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Vance G. Fowler Jr

Education

Intern/Resident, Duke University Medical Center, Durham, NC, 1996
M.D., University of North Carolina, Chapel Hill, NC, 1993

Current position

Professor with Tenure, Departments of Medicine and Molecular Genetics & Microbiology

Publications

Selected from >180 peer-reviewed publications

  1. Holland, T. L., Arnold, C. and Fowler, V. G., Jr. (2014). Clinical management of Staphylococcus aureus bacteremia: a review. JAMA 312(13): 1330-1341.
  2. Thaden, J. T., Lewis, S. S., Hazen, K. C., Huslage, K., Fowler, V. G., Jr., Moehring, R. W., Chen, L. F., Jones, C. D., Moore, Z. S., Sexton, D. J. and Anderson, D. J. (2014). Rising rates of carbapenem-resistant enterobacteriaceae in community hospitals: a mixed-methods review of epidemiology and microbiology practices in a network of community hospitals in the southeastern United States. Infect Control Hosp Epidemiol 35(8): 978-983.
  3. Yan, Q., Sharma-Kuinkel, B. K., Deshmukh, H., Tsalik, E. L., Cyr, D. D., Lucas, J., Woods, C. W., Scott, W. K., Sempowski, G. D., Thaden, J. T., Rude, T. H., Ahn, S. H. and Fowler, V. G., Jr. (2014). Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis. PLoS Pathog 10(6): e1004149.
  4. Tong, S. Y., Sharma-Kuinkel, B. K., Thaden, J. T., Whitney, A. R., Yang, S. J., Mishra, N. N., Rude, T., Lilliebridge, R. A., Selim, M. A., Ahn, S. H., Holt, D. C., Giffard, P. M., Bayer, A. S., Deleo, F. R. and Fowler, V. G., Jr. (2013). Virulence of endemic nonpigmented northern Australian Staphylococcus aureus clone (clonal complex 75, S. argenteus) is not augmented by staphyloxanthin. J Infect Dis 208(3): 520-527.
  5. Ahn, S. H.*, Tsalik, E. L.*, Cyr, D. D., Zhang, Y., van Velkinburgh, J. C., Langley, R. J., Glickman, S. W., Cairns, C. B., Zaas, A. K., Rivers, E. P., Otero, R. M., Veldman, T., Kingsmore, S. F., Lucas, J., Woods, C. W., Ginsburg, G. S. and Fowler, V. G., Jr. (2013). Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans. PLoS One 8(1): e48979.
  6. Federspiel, J. J., Stearns, S. C., Peppercorn, A. F., Chu, V. H. and Fowler, V. G., Jr. (2012). Endocarditis trends in the United States demonstrate increasing rates of S. aureus: 1999-2008. Archives of Internal Medicine 172: 363-5.
  7. Sharma-Kuinkel, B. K., Ahn, S. H., Rude, T. H., Zhang, Y., Tong, S. Y., Ruffin, F., Genter, F. C., Braughton, K. R., Deleo, F. R., Barriere, S. L. and Fowler, V. G., Jr. (2012). Presence of genes encoding panton-valentine leukocidin is not the primary determinant of outcome in patients with hospital-acquired pneumonia due to Staphylococcus aureus. J Clin Microbiol 50(3): 848-856.
  8. Lower, S. K., Lamlertthon, S., Casillas-Ituarte, N. N., Lins, R. D., Yongsunthon, R., Taylor, E. S., DiBartola, A. C., Edmonson, C., McIntyre, L. M., Reller, L. B., Que, Y. A., Ros, R., Lower, B. H. and Fowler, V. G., Jr. (2011). Polymorphisms in fibronectin binding protein A of Staphylococcus aureus are associated with infection of cardiovascular devices. Proc Natl Acad Sci U S A 108(45): 18372-18377.
  9. Nienaber, J. J., Sharma Kuinkel, B. K., Clarke-Pearson, M., Lamlertthon, S., Park, L., Rude, T. H., Barriere, S., Woods, C. W., Chu, V. H., Marin, M., Bukovski, S., Garcia, P., Corey, G. R., Korman, T., Doco-Lecompte, T., Murdoch, D. R., Reller, L. B., Fowler, V. G., Jr. and International Collaboration on Endocarditis-Microbiology, I. (2011). Methicillin-susceptible Staphylococcus aureus endocarditis isolates are associated with clonal complex 30 genotype and a distinct repertoire of enterotoxins and adhesins. J Infect Dis 204(5): 704-713.
  10. Ahn, S. H., Deshmukh, H., Johnson, N., Cowell, L. G., Rude, T. H., Scott, W. K., Nelson, C. L., Zaas, A. K., Marchuk, D. A., Keum, S., Lamlertthon, S., Sharma-Kuinkel, B. K., Sempowski, G. D. and Fowler, V. G., Jr. (2010). Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. PLoS Pathog 6(9): e1001088.
  11. Buck, A. W., Fowler Jr, V. G., Yongsunthon, R., Liu, J., DiBartola, A. C., Que, Y. A., Moreillon, P. and Lower, S. K. (2010). Bonds between fibronectin and fibronectin-binding proteins on Staphylococcus aureus and Lactococcus lactis. Langmuir 26(13): 10764-10770.
  12. Anderson, D. J., Arduino, J. M., Reed, S. D., Sexton, D. J., Kaye, K. S., Grussemeyer, C. A., Peter, S. A., Hardy, C., Choi, Y. I., Friedman, J. Y. and Fowler, V. G., Jr. (2010). Variation in the type and frequency of postoperative invasive Staphylococcus aureus infections according to type of surgical procedure. Infect Control Hosp Epidemiol 31(7): 701-709.
  13. Chu, V. H., Miro, J. M., Hoen, B., Cabell, C. H., Pappas, P. A., Jones, P., Stryjewski, M. E., Anguera, I., Braun, S., Munoz, P., Commerford, P., Tornos, P., Francis, J., Oyonarte, M., Selton-Suty, C., Morris, A. J., Habib, G., Almirante, B., Sexton, D. J., Corey, G. R., Fowler, V. G., Jr. and International Collaboration on Endocarditis-Prospective Cohort Study, G. (2009). Coagulase-negative staphylococcal prosthetic valve endocarditis--a contemporary update based on the International Collaboration on Endocarditis: prospective cohort study. Heart 95(7): 570-576.
  14. Deshmukh, H. S., Hamburger, J. B., Ahn, S. H., McCafferty, D. G., Yang, S. R. and Fowler, V. G., Jr. (2009). Critical role of NOD2 in regulating the immune response to Staphylococcus aureus. Infect Immun 77(4): 1376-1382.
  15. Bae, I. G., Federspiel, J. J., Miro, J. M., Woods, C. W., Park, L., Rybak, M. J., Rude, T. H., Bradley, S., Bukovski, S., de la Maria, C. G., Kanj, S. S., Korman, T. M., Marco, F., Murdoch, D. R., Plesiat, P., Rodriguez-Creixems, M., Reinbott, P., Steed, L., Tattevin, P., Tripodi, M. F., Newton, K. L., Corey, G. R., Fowler, V. G., Jr. and International Collaboration on Endocarditis-Microbiology, I. (2009). Heterogeneous vancomycin-intermediate susceptibility phenotype in bloodstream methicillin-resistant Staphylococcus aureus isolates from an international cohort of patients with infective endocarditis: prevalence, genotype, and clinical significance. J Infect Dis 200(9): 1355-1366.
Protocols by Vance G. Fowler
  1. Macrophage Phagocytosis Assay of Staphylococcus aureus by Flow Cytometry