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Matthew T Tierney

Matthew T Tierney


M.A. in Exercise Physiology, University of Texas at Austin, 2009

Current position

Graduate Student, Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery InstituteLa, Jolla, USA


  1. Kang, Y., Tierney, M., Ong, E., Zhang, L., Piermarocchi, C., Sacco, A. and Paternostro, G. (2015). Combinations of kinase inhibitors protecting myoblasts against hypoxia. PLoS One 10(6): e0126718.
  2. Tierney, M. T.*, Aydogdu, T.*, Sala, D., Malecova, B., Gatto, S., Puri, P. L., Latella, L. and Sacco, A. (2014). STAT3 signaling controls satellite cell expansion and skeletal muscle repair. Nat Med 20(10): 1182-1186.
  3. Chakkalakal, J. V., Christensen, J., Xiang, W., Tierney, M. T., Boscolo, F. S., Sacco, A. and Brack, A. S. (2014). Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state. Development 141(8): 1649-1659.
  4. Gokhin, D. S., Tierney, M. T., Sui, Z., Sacco, A. and Fowler, V. M. (2014). Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle. Mol Biol Cell 25(6): 852-865.
  5. Hwang, Y., Suk, S., Lin, S., Tierney, M., Du, B., Seo, T., Mitchell, A., Sacco, A. and Varghese, S. (2013). Directed in vitro myogenesis of human embryonic stem cells and their in vivo engraftment. PLoS One 8(8): e72023.
  6. Mozzetta, C., Consalvi, S., Saccone, V., Tierney, M., Diamantini, A., Mitchell, K. J., Marazzi, G., Borsellino, G., Battistini, L., Sassoon, D., Sacco, A. and Puri, P. L. (2013). Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice. EMBO Mol Med 5(4): 626-639.
  7. Merritt, E. K., Cannon, M. V., Hammers, D. W., Le, L. N., Gokhale, R., Sarathy, A., Song, T. J., Tierney, M. T., Suggs, L. J., Walters, T. J. and Farrar, R. P. (2010). Repair of traumatic skeletal muscle injury with bone-marrow-derived mesenchymal stem cells seeded on extracellular matrix. Tissue Eng Part A 16(9): 2871-2881.
  8. Merritt, E. K., Hammers, D. W., Tierney, M., Suggs, L. J., Walters, T. J. and Farrar, R. P. (2010). Functional assessment of skeletal muscle regeneration utilizing homologous extracellular matrix as scaffolding. Tissue Eng Part A 16(4): 1395-1405.
  9. Tierney, M. T., Lenar, D., Stanforth, P. R., Craig, J. N. and Farrar, R. P. (2010). Prediction of aerobic capacity in firefighters using submaximal treadmill and stairmill protocols. J Strength Cond Res 24(3): 757-764.
Protocols by Matthew T Tierney
  1. FACS-based Satellite Cell Isolation From Mouse Hind Limb Muscles