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Isabelle Ernens


Ph.D. in Agronomical Sciences and Biological Engineering, Department of Nutrition Biochemistry, University of Louvain-la-Neuve, Be, 2001

Current position

Research Scientist in the Cardiovascular Research Unit, Luxembourg Institute of Health, Lu


  1. Ernens, I., Bousquenaud, M., Lenoir, B., Devaux, Y. and Wagner, D. R. (2015). Adenosine stimulates angiogenesis by up-regulating production of thrombospondin-1 by macrophages. J Leukoc Biol 97(1): 9-18.
  2. Haas, B., Leonard, F., Ernens, I., Rodius, S., Vausort, M., Rolland-Turner, M., Devaux, Y. and Wagner, D. R. (2011). Adenosine reduces cell surface expression of toll-like receptor 4 and inflammation in response to lipopolysaccharide and matrix products. J Cardiovasc Transl Res 4(6): 790-800.
  3. Leonard, F., Devaux, Y., Vausort, M., Ernens, I., Rolland-Turner, M. and Wagner, D. R. (2011). Adenosine modifies the balance between membrane and soluble forms of Flt-1. J Leukoc Biol 90(1): 199-204.
  4. Ernens, I., Leonard, F., Vausort, M., Rolland-Turner, M., Devaux, Y. and Wagner, D. R. (2010). Adenosine up-regulates vascular endothelial growth factor in human macrophages. Biochem Biophys Res Commun 392(3): 351-356.
  5. Velot, E., Haas, B., Leonard, F., Ernens, I., Rolland-Turner, M., Schwartz, C., Longrois, D., Devaux, Y. and Wagner, D. R. (2008). Activation of the adenosine-A3 receptor stimulates matrix metalloproteinase-9 secretion by macrophages. Cardiovasc Res 80(2): 246-254.
  6. Ernens, I., Clegg, R., Schneider, Y. J. and Larondelle, Y. (2007). Short communication: Ability of cultured mammary epithelial cells in a bicameral system to secrete milk fat. J Dairy Sci 90(2): 677-681.
  7. Ernens, I., Rouy, D., Velot, E., Devaux, Y. and Wagner, D. R. (2006). Adenosine inhibits matrix metalloproteinase-9 secretion by neutrophils: implication of A2a receptor and cAMP/PKA/Ca2+ pathway. Circ Res 99(6): 590-597.
  8. Wagner, D. R., Delagardelle, C., Ernens, I., Rouy, D., Vaillant, M. and Beissel, J. (2006). Matrix metalloproteinase-9 is a marker of heart failure after acute myocardial infarction. J Card Fail 12(1): 66-72.
  9. Ernens, I., Goodfellow, S. J., Innes, F., Kenneth, N. S., Derblay, L. E., White, R. J. and Scott, P. H. (2006). Hypoxic stress suppresses RNA polymerase III recruitment and tRNA gene transcription in cardiomyocytes. Nucleic Acids Res 34(1): 286-294.
  10. Rouy, D., Ernens, I., Jeanty, C. and Wagner, D. R. (2005). Plasma storage at -80 degrees C does not protect matrix metalloproteinase-9 from degradation. Anal Biochem 338(2): 294-298.
Protocols by Isabelle Ernens
  1. Rat Aortic Ring Model to Assay Angiogenesis ex vivo