Welcome guest, Login | Register


Young-Hee Jin


Ph.D. in Immunology, Ajou University School of Medicine, Suwon, Korea, 2014

Current position

Research Associate Professor, Laboratory of Immune Regulation, Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea (09/2013-present)


  1. Hou, W., Jin, Y. H., Kang, H. S. and Kim, B. S. (2014). Interleukin-6 (IL-6) and IL-17 synergistically promote viral persistence by inhibiting cellular apoptosis and cytotoxic T cell function. J Virol 88(15): 8479-8489.
  2. Jin, Y. H.*, Kang, H. S.*, Hou, W.*, Meng, L., and Kim B. S. (2014). The level of viral infection of antigen-presenting cells is critical for the development of TMEV-induced demyelinating disease. J Virol 02471-02514. (*Contributed equally)
  3. Jin, Y. H., Hou, W., Kang, H. S., Koh, C. S. and Kim, B. S. (2013). The role of interleukin-6 in the expression of PD-1 and PDL-1 on central nervous system cells following infection with Theiler's murine encephalomyelitis virus. J Virol 87(21): 11538-11551.
  4. Jin, Y. H.*, Kim, S. J.*, So, E. Y., Meng, L., Colonna, M. and Kim, B. S. (2012). Melanoma differentiation-associated gene 5 is critical for protection against Theiler's virus-induced demyelinating disease. J Virol 86(3): 1531-1543. (*Contributed equally)
  5. Kim, B. S., Jin, Y. H., Meng, L., Hou, W., Kang, H. S., Park, H. S. and Koh, C. S. (2012). IL-1 signal affects both protection and pathogenesis of virus-induced chronic CNS demyelinating disease. J Neuroinflammation 9(1): 217.
  6. Richards, M. H., Getts, M. T., Podojil, J. R., Jin, Y. H., Kim, B. S. and Miller, S. D. (2011). Virus expanded regulatory T cells control disease severity in the Theiler's virus mouse model of MS. J Autoimmun 36(2): 142-154.
  7. Jin, Y. H., Kaneyama, T., Kang, M. H., Kang, H. S., Koh, C. S. and Kim, B. S. (2011). TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection. J Neuroinflammation 8: 178.
  8. Jin, Y. H., Kang, H. S., Mohindru, M. and Kim, B. S. (2011). Preferential induction of protective T cell responses to Theiler's virus in resistant (C57BL/6 x SJL)F1 mice. J Virol 85(6): 3033-3040.
  9. Takeichi, N., Yanagisawa, S., Kaneyama, T., Yagita, H., Jin, Y. H., Kim, B. S. and Koh, C. S. (2010). Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease. Int Immunol 22(9): 729-738.
  10. Jin, Y. H., Hou, W., Kim, S. J., Fuller, A. C., Kang, B., Goings, G., Miller, S. D. and Kim, B. S. (2010). Type I interferon signals control Theiler's virus infection site, cellular infiltration and T cell stimulation in the CNS. J Neuroimmunol 226(1-2): 27-37.
  11. Lee, M. J., Jin, Y. H., Kim, K., Choi, Y., Kim, H. C. and Park, S. (2010). Expression of hepatitis B virus x protein in hepatocytes suppresses CD8 T cell activity. Immune Netw 10(4): 126-134.
  12. Jin, Y. H.*, Kang, B.*, and Kim, B. S. (2009). Theiler's virus infection induces a predominant pathogenic CD4+ T cell response to RNA polymerase in susceptible SJL/J mice. J Virol 83(21): 10981-10992. (*Contributed equally)
  13. Jin, Y. H., Mohindru, M., Kang, M. H., Fuller, A. C., Kang, B., Gallo, D. and Kim, B. S. (2007). Differential virus replication, cytokine production, and antigen-presenting function by microglia from susceptible and resistant mice infected with Theiler's virus. J Virol 81(21): 11690-11702.
  14. Jin, Y. H., Hong, S. H., Kim, K., Shin, H. J. and Park, S. (2006). Intracellular antibody fragment against hepatitis B virus X protein does not inhibit viral replication. Yonsei Med J 47(5): 721-728.
  15. Jin, Y. H., Kwon, M. H., Kim, K., Shin, H. J., Shin, J. S., Cho, H. and Park, S. (2006). An intracellular antibody can suppress tumorigenicity in hepatitis B virus X-expressing cells. Cancer Immunol Immunother 55(5): 569-578.
  16. Jin, Y. H., Crispe, I. N. and Park, S. (2005). Expression of hepatitis C virus core protein in hepatocytes does not modulate proliferation or apoptosis of CD8+ T cells. Yonsei Med J 46(6): 827-834.
  17. Jin, Y. H., Kim, H. I., and Park, S. (2003) Expression of intracellular single chain antibody specific to hepatitis B virus X protein. Immune Network 3(1):23-28. 
  18. Yun, C., Um, H. R., Jin, Y. H., Wang, J. H., Lee, M. O., Park, S., Lee, J. H. and Cho, H. (2002). NF-kappaB activation by hepatitis B virus X (HBx) protein shifts the cellular fate toward survival. Cancer Lett 184(1): 97-104.
  19. Park, O. Y., Jin, Y. H., Lee, M., Shin, H. J., Kim, H. I., Cho, H., Yun, C. W., Youn, J. K. and Park, S. (2000). Characterization and gene cloning of monoclonal antibody specific for the hepatitis B virus X protein. Hybridoma 19(1): 73-80.
  20. Jin, Y. H., Park, O. Y., Kang K., Kang H. S., and Kim H. I. (1998). Heat shock response inhibits IFN- plus LPS-induced NO synthase expression in murine peritoneal macrophage. Korean J Immunol 20(3): 263-268.

Protocols by Young-Hee Jin
  1. Isolation of CNS-infiltrating and Resident Microglial Cells