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Anna Campalans


Ph.D. in Biology, University of Barcelona, 2000

Current position

Permanent Researcher, CEA, Fontenay aux Roses, France

Publications (since 2005)

  1. de Melo, J. T., de Souza Timoteo, A. R., Lajus, T. B., Brandao, J. A., de Souza-Pinto, N. C., Menck, C. F., Campalans, A., Radicella, J. P., Vessoni, A. T., Muotri, A. R. and Agnez-Lima, L. F. (2016). XPC deficiency is related to APE1 and OGG1 expression and function. Mutat Res 784-785: 25-33.
  2. Guyon, L., Lajaunie, C., Fer, F., Bhajun, R., Sulpice, E., Pinna, G., Campalans, A., Radicella, J. P., Rouillier, P., Mary, M., Combe, S., Obeid, P., Vert, J. P. and Gidrol, X. (2015). Phi-score: A cell-to-cell phenotypic scoring method for sensitive and selective hit discovery in cell-based assays. Sci Rep 5: 14221.
  3. Campalans, A., Moritz, E., Kortulewski, T., Biard, D., Epe, B. and Radicella, J. P. (2015). Interaction with OGG1 is required for efficient recruitment of XRCC1 to base excision repair and maintenance of genetic stability after exposure to oxidative stress. Mol Cell Biol 35(9): 1648-1658.
  4. Castillo, D. S., Campalans, A., Belluscio, L. M., Carcagno, A. L., Radicella, J. P., Canepa, E. T. and Pregi, N. (2015). E2F1 and E2F2 induction in response to DNA damage preserves genomic stability in neuronal cells. Cell Cycle 14(8): 1300-1314.
  5. Campalans, A., Kortulewski, T., Amouroux, R., Menoni, H., Vermeulen, W. and Radicella, J. P. (2013). Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair. Nucleic Acids Res 41(5): 3115-3129.
  6. Fantini, D., Moritz, E., Auvre, F., Amouroux, R., Campalans, A., Epe, B., Bravard, A. and Radicella, J. P. (2013). Rapid inactivation and proteasome-mediated degradation of OGG1 contribute to the synergistic effect of hyperthermia on genotoxic treatments. DNA Repair (Amst) 12(3): 227-237.
  7. Amouroux, R., Campalans, A., Epe, B. and Radicella, J. P. (2010). Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions. Nucleic Acids Res 38(9): 2878-2890.
  8. Laporte, P., Satiat-Jeunemaitre, B., Velasco, I., Csorba, T., Van de Velde, W., Campalans, A., Burgyan, J., Arevalo-Rodriguez, M. and Crespi, M. (2010). A novel RNA-binding peptide regulates the establishment of the Medicago truncatula-Sinorhizobium meliloti nitrogen-fixing symbiosis. Plant J 62(1): 24-38.
  9. Bravard, A., Campalans, A., Vacher, M., Gouget, B., Levalois, C., Chevillard, S. and Radicella, J. P. (2010). Inactivation by oxidation and recruitment into stress granules of hOGG1 but not APE1 in human cells exposed to sub-lethal concentrations of cadmium. Mutat Res 685(1-2): 61-69.
  10. Bigot, K., Leemput, J., Vacher, M., Campalans, A., Radicella, J. P., Lacassagne, E., Provost, A., Masson, C., Menasche, M. and Abitbol, M. (2009). Expression of 8-oxoguanine DNA glycosylase (Ogg1) in mouse retina. Mol Vis 15: 1139-1152.
  11. Campalans, A., Amouroux, R., Bravard, A., Epe, B. and Radicella, J. P. (2007). UVA irradiation induces relocalisation of the DNA repair protein hOGG1 to nuclear speckles. J Cell Sci 120(Pt 1): 23-32.
  12. Campalans, A., Marsin, S., Nakabeppu, Y., O'Connor T, R., Boiteux, S. and Radicella, J. P. (2005). XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair. DNA Repair (Amst) 4(7): 826-835.
Protocols by Anna Campalans
  1. Laser Microirradiation and Temporal Analysis of XRCC1 Recruitment to Single-strand DNA Breaks