Welcome guest, Sign in


Shotaro  Michinaga

Shotaro Michinaga


Ph.D. in Pharmacology, Department of Pharmacology, Kumamoto University, 2013

Current position

Assistant Professor in Laboratory of Pharmacology, Faculty of Pharmacy, Osaka Ohtani University, Japan


  1. Koyama, Y. and Michinaga, S. (2014). Roles of astroglia in the regulations of brain vascular permeability. Nihon Yakurigaku Zasshi 144(3): 115-119.
  2. Michinaga, S., Nagase, M., Matsuyama, E., Yamanaka, D., Seno, N., Fuka, M., Yamamoto, Y. and Koyama, Y. (2014). Amelioration of cold injury-induced cortical brain edema formation by selective endothelin ETB receptor antagonists in mice. PLoS One 9(7): e102009.
  3. Koyama, Y., Kotani, M., Sawamura, T., Kuribayashi, M., Konishi, R. and Michinaga, S. (2013). Different actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1. J Neuroinflammation 10: 51.
  4. Michinaga, S., Ishida, A., Takeuchi, R. and Koyama, Y. (2013). Endothelin-1 stimulates cyclin D1 expression in rat cultured astrocytes via activation of Sp1. Neurochem Int 63(1): 25-34.
  5. Koyama, Y., Maebara, Y., Hayashi, M., Nagae, R., Tokuyama, S. and Michinaga, S. (2012). Endothelins reciprocally regulate VEGF-A and angiopoietin-1 production in cultured rat astrocytes: implications on astrocytic proliferation. Glia 60(12): 1954-1963.
  6. Katsuki, H. and Michinaga, S. (2012). Anti-Parkinson drugs and orexin neurons. Vitam Horm 89: 279-290.
  7. Koyama, Y. and Michinaga, S. (2012). Regulations of astrocytic functions by endothelins: roles in the pathophysiological responses of damaged brains. J Pharmacol Sci 118(4): 401-407.
  8. Michinaga, S., Hisatsune, A., Isohama, Y. and Katsuki, H. (2011). Orexin neurons in hypothalamic slice cultures are vulnerable to endoplasmic reticulum stress. Neuroscience 190: 289-300.
  9. Michinaga, S., Hisatsune, A., Isohama, Y. and Katsuki, H. (2010). An anti-Parkinson drug ropinirole depletes orexin from rat hypothalamic slice culture. Neurosci Res 68(4): 315-321.
  10. Katsuki, H., Kurosu, S., Michinaga, S., Hisatsune, A., Isohama, Y., Izumi, Y., Kume, T. and Akaike, A. (2010). Depolarizing stimuli cause persistent and selective loss of orexin in rat hypothalamic slice culture. Peptides 31(6): 1131-1138.
  11. Michinaga, S., Hisatsune, A., Isohama, Y. and Katsuki, H. (2010). Inhibition of neural activity depletes orexin from rat hypothalamic slice culture. J Neurosci Res 88(1): 214-221.
Protocols by Shotaro Michinaga
  1. ELISA Detection of Endogenous Serum Albumin in the Mouse Brain: A Measure of Extravasation Following Brain Injury