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Sebastien  Benzekry

Sebastien Benzekry


Doctorate of applied mathematics, LATP and Laboratoire de Pharmacocinetique et Toxicocinetique, Marseille, 2011

Current position

Junior Researcher (CR1) at Inria Bordeaux, team MONC


  1. Benzekry, S., Tracz, A., Mastri, M., Corbelli, R., Barbolosi, D. and Ebos, J. M. (2015). Modeling spontaneous metastasis following surgery: an in vivo-in silico approach. Cancer Res.
  2. Benzekry, S.*, Pasquier, E.*, Barbolosi, D., Lacarelle, B., Barlesi, F., Andre, N. and Ciccolini, J. (2015). Metronomic reloaded: Theoretical models bringing chemotherapy into the era of precision medicine. Semin Cancer Biol.
  3. Ciccolini, J., Benzekry, S., Lacarelle, B., Barbolosi, D. and Barlesi, F. (2015). Improving efficacy of the combination between antiangiogenic and chemotherapy: Time for mathematical modeling support. Proc Natl Acad Sci U S A 112(27): E3453.
  4. Benzekry, S., Tuszynski, J. A., Rietman, E. A. and Lakka Klement, G. (2015). Design principles for cancer therapy guided by changes in complexity of protein-protein interaction networks. Biol Direct 10: 32.
  5. Beheshti, A., Benzekry, S., McDonald, J. T., Ma, L., Peluso, M., Hahnfeldt, P. and Hlatky, L. (2015). Host age is a systemic regulator of gene expression impacting cancer progression. Cancer Res 75(6): 1134-1143.
  6. Baratchart, E., Benzekry, S.*, Bikfalvi, A.*, Colin, T.*, Cooley, L. S., Pineau, R., Ribot, E., Saut, O. and Souleyreau, W. (2015). Computational modelling of metastasis development in renal cell carcinoma. PloS Comput Biol.
  7. Benzekry, S., Beheshti, A., Hahnfeldt, P. and Hlatky, L. (2015). Capturing the driving role of tumor-host crosstalk in a dynamical model of tumor growth. Bio-protocol 5(21): e1644.
  8. Benzekry, S., Lamont, C., Beheshti, A., Tracz, A., Ebos, J. M., Hlatky, L. and Hahnfeldt, P. (2014). Classical mathematical models for description and prediction of experimental tumor growth. PLoS Comput Biol 10(8): e1003800.
  9. Benzekry, S., Gandolfi, A. and Hahnfeldt, P. (2014). Global dormancy of metastases due to systemic inhibition of angiogenesis. PLoS One 9(1): e84249.
  10. Barbolosi, D., Benabdallah, A., Benzekry, S., Ciccolini, J., Faivre, C., Hubert, F., Verga, F. and You, B. (2014). A Mathematical Model for Growing Metastases on Oncologists's Service. In Computational Surgery and Dual Training, Springer New York 331-338.
  11. Benzekry, S. and Hahnfeldt, P. (2013). Maximum tolerated dose versus metronomic scheduling in the treatment of metastatic cancers. J Theor Biol 335: 235-244.
  12. Lignet, F., Benzekry, S., Wilson, S., Billy, F., Saut, O., Tod, M., You, B., Adda Berkane, A., Kassour, S., Wei, M. X., Grenier, E. and Ribba, B. (2013). Theoretical investigation of the efficacy of antiangiogenic drugs combined to chemotherapy in xenografted mice. J Theor Biol 320: 86-99.
  13. Benzekry, S. (2012). Passing to the limit 2D-1D in a model for metastatic growth. J Biol Dyn 6 Suppl 1: 19-30.
  14. Benzekry, S., Andre, N., Benabdallah, A., Ciccolini, J., Faivre, C., Hubert, F., Barbolosi, D. (2012). Modeling the impact of anticancer agents on metastatic spreading. Mathematical Modeling of Natural Phenomena 7 (1): 306-336.
  15. Benzekry, S., Chapuisat, G., Ciccolini, J., Erlinger, A. and Hubert, F. (2012). A new mathematical model for optimizing the combination between antiangiogenic and cytotoxic drugs in oncology. Comptes Rendus de l'Academie des Sciences - Mathematiques 350: 23-28.
  16. Benzekry, S. (2012). Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers. M2AN 46 (2): 207-237.
  17. Benzekry, S. (2012). Mathematical analysis of a two-dimensional population model of metastatic growth including angiogenesis. J Evol Equ 11(1): 187-213.
Protocols by Sebastien Benzekry
  1. Capturing the Driving Role of Tumor-Host Crosstalk in a Dynamical Model of Tumor Growth