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Guadalupe Ortiz-Muñoz

Education

Ph.D., Autonoma University of Madrid, 2008

Current position

Postdoctoral researcher, School of Medicine, University of California, San Francisco, San Francisco, USA (2011-current)

Publications

  1. Recio, C., Oguiza, A., Mallavia, B., Lazaro, I., Ortiz-Munoz, G., Lopez-Franco, O., Egido, J. and Gomez-Guerrero, C. (2015). Gene delivery of suppressors of cytokine signaling (SOCS) inhibits inflammation and atherosclerosis development in mice. Basic Res Cardiol 110(2): 8.
  2. Sayah, D. M., Mallavia, B., Liu, F., Ortiz-Munoz, G., Caudrillier, A., DerHovanessian, A., Ross, D. J., Lynch, J. P., 3rd, Saggar, R., Ardehali, A., Lung Transplant Outcomes Group, I., Ware, L. B., Christie, J. D., Belperio, J. A. and Looney, M. R. (2015). Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med 191(4): 455-463.
  3. Ortiz-Munoz, G., Mallavia, B., Bins, A., Headley, M., Krummel, M. F. and Looney, M. R. (2014). Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice. Blood 124(17): 2625-2634.
  4. Mallavia, B., Oguiza, A., Lopez-Franco, O., Recio, C., Ortiz-Munoz, G., Lazaro, I., Lopez-Parra, V., Egido, J. and Gomez-Guerrero, C. (2013). Gene Deficiency in Activating Fcgamma Receptors Influences the Macrophage Phenotypic Balance and Reduces Atherosclerosis in Mice. PLoS One 8(6): e66754.
  5. Mallavia, B., Recio, C., Oguiza, A., Ortiz-Munoz, G., Lazaro, I., Lopez-Parra, V., Lopez-Franco, O., Schindler, S., Depping, R., Egido, J. and Gomez-Guerrero, C. (2013). Peptide inhibitor of NF-kappaB translocation ameliorates experimental atherosclerosis. Am J Pathol 182(5): 1910-1921.
  6. Lapergue, B., Dang, B. Q., Desilles, J. P., Ortiz-Munoz, G., Delbosc, S., Loyau, S., Louedec, L., Couraud, P. O., Mazighi, M., Michel, J. B., Meilhac, O. and Amarenco, P. (2013). High-density lipoprotein-based therapy reduces the hemorrhagic complications associated with tissue plasminogen activator treatment in experimental stroke. Stroke 44(3): 699-707.
  7. Fernandez-Vizarra, P., Lopez-Franco, O., Mallavia, B., Higuera-Matas, A., Lopez-Parra, V., Ortiz-Munoz, G., Ambrosio, E., Egido, J., Almeida, O. F. and Gomez-Guerrero, C. (2012). Immunoglobulin G Fc receptor deficiency prevents Alzheimer-like pathology and cognitive impairment in mice. Brain 135(Pt 9): 2826-2837.
  8. Lopez-Parra, V., Mallavia, B., Lopez-Franco, O., Ortiz-Munoz, G., Oguiza, A., Recio, C., Blanco, J., Nimmerjahn, F., Egido, J. and Gomez-Guerrero, C. (2012). Fcgamma receptor deficiency attenuates diabetic nephropathy. J Am Soc Nephrol 23(9): 1518-1527.
  9. Ortiz-Munoz, G., Mallavia, B., Lopez-Franco, O., Hernandez-Vargas, P., Egido, J. and Gomez-Guerrero, C. (2012). Renal delivery of adenovirus and antisense oligonucleotides in rats by retrograde renal vein injection. Methods Mol Biol 886: 321-329.
  10. Ortiz-Munoz, G., Lopez-Parra, V., Lopez-Franco, O., Fernandez-Vizarra, P., Mallavia, B., Flores, C., Sanz, A., Blanco, J., Mezzano, S., Ortiz, A., Egido, J. and Gomez-Guerrero, C. (2010). Suppressors of cytokine signaling abrogate diabetic nephropathy. J Am Soc Nephrol 21(5): 763-772.
  11. Ortiz-Munoz, G., Houard, X., Martin-Ventura, J. L., Ishida, B. Y., Loyau, S., Rossignol, P., Moreno, J. A., Kane, J. P., Chalkley, R. J., Burlingame, A. L., Michel, J. B. and Meilhac, O. (2009). HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property. FASEB J 23(9): 3129-3139.
  12. Ortiz-Munoz, G., Martin-Ventura, J. L., Hernandez-Vargas, P., Mallavia, B., Lopez-Parra, V., Lopez-Franco, O., Munoz-Garcia, B., Fernandez-Vizarra, P., Ortega, L., Egido, J. and Gomez-Guerrero, C. (2009). Suppressors of cytokine signaling modulate JAK/STAT-mediated cell responses during atherosclerosis. Arterioscler Thromb Vasc Biol 29(4): 525-531.
  13. Hernandez-Vargas, P., Ortiz-Munoz, G., Lopez-Franco, O., Suzuki, Y., Gallego-Delgado, J., Sanjuan, G., Lazaro, A., Lopez-Parra, V., Ortega, L., Egido, J. and Gomez-Guerrero, C. (2006). Fcgamma receptor deficiency confers protection against atherosclerosis in apolipoprotein E knockout mice. Circ Res 99(11): 1188-1196.
  14. Lopez-Franco, O., Hernandez-Vargas, P., Ortiz-Munoz, G., Sanjuan, G., Suzuki, Y., Ortega, L., Blanco, J., Egido, J. and Gomez-Guerrero, C. (2006). Parthenolide modulates the NF-kappaB-mediated inflammatory responses in experimental atherosclerosis. Arterioscler Thromb Vasc Biol 26(8): 1864-1870.
  15. Gomez-Guerrero, C., Hernandez-Vargas, P., Lopez-Franco, O., Ortiz-Munoz, G. and Egido, J. (2005). Mesangial cells and glomerular inflammation: from the pathogenesis to novel therapeutic approaches. Curr Drug Targets Inflamm Allergy 4(3): 341-351.
  16. Hernandez-Vargas, P., Lopez-Franco, O., Sanjuan, G., Ruperez, M., Ortiz-Munoz, G., Suzuki, Y., Aguado-Roncero, P., Perez-Tejerizo, G., Blanco, J., Egido, J., Ruiz-Ortega, M. and Gomez-Guerrero, C. (2005). Suppressors of cytokine signaling regulate angiotensin II-activated Janus kinase-signal transducers and activators of transcription pathway in renal cells. J Am Soc Nephrol 16(6): 1673-1683.
  17. Gomez-Guerrero, C., Lopez-Franco, O., Sanjuan, G., Hernandez-Vargas, P., Suzuki, Y., Ortiz-Munoz, G., Blanco, J. and Egido, J. (2004). Suppressors of cytokine signaling regulate Fc receptor signaling and cell activation during immune renal injury. J Immunol 172(11): 6969-6977.
Protocols by Guadalupe Ortiz-Muñoz
  1. Non-invasive Intratracheal Instillation in Mice
  2. Two-event Transfusion-related Acute Lung Injury Mouse Model