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Zena  Werb

Zena Werb


Ph.D. in Cell Biology, Rockefeller University, New York, 1971

Current position

Professor and vice-Chair, Department of Anatomy, University of California, San Francisco

Publications (>450 total full publications)

  1. Casbon, A. J., Reynaud, D., Park, C., Khuc, E., Gan, D. D., Schepers, K., Passegue, E. and Werb, Z. (2015). Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils. Proc Natl Acad Sci U S A 112(6): E566-575.
  2. Plaks, V., Kong, N. and Werb, Z. (2015). The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells? Cell Stem Cell 16(3): 225-238.
  3. Lohela, M., Casbon, A. J., Olow, A., Bonham, L., Branstetter, D., Weng, N., Smith, J. and Werb, Z. (2014). Intravital imaging reveals distinct responses of depleting dynamic tumor-associated macrophage and dendritic cell subpopulations. Proc Natl Acad Sci U S A 111(47): E5086-5095.
  4. Kessenbrock, K., Dijkgraaf, G. J., Lawson, D. A., Littlepage, L. E., Shahi, P., Pieper, U. and Werb, Z. (2013). A role for matrix metalloproteinases in regulating mammary stem cell function via the Wnt signaling pathway. Cell Stem Cell 13(3): 300-313.
  5. Plaks, V., Brenot, A., Lawson, D. A., Linnemann, J. R., Van Kappel, E. C., Wong, K. C., de Sauvage, F., Klein, O. D. and Werb, Z. (2013). Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis. Cell Rep 3(1): 70-78.
  6. Chou, J., Lin, J. H., Brenot, A., Kim, J. W., Provot, S. and Werb, Z. (2013). GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat Cell Biol 15(2): 201-213.
  7. Kessenbrock, K., Plaks, V. and Werb, Z. (2010). Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 141(1): 52-67.
  8. Ewald, A. J., Brenot, A., Duong, M., Chan, B. S. and Werb, Z. (2008). Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev Cell 14(4): 570-581.
  9. Coussens, L. M. and Werb, Z. (2002). Inflammation and cancer. Nature 420(6917): 860-867.
  10. Vu, T. H., Shipley, J. M., Bergers, G., Berger, J. E., Helms, J. A., Hanahan, D., Shapiro, S. D., Senior, R. M. and Werb, Z. (1998). MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 93(3): 411-422.
Protocols by Zena Werb
  1. Animal Models of Corneal Injury
  2. Confocal Imaging of Myeloid Cells in the Corneal Stroma of Live Mice