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Sangeeta Bhaskar

Education

Ph.D. in JNU, 1999

Current position

Staff Scientist VI, National Institute of Immunology

Publications (selected)

  1. Kumar, P., John, V., Marathe, S., Das, G. and Bhaskar, S. (2015). Mycobacterium indicus pranii induces dendritic cell activation, survival, and Th1/Th17 polarization potential in a TLR-dependent manner. J Leukoc Biol 97(3): 511-520.
  2. Kumar, P., Tyagi, R., Das, G. and Bhaskar, S. (2014). Mycobacterium indicus pranii and Mycobacterium bovis BCG lead to differential macrophage activation in Toll-like receptor-dependent manner. Immunology 143(2): 258-268.
  3.  Singh, M. S. and Bhaskar, S.* (2014). Nanocarrier-based immunotherapy in cancer management and research. Immuno Targets and Therapy 3:121-134.
  4. Roy, A., Singh, M. S., Upadhyay, P. and Bhaskar, S. (2013). Nanoparticle mediated co-delivery of paclitaxel and a TLR-4 agonist results in tumor regression and enhanced immune response in the tumor microenvironment of a mouse model. Int J Pharm 445(1-2): 171-180.
  5. Gupta, A., Ahmad, F. J., Ahmad, F., Gupta, U. D., Natarajan, M., Katoch, V. M. and Bhaskar, S. (2012). Protective efficacy of Mycobacterium indicus pranii against tuberculosis and underlying local lung immune responses in guinea pig model. Vaccine 30(43): 6198-6209.
  6. Gupta, A., Ahmad, F. J., Ahmad, F., Gupta, U. D., Natarajan, M., Katoch, V. and Bhaskar, S. (2012). Efficacy of Mycobacterium indicus pranii immunotherapy as an adjunct to chemotherapy for tuberculosis and underlying immune responses in the lung. PLoS One 7(7): e39215.
  7. Roy, A., Chandra, S., Mamilapally, S., Upadhyay, P. and Bhaskar, S. (2012). Anticancer and immunostimulatory activity by conjugate of paclitaxel and non-toxic derivative of LPS for combined chemo-immunotherapy. Pharm Res 29(8): 2294-2309.
  8. Ahmad, F., Mani, J., Kumar, P., Haridas, S., Upadhyay, P. and Bhaskar, S. (2011). Activation of anti-tumor immune response and reduction of regulatory T cells with Mycobacterium indicus pranii (MIP) therapy in tumor bearing mice. PLoS One 6(9): e25424.
  9. Roy, A., Singh, M. S., Upadhyay, P. and Bhaskar, S. (2010). Combined chemo-immunotherapy as a prospective strategy to combat cancer: a nanoparticle based approach. Mol Pharm 7(5): 1778-1788.
  10. Gupta, A., Geetha, N., Mani, J., Upadhyay, P., Katoch, V. M., Natrajan, M., Gupta, U. D. and Bhaskar, S. (2009). Immunogenicity and protective efficacy of "Mycobacterium w" against Mycobacterium tuberculosis in mice immunized with live versus heat-killed M. w by the aerosol or parenteral route. Infect Immun 77(1): 223-231.
  11. Upadhyay, P., Hanif, M. and Bhaskar, S. (2006). Visual detection of IS6110 of Mycobacterium tuberculosis in sputum samples using a test based on colloidal gold and latex beads. Clin Microbiol Infect 12(11): 1118-1122.
  12. Bhaskar, S., Banavaliker, J. N. and Hanif, M. (2003). Large-scale validation of a latex agglutination test for diagnosis of tuberculosis. FEMS Immunol Med Microbiol 39(3): 235-239.
  13. Bhaskar, S. and Upadhyay, P. (2003). Design and evaluation of an aerosol infection chamber for small animals. Int J Pharm 255(1-2): 43-48.
  14. Bhaskar, S., Banavaliker, J. N., Bhardwaj, K. and Upadhyay, P. (2002). A novel ultrasound-enhanced latex agglutination test for the detection of antibodies against Mycobacterium tuberculosis in serum. J Immunol Methods 262(1-2): 181-186.
  15. Bhaskar, S., Khanna, S. P. and Mukherjee, R. (2000). Isolation, purification and immunological characterization of novel low molecular weight protein antigen CFP 6 from culture filtrate of M. tuberculosis. Vaccine 18(25): 2856-2866.
  16. Bhaskar, S., Dutt, S. and Mukherjee, R. (2000). A simple method of electroelution of individual protein bands from SDS polyacrylamide gels for direct study in cellular assays. J Immunoassay 21(4): 355-375.
  17. Upadhyay, P. and Bhaskar, S. (2000). Real time monitoring of lymphocyte proliferation by an impedance method. J Immunol Methods 244(1-2): 133-137.
Protocols by Sangeeta Bhaskar
  1. Analysis of T Cell Proliferating and Polarizing Potential of Murine Dendritic Cells in Allogeneic-mixed Leukocyte Reaction
  2. Isolation of Genomic DNA from Mycobacterium Species