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Nadr M. Jomha

Education

Ph.D. in Experimental Surgery, University of Alberta, 2003

Current position

Professor, Department of Surgery, University of Alberta, Staff Orthopaedic Surgeon
Director of Orthopaedic Research (2015-present)

Publications (past 10 years)

  1. Pedersen, M. E., DaCambra, M. P., Jibri, Z., Dhillon, S., Jen, H. and Jomha, N. M. (2015). Acute Osteochondral Fractures in the Lower Extremities - Approach to Identification and Treatment. Open Orthop J 9: 463-474.
  2. Bornes, T. D.*, Jomha, N. M., Mulet-Sierra, A. and Adesida, A. B. (2015). Hypoxic culture of bone marrow-derived mesenchymal stromal stem cells differentially enhances in vitro chondrogenesis within cell-seeded collagen and hyaluronic acid porous scaffolds. Stem Cell Res Ther 6: 84.
  3. Alhoukail, A.*, Panu, A., Olson, J. and Jomha, N. M. (2015). Intra-articular peroneal nerve incarceration following multi-ligament knee injury. Knee Surg Sports Traumatol Arthrosc 23(10): 3044-3048.
  4. Yu, H.*, Adesida, A. B. and Jomha, N. M. (2015). Meniscus repair using mesenchymal stem cells - a comprehensive review. Stem Cell Res Ther 6: 86.
  5. Bornes, T. D.*, Adesida, A. B. and Jomha, N. M. (2014). Mesenchymal stem cells in the treatment of traumatic articular cartilage defects: a comprehensive review. Arthritis Res Ther 16(5): 432.
  6. C, L. O.*, M, M. and N, M. J. (2014). Controversies in the management of open fractures. Open Orthop J 8: 178-184.
  7. Islam, K., Dobbe, A., Duke, K., El-Rich, M., Dhillon, S., Adeeb, S. and Jomha, N. M. (2014). Three-dimensional geometric analysis of the talus for designing talar prosthetics. Proc Inst Mech Eng H 228(4): 371-378.
  8. Islam, K., Dobbe, A.*, Komeili, A., Duke, K., El-Rich, M., Dhillon, S., Adeeb, S. and Jomha, N. M. (2014). Symmetry analysis of talus bone: A Geometric morphometric approach. Bone Joint Res 3(5): 139-145.
  9. Fahmy, M. D.*, Almansoori, K. A.*, Laouar, L., Prasad, V., McGann, L. E., Elliott, J. A. and Jomha, N. M. (2014). Dose-injury relationships for cryoprotective agent injury to human chondrocytes. Cryobiology 68(1): 50-56.
  10. Croutze, R.*, Jomha, N., Uludag, H. and Adesida, A. (2013). Matrix forming characteristics of inner and outer human meniscus cells on 3D collagen scaffolds under normal and low oxygen tensions. BMC Musculoskelet Disord 14: 353.
  11. Matthies, N. F., Mulet-Sierra, A., Jomha, N. M. and Adesida, A. B. (2013). Matrix formation is enhanced in co-cultures of human meniscus cells with bone marrow stromal cells. J Tissue Eng Regen Med 7(12): 965-973.
  12. Chowdhury, A., Bezuidenhout, L. W.*, Mulet-Sierra, A., Jomha, N. M. and Adesida, A. B. (2013). Effect of interleukin-1beta treatment on co-cultures of human meniscus cells and bone marrow mesenchymal stromal cells. BMC Musculoskelet Disord 14: 216.
  13. Abazari, A., Jomha, N. M., Elliott, J. A. and McGann, L. E. (2013). Cryopreservation of articular cartilage. Cryobiology 66(3): 201-209.
  14. Yu, H.*, Al-Abbasi, K. K.*, Elliott, J. A., McGann, L. E. and Jomha, N. M. (2013). Clinical efflux of cryoprotective agents from vitrified human articular cartilage. Cryobiology 66(2): 121-125.
  15. Saliken, D. J.*, Mulet-Sierra, A., Jomha, N. M. and Adesida, A. B. (2012). Decreased hypertrophic differentiation accompanies enhanced matrix formation in co-cultures of outer meniscus cells with bone marrow mesenchymal stromal cells. Arthritis Res Ther 14(3): R153.
  16. Jomha, N. M., Elliott, J. A., Law, G. K., Maghdoori, B.*, Forbes, J. F., Abazari, A., Adesida, A. B., Laouar, L., Zhou, X. and McGann, L. E. (2012). Vitrification of intact human articular cartilage. Biomaterials 33(26): 6061-6068.
  17. Adesida, A. B., Mulet-Sierra, A., Laouar, L. and Jomha, N. M. (2012). Oxygen tension is a determinant of the matrix-forming phenotype of cultured human meniscal fibrochondrocytes. PLoS One 7(6): e39339.
  18. Yeung, T. Y., Seeberger, K. L., Kin, T., Adesida, A., Jomha, N., Shapiro, A. M. and Korbutt, G. S. (2012). Human mesenchymal stem cells protect human islets from pro-inflammatory cytokines. PLoS One 7(5): e38189.
  19. Adesida, A. B., Mulet-Sierra, A. and Jomha, N. M. (2012). Hypoxia mediated isolation and expansion enhances the chondrogenic capacity of bone marrow mesenchymal stromal cells. Stem Cell Res Ther 3(2): 9.
  20. Almansoori, K. A.*, Prasad, V., Forbes, J. F., Law, G. K., McGann, L. E., Elliott, J. A. and Jomha, N. M. (2012). Cryoprotective agent toxicity interactions in human articular chondrocytes. Cryobiology 64(3): 185-191.
  21. Mostafa, N. Z., Fitzsimmons, R., Major, P. W., Adesida, A., Jomha, N., Jiang, H. and Uludag, H. (2012). Osteogenic differentiation of human mesenchymal stem cells cultured with dexamethasone, vitamin D3, basic fibroblast growth factor, and bone morphogenetic protein-2. Connect Tissue Res 53(2): 117-131.
  22. Jomha, N. M., Weiss, A. D.*, Fraser Forbes, J., Law, G. K., Elliott, J. A. and McGann, L. E. (2010). Cryoprotectant agent toxicity in porcine articular chondrocytes. Cryobiology 61(3): 297-302.
  23. El-Bialy, T., Uludag, H., Jomha, N. and Badylak, S. F. (2010). In vivo ultrasound-assisted tissue-engineered mandibular condyle: a pilot study in rabbits. Tissue Eng Part C Methods 16(6): 1315-1323.
  24. Weiss, A. D.*, Forbes, J. F., Scheuerman, A., Law, G. K., Elliott, J. A., McGann, L. E. and Jomha, N. M. (2010). Statistical prediction of the vitrifiability and glass stability of multi-component cryoprotective agent solutions. Cryobiology 61(1): 123-127.
  25. Bostick, G. P., Jomha, N. M., Suchak, A. A. and Beaupre, L. A. (2010). Factors associated with calf muscle endurance recovery 1 year after achilles tendon rupture repair. J Orthop Sports Phys Ther 40(6): 345-351.
  26. Barley, R. D., Adesida, A. B., Bagnall, K. M. and Jomha, N. M. (2010). Immunohistochemical characterization of reparative tissue present in human osteoarthritic tissue. Virchows Arch 456(5): 561-569.
  27. Secretan, C., Bagnall, K. M. and Jomha, N. M. (2010). Effects of introducing cultured human chondrocytes into a human articular cartilage explant model. Cell Tissue Res 339(2): 421-427.
  28. Barley, R. D., Bagnall, K. M.* and Jomha, N. M. (2010). Histological scoring of articular cartilage alone provides an incomplete picture of osteoarthritic disease progression. Histol Histopathol 25(3): 291-297.
  29. Abazari, A., Elliott, J. A., Law, G. K., McGann, L. E. and Jomha, N. M. (2009). A biomechanical triphasic approach to the transport of nondilute solutions in articular cartilage. Biophys J 97(12): 3054-3064.
  30. Jomha, N. M., Law, G. K., Abazari, A., Rekieh, K., Elliott, J. A. and McGann, L. E. (2009). Permeation of several cryoprotectant agents into porcine articular cartilage. Cryobiology 58(1): 110-114.
  31. El-Bialy, T., Uludag, H., Mousa, W., Lalh, S., Jomha, N. and Badylak, S. (2008). In-vivo ultrasound assisted tissue engineered articular condyle. Canadian Acoustics 36(3): 42-43.
  32. Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures, I., Bhandari, M., Guyatt, G., Tornetta, P., 3rd, Schemitsch, E. H., Swiontkowski, M., Sanders, D. and Walter, S. D. (2008). Randomized trial of reamed and unreamed intramedullary nailing of tibial shaft fractures. J Bone Joint Surg Am 90(12): 2567-2578.
  33. Suchak, A. A.*, Bostick, G. P., Beaupre, L. A., Durand, D. C. and Jomha, N. M. (2008). The influence of early weight-bearing compared with non-weight-bearing after surgical repair of the Achilles tendon. J Bone Joint Surg Am 90(9): 1876-1883.
  34. Sharma, R.*, Law, G. K., Rekieh, K.*, Abazari, A., Elliott, J. A., McGann, L. E. and Jomha, N. M. (2007). A novel method to measure cryoprotectant permeation into intact articular cartilage. Cryobiology 54(2): 196-203.
  35. Elmoazzen, H. Y., Poovadan, A., Law, G. K., Elliott, J. A., McGann, L. E. and Jomha, N. M. (2007). Dimethyl sulfoxide toxicity kinetics in intact articular cartilage. Cell Tissue Bank 8(2): 125-133.
  36. Jahns, M. E., Lou, E., Durdle, N. G., Bagnall, K., Raso, V. J., Cinats, D., Barley, R. D., Cinats, J. and Jomha, N. M. (2007). The effect of pulsed electromagnetic fields on chondrocyte morphology. Med Biol Eng Comput 45(10): 917-925.
  37.  Laouar, L., Fishbein, K., McGann, L. E., Horton, W. E., Spencer, R. G. and Jomha, N. M. (2007). Cryopreservation of porcine articular cartilage: MRI and biochemical results after different freezing protocols. Cryobiology 54(1): 36-43.
  38. Jomha, N. M., Elliott, J. A., Law, G. K. and McGann, L. E. (2007). Evaluation of chondrocyte survival in situ using WST-1 and membrane integrity stains. Cell Tissue Bank 8(3): 179-186.
  39. Sharma, R.*, Jomha, N. M. and Otto, D. D. (2006). Recurrent dislocation of the tibialis posterior tendon. Am J Sports Med 34(11): 1852-1854.
  40. Jiang, H., Secretan, C.*, Gao, T., Bagnall, K., Korbutt, G., Lakey, J. and Jomha, N. M. (2006). The development of osteoblasts from stem cells to supplement fusion of the spine during surgery for AIS. Stud Health Technol Inform 123: 467-472.
  41. Suchak, A. A.*, Spooner, C., Reid, D. C. and Jomha, N. M. (2006). Postoperative rehabilitation protocols for Achilles tendon ruptures: a meta-analysis. Clin Orthop Relat Res 445: 216-221.
  42. Jomha, N. M., Law, G. K. and McGann, L. E. (2006). Storage of porcine articular cartilage at high subzero temperatures. Cell Tissue Bank 7(1): 55-60.

Protocols by Nadr M. Jomha
  1. Porous Scaffold Seeding and Chondrogenic Differentiation of BMSC-seeded Scaffolds