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Mary Beth Mudgett

Education

Ph.D. in Biochemistry, University of California at Los Angeles, California, 1994

Current position

Professor, Department of Biology, Stanford University (09/15-present)

Publications

  1. Stork, W., Kim, J. G. and Mudgett, M. B. (2015). Functional Analysis of Plant Defense Suppression and Activation by the Xanthomonas Core Type III Effector XopX. Mol Plant Microbe Interact 28(2): 180-194.
  2. Murphy, J. M., Zhang, Q., Young, S. N., Reese, M. L., Bailey, F. P., Eyers, P. A., Ungureanu, D., Hammaren, H., Silvennoinen, O., Varghese, L. N., Chen, K., Tripaydonis, A., Jura, N., Fukuda, K., Qin, J., Nimchuk, Z., Mudgett, M. B., Elowe, S., Gee, C. L., Liu, L., Daly, R. J., Manning, G., Babon, J. J. and Lucet, I. S. (2014). A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties. Biochem J 457(2): 323-334.
  3. Teper, D., Salomon, D., Sunitha, S., Kim, J. G., Mudgett, M. B. and Sessa, G. (2014). Xanthomonas euvesicatoria type III effector XopQ interacts with tomato and pepper 14-3-3 isoforms to suppress effector-triggered immunity. Plant J 77(2): 297-309.
  4. Cheong, M. S., Kirik, A., Kim, J. G., Frame, K., Kirik, V. and Mudgett, M. B. (2014). AvrBsT acetylates Arabidopsis ACIP1, a protein that associates with microtubules and is required for immunity. PLoS Pathog 10(2): e1003952.
  5. Fan, M., Bai, M. Y., Kim, J. G., Wang, T., Oh, E., Chen, L., Park, C. H., Son, S. H., Kim, S. K., Mudgett, M. B. and Wang, Z. Y. (2014). The bHLH transcription factor HBI1 mediates the trade-off between growth and pathogen-associated molecular pattern-triggered immunity in Arabidopsis. Plant Cell 26(2): 828-841.
  6. Magnani, E., de Klein, N., Nam, H. I., Kim, J. G., Pham, K., Fiume, E., Mudgett, M. B. and Rhee, S. Y. (2014). A comprehensive analysis of microProteins reveals their potentially widespread mechanism of transcriptional regulation. Plant Physiol 165(1): 149-159.
  7. Kim, J. G., Stork, W. and Mudgett, M. B. (2013). Xanthomonas type III effector XopD desumoylates tomato transcription factor SlERF4 to suppress ethylene responses and promote pathogen growth. Cell Host Microbe 13(2): 143-154.
  8. Taylor, K. W., Kim, J. G., Su, X. B., Aakre, C. D., Roden, J. A., Adams, C. M. and Mudgett, M. B. (2012). Tomato TFT1 is required for PAMP-triggered immunity and mutations that prevent T3S effector XopN from binding to TFT1 attenuate Xanthomonas virulence. PLoS Pathog 8(6): e1002768.
  9. Sonnewald, S., Priller, J. P., Schuster, J., Glickmann, E., Hajirezaei, M. R., Siebig, S., Mudgett, M. B. and Sonnewald, U. (2012). Regulation of cell wall-bound invertase in pepper leaves by Xanthomonas campestris pv. vesicatoria type three effectors. PLoS One 7(12): e51763.
  10. Kim, J. G., Taylor, K. W. and Mudgett, M. B. (2011). Comparative analysis of the XopD type III secretion (T3S) effector family in plant pathogenic bacteria. Mol Plant Pathol 12(8): 715-730.
  11. Chen, L. Q., Hou, B. H., Lalonde, S., Takanaga, H., Hartung, M. L., Qu, X. Q., Guo, W. J., Kim, J. G., Underwood, W., Chaudhuri, B., Chermak, D., Antony, G., White, F. F., Somerville, S. C., Mudgett, M. B. and Frommer, W. B. (2010). Sugar transporters for intercellular exchange and nutrition of pathogens. Nature 468(7323): 527-532.
  12. Kim, J. G., Li, X., Roden, J. A., Taylor, K. W., Aakre, C. D., Su, B., Lalonde, S., Kirik, A., Chen, Y., Baranage, G., McLane, H., Martin, G. B. and Mudgett, M. B. (2009). Xanthomonas T3S Effector XopN Suppresses PAMP-Triggered Immunity and Interacts with a Tomato Atypical Receptor-Like Kinase and TFT1. Plant Cell 21(4): 1305-1323.
  13. Kirik, A. and Mudgett, M. B. (2009). SOBER1 phospholipase activity suppresses phosphatidic acid accumulation and plant immunity in response to bacterial effector AvrBsT. Proc Natl Acad Sci U S A 106(48): 20532-20537.
  14. Kim, J. G., Taylor, K. W., Hotson, A., Keegan, M., Schmelz, E. A. and Mudgett, M. B. (2008). XopD SUMO protease affects host transcription, promotes pathogen growth, and delays symptom development in xanthomonas-infected tomato leaves. Plant Cell 20(7): 1915-1929.
  15. Cunnac, S., Wilson, A., Nuwer, J., Kirik, A., Baranage, G. and Mudgett, M. B. (2007). A conserved carboxylesterase is a SUPPRESSOR OF AVRBST-ELICITED RESISTANCE in Arabidopsis. Plant Cell 19(2): 688-705.
  16. Doyle, E. A., Lane, A. M., Sides, J. M., Mudgett, M. B. and Monroe, J. D. (2007). An alpha-amylase (At4g25000) in Arabidopsis leaves is secreted and induced by biotic and abiotic stress. Plant Cell Environ 30(4): 388-398.
  17. Swartz, T. E., Tseng, T. S., Frederickson, M. A., Paris, G., Comerci, D. J., Rajashekara, G., Kim, J. G., Mudgett, M. B., Splitter, G. A., Ugalde, R. A., Goldbaum, F. A., Briggs, W. R. and Bogomolni, R. A. (2007). Blue-light-activated histidine kinases: two-component sensors in bacteria. Science 317(5841): 1090-1093.
  18. Mudgett, M. B. (2005). New insights to the function of phytopathogenic bacterial type III effectors in plants. Annu Rev Plant Biol 56: 509-531.
  19. Minsavage, G. V., Mudgett, M. B., Stall, R. E. and Jones, J. B. (2004). Importance of opgHXcv of Xanthomonas campestris pv. vesicatoria in host-parasite interactions. Mol Plant Microbe Interact 17(2): 152-161.
  20. Roden, J., Eardley, L., Hotson, A., Cao, Y. and Mudgett, M. B. (2004). Characterization of the Xanthomonas AvrXv4 effector, a SUMO protease translocated into plant cells. Mol Plant Microbe Interact 17(6): 633-643.
  21. Hotson, A. and Mudgett, M. B. (2004). Cysteine proteases in phytopathogenic bacteria: identification of plant targets and activation of innate immunity. Curr Opin Plant Biol 7(4): 384-390.
  22. Roden, J. A., Belt, B., Ross, J. B., Tachibana, T., Vargas, J. and Mudgett, M. B. (2004). A genetic screen to isolate type III effectors translocated into pepper cells during Xanthomonas infection. Proc Natl Acad Sci U S A 101(47): 16624-16629.
  23. Hotson, A., Chosed, R., Shu, H., Orth, K. and Mudgett, M. B. (2003). Xanthomonas type III effector XopD targets SUMO-conjugated proteins in planta. Mol Microbiol 50(2): 377-389.
  24. Axtell, M. J., McNellis, T. W., Mudgett, M. B., Hsu, C. S. and Staskawicz, B. J. (2001). Mutational analysis of the Arabidopsis RPS2 disease resistance gene and the corresponding pseudomonas syringae avrRpt2 avirulence gene. Mol Plant Microbe Interact 14(2): 181-188.
  25. Staskawicz, B. J., Mudgett, M. B., Dangl, J. L. and Galan, J. E. (2001). Common and contrasting themes of plant and animal diseases. Science 292(5525): 2285-2289.
  26. Orth, K., Xu, Z., Mudgett, M. B., Bao, Z. Q., Palmer, L. E., Bliska, J. B., Mangel, W. F., Staskawicz, B. and Dixon, J. E. (2000). Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. Science 290(5496): 1594-1597.

Non-peer reviewed publications

  1. Mudgett, M. B., Wilson, A., Cunnac, S., Nuwer, J. and Barange, G. (2005). BST is a novel Arabidopsis defense gene that recognizes the Xanthomonas Type III Effector AvrBsT in Plants and limits Pathogen growth. In: Sanchez, F., Quinto, I., Lopez-Lara, M. and Geiger, O. (eds). Merida, Vol. 5, 364-370.
  2. Roden, J. and Mudgett, M. B. (2003). What type III effector proteins is Xanthomonas injecting into a plant cell during pathogenesis? In: Tikhonovick, I., Lugtenberg, B. and Provorov, N. (eds). Biology of Plant-Microbe Interactions. St. Petersburg, Vol. 4, 142-145.
  3. Hotson, A., Chosed, R., Orth, K. and Mudgett, M. B. (2003). Plant targets for Xanthomonas campestris type III cysteine protease effectors. In: Tikhonovick, I., Lugtenberg, B. and Provorov, N. (eds). Biology of Plant-Microbe Interactions. St. Petersburg, Vol. 4, 127-131.

Book chapters

  1. Mudgett, M.B. and Kim, J. G. (2013). XopD Peptidase. In: Rawlings, N. D. and Guy S. Salvesen, G. S. (eds). Handbook of Proteolytic Enzymes. Academic Press, 2382-2385.
  2. Mudgett, M. B. and Kim, J. G. (2012). Host targets of bacterial effectors. In: Strasburger’s plant sciences. Springer.
Protocols by Mary Beth Mudgett
  1. Quantification of Ethylene Production in Tomato Leaves Infected by Xanthomonas euvesicatoria