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Jidnyasa Ingale


PhD in Biochemistry and Bio-Organic Chemistry, The University Of Georgia, Athens, GA, USA, 2009

Current position

Research Associate (Prof. Richard Wyatt), The Scripps Research Institute, La Jolla, CA, USA (2013- present)


  1. Phad, G. E., Bernat, N. V., Feng, Y., Ingale, J., Murillo, P. A. M., O’Dell, S., Li, Y., Mascola, J. R., Sundling, C. and Wyatt, R. T. (2015). Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization. The Journal of Immunology: 1500122.
  2. Feng, Y., Jiang, H., Ingale, J., McKee, K., Mascola, J. and Wyatt, R. (2014). Antigenicity and Immunogenicity of Disulfide-stabilized HIV-1 Envelope Glycoprotein Oligomers. AIDS research and human retroviruses 30(S1): A84-A85.
  3. Ingale, J., Tran, K., Kong, L., Dey, B., McKee, K., Schief, W., Kwong, P. D., Mascola, J. R. and Wyatt, R. T. (2014). Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies. J Virol 88(24): 14002-14016.
  4. Gaekwad, J., Reeves, J., Wolfert, M. A. and Boons, G. J. (2010). Modulation of TLR4 activation with different synthetic lipid A derivatives. Journal of Biological Chemistry 285 (38): 29375-86.
  5. Zhang, Y., Gaekwad, J., Wolfert, M. A. and Boons, G.-J. (2008). Synthetic tetra-acylated derivatives of lipid A from Porphyromonas gingivalis are antagonists of human TLR4. Organic & biomolecular chemistry 6(18): 3371-3381.
  6. Zhang, Y., Gaekwad, J., Wolfert, M. A. and Boons, G. J. (2008). Innate immune responses of synthetic lipid A derivatives of Neisseria meningitidis. Chemistry-A European Journal 14(2): 558-569.
  7. Ingale, S., Wolfert, M. A., Gaekwad, J., Buskas, T. and Boons, G.-J. (2007). Robust immune responses elicited by a fully synthetic three-component vaccine. Nature chemical biology 3(10): 663-667.
  8. Zhang, Y., Gaekwad, J., Wolfert, M. A. and Boons, G.-J. (2007). Modulation of innate immune responses with synthetic lipid A derivatives. Journal of the American Chemical Society 129(16): 5200-5216.
Protocols by Jidnyasa Ingale
  1. Coupling of HIV-1 gp120-derived Core Protein to Paramagnetic Beads and Adsorption Assays
  2. Kinetic Analysis of Monoclonal Antibody Binding to HIV-1 gp120-derived Hyperglycosylated Cores