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Antoine de Morrée


Ph.D. in Human Genetics, Leiden University Medical Center, the Netherlands, 2011

Current position

Aging is the number 1 risk factor for disease, but is little understood. As a postdoctoral scholar at Stanford and VA Palo Alto I investigate how age limits the ability of adult stem cells to heal tissue injuries, with the hope of finding interventions that make you live healthier longer.


  1. de Morrée, A. (2014). Outside the tower. A night at the museum. Science 345(6194): 279.
  2. de Morrée, A., Flix, B., Bagaric, I., Wang, J., van den Boogaard, M., Grand Moursel, L., Frants, R. R., Illa, I., Gallardo, E., Toes, R. and van der Maarel, S. M. (2013). Dysferlin regulates cell adhesion in human monocytes. J Biol Chem 288(20): 14147-14157.
  3. Maiuri, P., Terriac, E., Paul-Gilloteaux, P., Vignaud, T., McNally, K., Onuffer, J., Thorn, K., Nguyen, P. A., Georgoulia, N., Soong, D., Jayo, A., Beil, N., Beneke, J., Lim, J. C., Sim, C. P., Chu, Y. S., participants, W. C. R., Jimenez-Dalmaroni, A., Joanny, J. F., Thiery, J. P., Erfle, H., Parsons, M., Mitchison, T. J., Lim, W. A., Lennon-Dumenil, A. M., Piel, M. and Thery, M. (2012). The first World Cell Race. Curr Biol 22(17): R673-675.
  4. de Morrée, A. (2012). Unifying disease mechanisms; looking at similarities and differences. J Cell Sci Ther 3: e109.
  5. Gallardo, E., de Luna, N., Diaz-Manera, J., Rojas-Garcia, R., Gonzalez-Quereda, L., Flix, B., de Morrée, A., van der Maarel, S. and Illa, I. (2011). Comparison of dysferlin expression in human skeletal muscle with that in monocytes for the diagnosis of dysferlin myopathy. PLoS One 6(12): e29061.
  6. Humphrey, G. W., Mekhedov, E., Blank, P. S., de Morrée, A., Pekkurnaz, G., Nagaraju, K. and Zimmerberg, J. (2012). GREG cells, a dysferlin-deficient myogenic mouse cell line. Exp Cell Res 318(2): 127-135.
  7. de Morrée, A., Droog, M., Grand Moursel, L., Bisschop, I. J. M., Impagliazzo, A., Frants, R. R., Klooster, R. and van der Maarel, S. M. (2012). Self-regulated alternative splicing at the AHNAK locus. FASEB J 26(1): 93-103.
  8. van Haagen, H. H., t Hoen, P. A., de Morrée, A., van Roon-Mom, W. M., Peters, D. J., Roos, M., Mons, B., van Ommen, G. J. and Schuemie, M. J. (2011). In silico discovery and experimental validation of new protein-protein interactions. Proteomics 11(5): 843-853.
  9. de Morrée, A., Hensbergen, P. J., van Haagen, H. H., Dragan, I., Deelder, A. M., t Hoen, P. A., Frants, R. R. and van der Maarel, S. M. (2010). Proteomic analysis of the dysferlin protein complex unveils its importance for sarcolemmal maintenance and integrity. PLoS One 5(11): e13854.
  10. de Morrée, A., Lutje Hulsik, D., Impagliazzo, A., van Haagen, H. H., de Galan, P., van Remoortere, A., t Hoen, P. A., van Ommen, G. B., Frants, R. R. and van der Maarel, S. M. (2010). Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodeling. PLoS One 5(8): e11940.
  11. van Haagen, H. H., t Hoen, P. A., Botelho Bovo, A., de Morrée, A., van Mulligen, E. M., Chichester, C., Kors, J. A., den Dunnen, J. T., van Ommen, G. J., van der Maarel, S. M., Kern, V. M., Mons, B. and Schuemie, M. J. (2009). Novel protein-protein interactions inferred from literature context. PLoS One 4(11): e7894.
  12. Huang, Y.*, de Morrée, A.*, van Remoortere, A., Bushby, K., Frants, R. R., den Dunnen, J. T. and van der Maarel, S. M. (2008). Calpain 3 is a modulator of the dysferlin protein complex in skeletal muscle. Hum Mol Genet 17(12): 1855-1866. (*Shared first authorship)
  13. Smolenaars, M. M., de Morrée, A., Kerver, J., Van der Horst, D. J. and Rodenburg, K. W. (2007). Insect lipoprotein biogenesis depends on an amphipathic beta cluster in apolipophorin II/I and is stimulated by microsomal triglyceride transfer protein. J Lipid Res 48(9): 1955-1965.