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Baruch Minke

Education

Ph.D. in Physiology and Biophysics, Faculty of Science of the Hebrew University, Jerusalem, Israel

Current position

Professor of Physiology, Department of Medical Neurobiology, Faculty of Medicine, Hebrew University, Jerusalem, Israel

Publications (since 2005)

  1. Weiss, S. and Minke, B. (2015). A new genetic model for calcium induced autophagy and ER-stress in Drosophila photoreceptor cells. Channels (Austin) 9(1): 14-20.
  2. Kohn, E., Katz, B., Yasin, B., Peters, M., Rhodes, E., Zaguri, R., Weiss, S. and Minke, B. (2015). Functional cooperation between the IP3 receptor and phospholipase C secures the high sensitivity to light of Drosophila photoreceptors in vivo. J Neurosci 35(6): 2530-2546.
  3. Katz, B., Oberacker, T., Richter, D., Tzadok, H., Peters, M., Minke, B. and Huber, A. (2013). Drosophila TRP and TRPL are assembled as homomultimeric channels in vivo. J Cell Sci 126(Pt 14): 3121-3133.
  4. Lev, S., Katz, B., Tzarfaty, V. and Minke, B. (2012). Signal-dependent hydrolysis of phosphatidylinositol 4,5-bisphosphate without activation of phospholipase C: implications on gating of Drosophila TRPL (transient receptor potential-like) channel. J Biol Chem 287(2): 1436-1447.
  5. Katz, B. and Minke, B. (2012). Phospholipase C-mediated suppression of dark noise enables single-photon detection in Drosophila photoreceptors. J Neurosci 32(8): 2722-2733.
  6. Lev, S., Katz, B. and Minke, B. (2012). The activity of the TRP-like channel depends on its expression system. Channels (Austin) 6(2): 86-93.
  7. Minke, B. (2012). The history of the prolonged depolarizing afterpotential (PDA) and its role in genetic dissection of Drosophila phototransduction. J Neurogenet 26(2): 106-117.
  8. Parnas, M., Peters, M. and Minke, B. (2012). In: Edward H. Egelman, (ed). Biophysics of TRP channels. Comprehensive biophysics. Academic Press, 68-107.
  9. Weiss, S., Kohn, E., Dadon, D., Katz, B., Peters, M., Lebendiker, M., Kosloff, M., Colley, N. J. and Minke, B. (2012). Compartmentalization and Ca2+ buffering are essential for prevention of light-induced retinal degeneration. J Neurosci 32(42): 14696-14708.
  10. Peters, M., Trembovler, V., Alexandrovich, A., Parnas, M., Birnbaumer, L., Minke, B. and Shohami, E. (2012). Carvacrol together with TRPC1 elimination improve functional recovery after traumatic brain injury in mice. J Neurotrauma 29(18): 2831-2834.
  11. Szallasi, A. (2011). TRP channels in health and disease: implications for diagnosis and therapy, Nova Science Publishers.
  12. Lev, S. and Minke, B. (2010). Constitutive activity of TRP channels methods for measuring the activity and its outcome. Methods Enzymol 484: 591-612.
  13. Minke, B. (2010). The history of the Drosophila TRP channel: the birth of a new channel superfamily. J Neurogenet 24(4): 216-233.
  14. Minke, B. and Peters, M. (2011). Cell biology. Rhodopsin as thermosensor? Science 331(6022): 1272-1273.
  15. Richter, D., Katz, B., Oberacker, T., Tzarfaty, V., Belusic, G., Minke, B. and Huber, A. (2011). Translocation of the Drosophila transient receptor potential-like (TRPL) channel requires both the N- and C-terminal regions together with sustained Ca2+ entry. J Biol Chem 286(39): 34234-34243.
  16. Kohn, E. and Minke, B. (2011). Methods for Studying Drosophila TRP Channels. In: Zhu, M. X. (ed). TRP channels. Boca Raton (FL): CRC Press, Chapter 20.
  17. Katz, B. and Minke, B. (2011). Genetic Dissection of Invertebrate Phototransduction. The Retina and Its Disorders: 240.
  18. Lev, S., Zeevi, D. A., Frumkin, A., Offen-Glasner, V., Bach, G. and Minke, B. (2010). Constitutive activity of the human TRPML2 channel induces cell degeneration. J Biol Chem 285(4): 2771-2782.
  19. Dadon, D. and Minke, B. (2010). Cellular functions of transient receptor potential channels. Int J Biochem Cell Biol 42(9): 1430-1445.
  20. Zeevi, D. A., Lev, S., Frumkin, A., Minke, B. and Bach, G. (2010). Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy. J Cell Sci 123(Pt 18): 3112-3124.
  21. Parnas, M., Katz, B., Lev, S., Tzarfaty, V., Dadon, D., Gordon-Shaag, A., Metzner, H., Yaka, R. and Minke, B. (2009). Membrane lipid modulations remove divalent open channel block from TRP-like and NMDA channels. J Neurosci 29(8): 2371-2383. (covered by the "EDITORS' CHOICE" section of the web publication of Science, Sci.Signal, 2(60) p.ec80)
  22. Frechter, S., Elia, N., Tzarfaty, V., Selinger, Z. and Minke, B. (2007). Translocation of Gq alpha mediates long-term adaptation in Drosophila photoreceptors. J Neurosci 27(21): 5571-5583.
  23. Minke, B. and Parnas, M. (2006). Insights on TRP channels from in vivo studies in Drosophila. Annu Rev Physiol 68: 649-684.
  24. Chorna-Ornan, I., Tzarfaty, V., Ankri-Eliahoo, G., Joel-Almagor, T., Meyer, N. E., Huber, A., Payre, F. and Minke, B. (2005). Light-regulated interaction of Dmoesin with TRP and TRPL channels is required for maintenance of photoreceptors. J Cell Biol 171(1): 143-152.
  25. Elia, N., Frechter, S., Gedi, Y., Minke, B. and Selinger, Z. (2005). Excess of Gbetae over Gqalphae in vivo prevents dark, spontaneous activity of Drosophila photoreceptors. J Cell Biol 171(3): 517-526. (Covered in the News Section)
Protocols by Baruch Minke
  1. Electroretinogram (ERG) Recordings from Drosophila