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Trevor  Lithgow

Trevor Lithgow


Ph.D. in Biochemistry, La Trobe University in Melbourne, 1992

Current position

Trevor Lithgow is a Professor in the School of Biomedical Sciences at Monash University and a Fellow of the Australian Academy of Sciences. Professor Lithgow’s lab has expertise in molecular biology, cell biology, microbiology and bioinformatics. Current research projects in the Lithgow lab include the discovery and characterization of protein transport machines in bacteria and mitochondria, understanding the assembly of these and other molecular machines on bacterial cell surfaces, and studying the evolution of bacterial cell surfaces


  1. Dunstan, R. A., Heinz, E., Wijeyewickrema, L. C., Pike, R. N., Purcell, A. W., Evans, T. J., Praszkier, J., Robins-Browne, R. M., Strugnell, R. A., Korotkov, K. V. and Lithgow, T. (2013). Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS. PLoS Pathog 9(1): e1003117.
  2. Hewitt, V. L., Heinz, E., Shingu-Vazquez, M., Qu, Y., Jelicic, B., Lo, T. L., Beilharz, T. H., Dumsday, G., Gabriel, K., Traven, A. and Lithgow, T. (2012). A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways. Proc Natl Acad Sci U S A 109(49): E3358-3366.
  3. Selkrig, J., Mosbahi, K., Webb, C. T., Belousoff, M. J., Perry, A. J., Wells, T. J., Morris, F., Leyton, D. L., Totsika, M., Phan, M. D., Celik, N., Kelly, M., Oates, C., Hartland, E. L., Robins-Browne, R. M., Ramarathinam, S. H., Purcell, A. W., Schembri, M. A., Strugnell, R. A., Henderson, I. R., Walker, D. and Lithgow, T. (2012). Discovery of an archetypal protein transport system in bacterial outer membranes. Nat Struct Mol Biol 19(5): 506-510, S501.
  4. Webb, C. T., Heinz, E. and Lithgow, T. (2012). Evolution of the beta-barrel assembly machinery. Trends Microbiol 20(12): 612-620.
Protocols by Trevor Lithgow
  1. Preparation of Mitochondria from Candida albicans
  2. Candida albicans Mitochondrial Protein Import Assay