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This photo is credited to Daniel Hinterramskogler, MFPL

Andreas Bachmair

Education

Ph.D., University of Vienna, Vienna, Austria, 1984

Current position

Associate Professor at the Center for Molecular Biology, Max F. Perutz Laboratories, Dept. of Biochemistry and Cell Biology, University of Vienna, Vienna, Austria

Publications (since 2009)

  1. Potuschak, T. and Bachmair, A. (2015). Seedling germination: Seedlings follow sunshine and fresh air. Curr Biol 25(13): R565-566.
  2. Martens, S. and Bachmair, A. (2015). How cells coordinate waste removal through their major proteolytic pathways. Nat Cell Biol 17(7): 841-842.
  3. Tomanov, K., Zeschmann, A., Hermkes, R., Eifler, K., Ziba, I., Grieco, M., Novatchkova, M., Hofmann, K., Hesse, H. and Bachmair, A. (2014). Arabidopsis PIAL1 and 2 promote SUMO chain formation as E4-type SUMO ligases and are involved in stress responses and sulfur metabolism. Plant Cell 26(11): 4547-4560. 
  4. Khan, M., Rozhon, W., Unterholzner, S. J., Chen, T., Eremina, M., Wurzinger, B., Bachmair, A., Teige, M., Sieberer, T., Isono, E. and Poppenberger, B. (2014). Interplay between phosphorylation and SUMOylation events determines CESTA protein fate in brassinosteroid signalling. Nat Commun 5: 4687.
  5. Gibbs, D. J., Bacardit, J., Bachmair, A. and Holdsworth, M. J. (2014). The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions. Trends Cell Biol 24(10): 603-611.
  6. Villajuana-Bonequi, M., Elrouby, N., Nordstrom, K., Griebel, T., Bachmair, A. and Coupland, G. (2014). Elevated salicylic acid levels conferred by increased expression of ISOCHORISMATE SYNTHASE 1 contribute to hyperaccumulation of SUMO1 conjugates in the Arabidopsis mutant early in short days 4. Plant J 79(2): 206-219.
  7. Tomanov, K., Luschnig, C. and Bachmair, A. (2014). Ubiquitin Lys 63 chains - second-most abundant, but poorly understood in plants. Front Plant Sci 5: 15.
  8. Gibbs, D. J., Md Isa, N., Movahedi, M., Lozano-Juste, J., Mendiondo, G. M., Berckhan, S., Marin-de la Rosa, N., Vicente Conde, J., Sousa Correia, C., Pearce, S. P., Bassel, G. W., Hamali, B., Talloji, P., Tomé, D. F., Coego, A., Beynon, J., Alabadi, D., Bachmair, A., Leon, J., Gray, J. E., Theodoulou, F. L. and Holdsworth, M. J. (2014). Nitric oxide sensing in plants is mediated by proteolytic control of group VII ERF transcription factors. Mol Cell 53(3): 369-379.
  9. Sedlazeck, F. J., Talloji, P., von Haeseler, A. and Bachmair, A. (2013). Benefit-of-doubt (BOD) scoring: a sequencing-based method for SNP candidate assessment from high to medium read number data sets. Genomics 101(3): 204-209.
  10. Tomanov, K., Hardtke, C., Budhiraja, R., Hermkes, R., Coupland, G. and Bachmair, A. (2013). Small ubiquitin-like modifier conjugating enzyme with active site mutation acts as dominant negative inhibitor of SUMO conjugation in arabidopsis(F). J Integr Plant Biol 55(1): 75-82. 
  11. Leitner, J., Petrášek, J., Tomanov, K., Retzer, K., Pařezová, M., Korbei, B., Bachmair, A., Zažímalová, E. and Luschnig, C. (2012). Lysine63-linked ubiquitylation of PIN2 auxin carrier protein governs hormonally controlled adaptation of Arabidopsis root growth. Proc Natl Acad Sci U S A 109(21): 8322-8327.
  12. Novatchkova, M., Tomanov, K., Hofmann, K., Stuible, H. P. and Bachmair, A. (2012). Update on sumoylation: defining core components of the plant SUMO conjugation system by phylogenetic comparison. New Phytol 195(1): 23-31.
  13. Tramontano, A., Donath, A., Bernhart, S. H., Reiche, K., Böhmdorfer, G., Stadler, P. F. and Bachmair, A. (2011). Deletion analysis of the 3' long terminal repeat sequence of plant retrotransposon Tto1 identifies 125 base pairs redundancy as sufficient for first strand transfer. Virology 412(1): 75-82.
  14. Hermkes, R., Fu, Y. F., Nurrenberg, K., Budhiraja, R., Schmelzer, E., Elrouby, N., Dohmen, R. J., Bachmair, A. and Coupland, G. (2011). Distinct roles for Arabidopsis SUMO protease ESD4 and its closest homolog ELS1. Planta 233(1): 63-73.
  15. Böhmdorfer, G., Tramontano, A., Luxa, K. and Bachmair, A. (2010). A synthetic biology approach allows inducible retrotransposition in whole plants. Syst Synth Biol 4(2): 133-138.
  16. Holman, T. J., Jones, P. D., Russell, L., Medhurst, A., Úbeda Tomás, S., Talloji, P., Marquez, J., Schmuths, H., Tung, S. A., Taylor, I., Footitt, S., Bachmair, A., Theodoulou, F. L. and Holdsworth, M. J. (2009). The N-end rule pathway promotes seed germination and establishment through removal of ABA sensitivity in Arabidopsis. Proc Natl Acad Sci U S A 106(11): 4549-4554.
  17. Budhiraja, R., Hermkes, R., Müller, S., Schmidt, J., Colby, T., Panigrahi, K., Coupland, G. and Bachmair, A. (2009). Substrates related to chromatin and to RNA-dependent processes are modified by Arabidopsis SUMO isoforms that differ in a conserved residue with influence on desumoylation. Plant Physiol 149(3): 1529-1540.
  18. Gu, X., Jiang, D., Wang, Y., Bachmair, A. and He, Y. (2009). Repression of the floral transition via histone H2B monoubiquitination. Plant J 57(3): 522-533.

Protocols by Andreas Bachmair
  1. Expression and Purification of the Arabidopsis E4 SUMO Ligases PIAL1 and PIAL2