development and the COP9 signalosome. Curr Opin Microbiol 13(6): 672-676.
  5. Bayram, O., Braus, G. H., Fischer, R. and Rodriguez-Romero, J. (2010). Spotlight on Aspergillus nidulans photosensory systems. Fungal Genet Biol 47(11): 900-908.
Protocols by Gerhard H. Braus
  1. In vitro Deneddylation Assay